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突然扩张流槽中血管内皮细胞表面粘附蛋白表达的研究
Alternative TitleExpression of surface adhesion proteins on cultured vascular endothelial cells in sudden-expension flow chamber
胡江; 胡嘉; 李涛; 高宇欣; 陶祖莱
Source Publication生物物理学报
2003-03-30
Volume19Issue:1Pages:97-100
Abstract动脉粥样硬化的非随机分布与当地的血流动力环境有关,为了研究复杂的流体动力学条件对血和皮细胞生理功能的影响,构建了平行板式平直流槽和突然扩张流槽,通过数值模拟分析了流型的特征,并探讨流型改变对人脐静脉血管内皮细胞表面粘附蛋白表达的影响,发现突然扩张流槽中流动的空间变化使得总体细胞表面粘附蛋白ICAM-1的表达显著高于平直流槽中的均匀定常剪切作用,表明局部流动空间变化的性质可以影响血管内皮细胞的功能。
Keyword流型 内皮细胞 表面粘附蛋白
Indexed ByCSCD
Language中文
Funding Organization国家自然科学基金项目(19732003)
CSCD IDCSCD:1349257
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Document Type期刊论文
Identifierhttp://dspace.imech.ac.cn/handle/311007/42364
Collection力学所知识产出(1956-2008)
Corresponding Author胡江
Recommended Citation
GB/T 7714
胡江,胡嘉,李涛,等. 突然扩张流槽中血管内皮细胞表面粘附蛋白表达的研究[J]. 生物物理学报,2003,19(1):97-100.
APA 胡江,胡嘉,李涛,高宇欣,&陶祖莱.(2003).突然扩张流槽中血管内皮细胞表面粘附蛋白表达的研究.生物物理学报,19(1),97-100.
MLA 胡江,et al."突然扩张流槽中血管内皮细胞表面粘附蛋白表达的研究".生物物理学报 19.1(2003):97-100.
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