|Surface Initiated Polymerization from Substrates of Low Initiator Density and Its Applications in Biosensors|
|Ma HW; He JA; Liu X; Gan JH; Jin G(靳刚); Zhou JH; Jin G
|Source Publication||Acs Applied Materials & Interfaces
|Abstract||Surface initiated polymerization (SIP) has become an attractive method for tailoring physical and chemical properties of surfaces for a broad range of applications. Most of those application relied on the merit of a high density coating. In this study we explored a long overlooked field of SIP. SIP from substrates of low initiator density. We combined ellipsometry with AFM to investigate the effect of initiatior density and polymerization time on the morphology of polymer coatings. In addition, we carefully adjusted the nanoscale separation of polymer chains to achieve a balance between nonfouling and immobilization capacities. We further tested the performance of those coating on various biosensors, such as quartz crystal microbalance, surface plasmon resonance, and protein microarrays. The optimized matrices enhanced the performance of those biosensors. This report shall encourage researches to explore new frontiers in SIP that go beyond polymer brushes.|
|Keyword||Surface Initiated Polymerization
Quartz Crystal Microbalance
Surface Plasmon Resonance
Transfer Radical Polymerization
|WOS Keyword||TRANSFER RADICAL POLYMERIZATION
; POLY(ETHYLENE GLYCOL)
; RESPONSIVE POLYMERS
; AQUEOUS ATRP
|WOS Research Area||Science & Technology - Other Topics
; Materials Science
|WOS Subject||Nanoscience & Nanotechnology
; Materials Science, Multidisciplinary
|Funding Organization||Chinese Academy of Sciences [08BM031001]
; Special Foundation of the President of the Chinese Academy of Sciences, NSFC 
; National High Technology Research and Development Program of China [2009AA04Z125]
; National Basic Research Program of China [2009CB320300]
|Corresponding Author||Jin G|
Ma HW,He JA,Liu X,et al. Surface Initiated Polymerization from Substrates of Low Initiator Density and Its Applications in Biosensors[J]. Acs Applied Materials & Interfaces,2010,2(11):3223-3230.
Ma HW.,He JA.,Liu X.,Gan JH.,靳刚.,...&Jin G.(2010).Surface Initiated Polymerization from Substrates of Low Initiator Density and Its Applications in Biosensors.Acs Applied Materials & Interfaces,2(11),3223-3230.
Ma HW,et al."Surface Initiated Polymerization from Substrates of Low Initiator Density and Its Applications in Biosensors".Acs Applied Materials & Interfaces 2.11(2010):3223-3230.