Surface Initiated Polymerization from Substrates of Low Initiator Density and Its Applications in Biosensors

doi:10.1021/am1006832

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	Surface Initiated Polymerization from Substrates of Low Initiator Density and Its Applications in Biosensors
	Ma HW; He JA; Liu X; Gan JH; Jin G(靳刚); Zhou JH; Jin G
发表期刊	Acs Applied Materials & Interfaces
	2010
卷号	2 期号:11 页码:3223-3230
ISSN	1944-8244
摘要	Surface initiated polymerization (SIP) has become an attractive method for tailoring physical and chemical properties of surfaces for a broad range of applications. Most of those application relied on the merit of a high density coating. In this study we explored a long overlooked field of SIP. SIP from substrates of low initiator density. We combined ellipsometry with AFM to investigate the effect of initiatior density and polymerization time on the morphology of polymer coatings. In addition, we carefully adjusted the nanoscale separation of polymer chains to achieve a balance between nonfouling and immobilization capacities. We further tested the performance of those coating on various biosensors, such as quartz crystal microbalance, surface plasmon resonance, and protein microarrays. The optimized matrices enhanced the performance of those biosensors. This report shall encourage researches to explore new frontiers in SIP that go beyond polymer brushes.
关键词	Surface Initiated Polymerization Biosensor Matrix Quartz Crystal Microbalance Surface Plasmon Resonance Protein Microarray Transfer Radical Polymerization Poly(Ethylene Glycol) Responsive Polymers Aqueous Atrp Brushes Protein Gold Poly(Dimethylsiloxane) Functionalization Adsorption
DOI	10.1021/am1006832
URL	查看原文
收录类别	SCI
语种	英语
WOS记录号	WOS:000284454400037
关键词[WOS]	TRANSFER RADICAL POLYMERIZATION ; POLY(ETHYLENE GLYCOL) ; RESPONSIVE POLYMERS ; AQUEOUS ATRP ; BRUSHES ; PROTEIN ; GOLD ; POLY(DIMETHYLSILOXANE) ; FUNCTIONALIZATION ; ADSORPTION
WOS研究方向	Science & Technology - Other Topics ; Materials Science
WOS类目	Nanoscience & Nanotechnology ; Materials Science, Multidisciplinary
项目资助者	Chinese Academy of Sciences [08BM031001] ; Special Foundation of the President of the Chinese Academy of Sciences, NSFC [20604002] ; National High Technology Research and Development Program of China [2009AA04Z125] ; National Basic Research Program of China [2009CB320300]
引用统计	被引频次：51[WOS] [WOS记录] [WOS相关记录]
文献类型	期刊论文
条目标识符	http://dspace.imech.ac.cn/handle/311007/43619
专题	微重力重点实验室
通讯作者	Jin G
推荐引用方式 GB/T 7714	Ma HW,He JA,Liu X,et al. Surface Initiated Polymerization from Substrates of Low Initiator Density and Its Applications in Biosensors[J]. Acs Applied Materials & Interfaces,2010,2,11,:3223-3230.
APA	Ma HW.,He JA.,Liu X.,Gan JH.,靳刚.,...&Jin G.(2010).Surface Initiated Polymerization from Substrates of Low Initiator Density and Its Applications in Biosensors.Acs Applied Materials & Interfaces,2(11),3223-3230.
MLA	Ma HW,et al."Surface Initiated Polymerization from Substrates of Low Initiator Density and Its Applications in Biosensors".Acs Applied Materials & Interfaces 2.11(2010):3223-3230.

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