Development of biosensor based on imaging ellipsometry and biomedical applications

doi:10.1016/j.tsf.2010.12.175

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	Development of biosensor based on imaging ellipsometry and biomedical applications
	Jin G(靳刚); Meng YH(孟永宏); Liu L(刘丽); Niu Y(牛宇); Chen S(陈涉); Cai Q; Jiang TJ; Jin, G (reprint author), Chinese Acad Sci, NML, Inst Mech, 15 Bei Si Huan W Rd, Beijing 100190, Peoples R China
发表期刊	Thin Solid Films
	2011
卷号	519 期号:9 页码:2750-2757
ISSN	0040-6090
摘要	So far, combined with a microfluidic reactor array system, an engineering system of biosensor based on imaging ellipsometry is installed for biomedical applications, such as antibody screen, hepatitis B markers detection, cancer markers spectrum and virus recognition, etc. Furthermore, the biosensor in total internal reflection (TIR) mode has be improved by a spectroscopic light, optimization settings of polarization and low noise CCD which brings an obvious improvement of 10 time increase in the sensitivity and SNR, and 50 times lower concentration in the detection limit with a throughput of 48 independent channels and the time resolution of 0.04 S. (C) 2010 Elsevier B.V. All rights reserved.
关键词	Imaging Ellipsometry Biosensor Protein Microarray Total Internal Reflection Off-null Ellipsometry Optical Protein-chip Optimization Visualization
学科领域	Materials Science ; Physics
DOI	10.1016/j.tsf.2010.12.175
URL	查看原文
收录类别	SCI ; EI
语种	英语
WOS记录号	WOS:000289174200040
关键词[WOS]	OFF-NULL ELLIPSOMETRY ; OPTICAL PROTEIN-CHIP ; OPTIMIZATION ; VISUALIZATION
WOS研究方向	Materials Science ; Physics
WOS类目	Materials Science, Multidisciplinary ; Materials Science, Coatings & Films ; Physics, Applied ; Physics, Condensed Matter
课题组名称	NML纳米生物光学
论文分区	二类/Q2
引用统计	被引频次：33[WOS] [WOS记录] [WOS相关记录]
文献类型	期刊论文
条目标识符	http://dspace.imech.ac.cn/handle/311007/45099
专题	微重力重点实验室
通讯作者	Jin, G (reprint author), Chinese Acad Sci, NML, Inst Mech, 15 Bei Si Huan W Rd, Beijing 100190, Peoples R China
推荐引用方式 GB/T 7714	Jin G,Meng YH,Liu L,et al. Development of biosensor based on imaging ellipsometry and biomedical applications[J]. Thin Solid Films,2011,519,9,:2750-2757.
APA	Jin G.,Meng YH.,Liu L.,Niu Y.,Chen S.,...&Jin, G .(2011).Development of biosensor based on imaging ellipsometry and biomedical applications.Thin Solid Films,519(9),2750-2757.
MLA	Jin G,et al."Development of biosensor based on imaging ellipsometry and biomedical applications".Thin Solid Films 519.9(2011):2750-2757.

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