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Development of biosensor based on imaging ellipsometry and biomedical applications
Jin G(靳刚); Meng YH(孟永宏); Liu L(刘丽); Niu Y(牛宇); Chen S(陈涉); Cai Q; Jiang TJ; Jin, G (reprint author), Chinese Acad Sci, NML, Inst Mech, 15 Bei Si Huan W Rd, Beijing 100190, Peoples R China
会议录名称THIN SOLID FILMS
2011
页码2750-2757
会议名称5th International Conference on Spectroscopic Ellipsometry
会议日期MAY 23-29, 2010
会议地点Albany, NY
摘要So far, combined with a microfluidic reactor array system, an engineering system of biosensor based on imaging ellipsometry is installed for biomedical applications, such as antibody screen, hepatitis B markers detection, cancer markers spectrum and virus recognition, etc. Furthermore, the biosensor in total internal reflection (TIR) mode has be improved by a spectroscopic light, optimization settings of polarization and low noise CCD which brings an obvious improvement of 10 time increase in the sensitivity and SNR, and 50 times lower concentration in the detection limit with a throughput of 48 independent channels and the time resolution of 0.04 S. (C) 2010 Elsevier B.V. All rights reserved.
关键词Imaging Ellipsometry Biosensor Protein Microarray Total Internal Reflection Off-null Ellipsometry Optical Protein-chip Optimization Visualization
课题组名称中科院国家微重力实验室
资助信息Univ Albany, Coll Nanoscale & Engn
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语种英语
文献类型会议论文
条目标识符http://dspace.imech.ac.cn/handle/311007/45317
专题微重力重点实验室
通讯作者Jin, G (reprint author), Chinese Acad Sci, NML, Inst Mech, 15 Bei Si Huan W Rd, Beijing 100190, Peoples R China
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GB/T 7714
Jin G,Meng YH,Liu L,et al. Development of biosensor based on imaging ellipsometry and biomedical applications[C]THIN SOLID FILMS,2011:2750-2757.
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