Development of biosensor based on imaging ellipsometry and biomedical applications | |
Jin G(靳刚); Meng YH(孟永宏); Liu L(刘丽); Niu Y(牛宇); Chen S(陈涉); Cai Q; Jiang TJ; Jin, G (reprint author), Chinese Acad Sci, NML, Inst Mech, 15 Bei Si Huan W Rd, Beijing 100190, Peoples R China | |
会议录名称 | THIN SOLID FILMS |
2011 | |
页码 | 2750-2757 |
会议名称 | 5th International Conference on Spectroscopic Ellipsometry |
会议日期 | MAY 23-29, 2010 |
会议地点 | Albany, NY |
摘要 | So far, combined with a microfluidic reactor array system, an engineering system of biosensor based on imaging ellipsometry is installed for biomedical applications, such as antibody screen, hepatitis B markers detection, cancer markers spectrum and virus recognition, etc. Furthermore, the biosensor in total internal reflection (TIR) mode has be improved by a spectroscopic light, optimization settings of polarization and low noise CCD which brings an obvious improvement of 10 time increase in the sensitivity and SNR, and 50 times lower concentration in the detection limit with a throughput of 48 independent channels and the time resolution of 0.04 S. (C) 2010 Elsevier B.V. All rights reserved. |
关键词 | Imaging Ellipsometry Biosensor Protein Microarray Total Internal Reflection Off-null Ellipsometry Optical Protein-chip Optimization Visualization |
课题组名称 | 中科院国家微重力实验室 |
资助信息 | Univ Albany, Coll Nanoscale & Engn |
URL | 查看原文 |
语种 | 英语 |
文献类型 | 会议论文 |
条目标识符 | http://dspace.imech.ac.cn/handle/311007/45317 |
专题 | 微重力重点实验室 |
通讯作者 | Jin, G (reprint author), Chinese Acad Sci, NML, Inst Mech, 15 Bei Si Huan W Rd, Beijing 100190, Peoples R China |
推荐引用方式 GB/T 7714 | Jin G,Meng YH,Liu L,et al. Development of biosensor based on imaging ellipsometry and biomedical applications[C]THIN SOLID FILMS,2011:2750-2757. |
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