IMECH-IR  > 力学所知识产出(1956-2008)
共价固定生物分子的蛋白质芯片及其制备方法
靳刚; 王战会
2005-09-21
Rights Holder中国科学院力学研究所
Abstract本发明涉及一种在固体表面上共价固定配基分子的蛋白质芯片。该芯片采用氯硅烷聚乙二醇衍生物作为改性层和固体基片共价连接,配基感应膜层通过共价键和氯硅烷聚乙二醇衍生物的活性基团连接。用这种方法制备的芯片能有效提高配基分子的稳定性,抑制固体表面对非目标蛋白质的吸附从而减少假阳性结果的发生。该芯片可以广泛用于各类生物分子如抗体、抗原、受体、配体、DNA片段等的检测。
Application Date2002-05-29
Date Available2012-12-28
Patent NumberZL02120716.X
Language中文
Country中国
Document Type专利
Identifierhttp://dspace.imech.ac.cn/handle/311007/45925
Collection力学所知识产出(1956-2008)
Recommended Citation
GB/T 7714
靳刚,王战会. 共价固定生物分子的蛋白质芯片及其制备方法. ZL02120716.X[P]. 2005-09-21.
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