共价固定生物分子的蛋白质芯片及其制备方法

IMECH-IR > 力学所知识产出(1956-2008)

	共价固定生物分子的蛋白质芯片及其制备方法
	靳刚; 王战会
	2005-09-21
Rights Holder	中国科学院力学研究所
Abstract	本发明涉及一种在固体表面上共价固定配基分子的蛋白质芯片。该芯片采用氯硅烷聚乙二醇衍生物作为改性层和固体基片共价连接，配基感应膜层通过共价键和氯硅烷聚乙二醇衍生物的活性基团连接。用这种方法制备的芯片能有效提高配基分子的稳定性，抑制固体表面对非目标蛋白质的吸附从而减少假阳性结果的发生。该芯片可以广泛用于各类生物分子如抗体、抗原、受体、配体、DNA片段等的检测。
Application Date	2002-05-29
Date Available	2012-12-28
Patent Number	ZL02120716.X
Language	中文
Country	中国
Document Type	专利
Identifier	http://dspace.imech.ac.cn/handle/311007/45925
Collection	力学所知识产出(1956-2008)
Recommended Citation GB/T 7714	靳刚,王战会. 共价固定生物分子的蛋白质芯片及其制备方法. ZL02120716.X[P]. 2005-09-21.

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