Cellular entry of graphene nanosheets: The role of thickness, oxidation and surface adsorption

IMECH-IR > 非线性力学国家重点实验室

	Cellular entry of graphene nanosheets: The role of thickness, oxidation and surface adsorption
	Wang JL(王九令); Wei YJ(魏宇杰); Shi XH(施兴华); Gao HJ; Shi, XH (reprint author), Chinese Acad Sci, Inst Mech, State Key Lab Nonlinear Mech, Beijing 100190, Peoples R China.
发表期刊	RSC ADVANCES
	2013-09-28
卷号	3 期号:36 页码:15776-15782
ISSN	2046-2069
摘要	Coarse grained molecular dynamics simulations are conducted to study the interaction of graphene nanosheets with a lipid bilayer, focusing on the effects of graphene thicknesses (single/multi-layered graphene), oxidation and surface absorption by lipid molecules. The results show that a hydrophobic corner of graphene can pierce into the bilayer, while different oxidations of the nanosheets affect their final equilibrium configurations in the bilayer: lying across or within the hydrophobic core of the bilayer. The underlying mechanism is clarified by calculating the energy barrier for graphene piercing into the bilayer. Our studies provide fundamental guidance towards understanding how graphene enters cells, which is important for biomedical diagnostics and therapies, and for managing health impacts following occupational or environmental exposure.
关键词	Carbon Nanotubes Graphene Nanosheets Lipid-bilayers Coarse-grained Model Molecular-dynamics Hydrophobicity Surface Absorption Oxidation Bio Medical Diagnosticscarbon Nanotubes Graphene Nanosheets Lipid-bilayers Coarse-grained Model Molecular-dynamics Hydrophobicity Surface Absorption Oxidation Bio Medical Diagnostics
学科领域	固体力学
URL	查看原文
收录类别	SCI ; EI
语种	英语
WOS记录号	WOS:000323271700037
项目资助者	National Natural Science Foundation of China (NSFC) [11272327]; National Science Foundation (NSF) [CMMI-1028530]; Supercomputing Center of Chinese Academy of Sciences (SCCAS)
课题组名称	LNM微结构计算力学（筹）
论文分区	二类/Q2
引用统计	被引频次：113[WOS] [WOS记录] [WOS相关记录]
文献类型	期刊论文
条目标识符	http://dspace.imech.ac.cn/handle/311007/47462
专题	非线性力学国家重点实验室
通讯作者	Shi, XH (reprint author), Chinese Acad Sci, Inst Mech, State Key Lab Nonlinear Mech, Beijing 100190, Peoples R China.
推荐引用方式 GB/T 7714	Wang JL,Wei YJ,Shi XH,et al. Cellular entry of graphene nanosheets: The role of thickness, oxidation and surface adsorption[J]. RSC ADVANCES,2013,3,36,:15776-15782.
APA	Wang JL,Wei YJ,Shi XH,Gao HJ,&Shi, XH .(2013).Cellular entry of graphene nanosheets: The role of thickness, oxidation and surface adsorption.RSC ADVANCES,3(36),15776-15782.
MLA	Wang JL,et al."Cellular entry of graphene nanosheets: The role of thickness, oxidation and surface adsorption".RSC ADVANCES 3.36(2013):15776-15782.

条目包含的文件		下载所有文件
文件名称/大小	文献类型	版本类型	开放类型	使用许可
IMCAS-J2013-252.pdf（1262KB）			开放获取	--	浏览下载