IMECH-IR  > 非线性力学国家重点实验室
A tough graphene nanosheet/hydroxyapatite composite with improved in vitro biocompatibility
Zhang L; Liu WW; Yue CG; Zhang TH(张泰华); Li P; Xing ZW; Chen Y; Chen, Y (reprint author), Soochow Univ, Sch Mech & Elect Engn, Biomfg Res Ctr, 178 East Ganjiang Rd, Suzhou 215021, Peoples R China.
Source PublicationCARBON
2013-09
Volume61Pages:105-115
ISSN0008-6223
AbstractMechanical properties and in vitro biocompatibility of graphene/hydroxyapatite (HA) composite synthesized using spark plasma sintering (SPS) are reported in this study. Raman spectroscopy corroborated that graphene nanosheets (GNSs) survived the harsh processing conditions of the selected SPS processing parameters. A 1.0 wt.% GNS/HA composite exhibits similar to 80% improvement in fracture toughness as compared to pure HA. GNS pull-out, grain bridging by GNS, crack bridging and crack deflection are the major toughening mechanisms that resist crack propagation. In vitro osteoblast growth tests illustrate that the added GNSs contribute to the improvement of both osteoblast adhesion and apatite mineralization. Therefore, the GNS/HA composite is expected to be a promising material for load-bearing orthopedic implants. (C) 2013 Elsevier Ltd. All rights reserved.
KeywordHa Coatings Hydroxyapatite Nanocomposites Mineralization Nanoindentation
Subject Area新型材料的力学问题 ; 实验固体力学
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Indexed BySCI ; EI
Language英语
WOS IDWOS:000322208700011
Funding OrganizationNational Natural Science Foundation of China [51275326, 11025212, 11272318]; Natural Science Foundation of Jiangsu Province of China [SBK2010212]; Opening fund of The State Key Laboratory of Nonlinear Mechanics
DepartmentLNM实验平台
Classification一类
Citation statistics
Cited Times:132[WOS]   [WOS Record]     [Related Records in WOS]
Document Type期刊论文
Identifierhttp://dspace.imech.ac.cn/handle/311007/47477
Collection非线性力学国家重点实验室
Corresponding AuthorChen, Y (reprint author), Soochow Univ, Sch Mech & Elect Engn, Biomfg Res Ctr, 178 East Ganjiang Rd, Suzhou 215021, Peoples R China.
Recommended Citation
GB/T 7714
Zhang L,Liu WW,Yue CG,et al. A tough graphene nanosheet/hydroxyapatite composite with improved in vitro biocompatibility[J]. CARBON,2013,61:105-115
APA Zhang L.,Liu WW.,Yue CG.,张泰华.,Li P.,...&Chen, Y .(2013).A tough graphene nanosheet/hydroxyapatite composite with improved in vitro biocompatibility.CARBON,61,105-115.
MLA Zhang L,et al."A tough graphene nanosheet/hydroxyapatite composite with improved in vitro biocompatibility".CARBON 61(2013):105-115.
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