Hydrodynamic cell enrichment in double spiral microfluidic channels | |
Sun JS; Li MM; Liu C(刘超); Hu GQ(胡国庆); Jiang XY; Sun Jiashu | |
会议录名称 | Chemical Sensors 10 -and- MEMS/NEMS 10 |
2012 | |
页码 | 441-445 |
会议名称 | Symposia on Chemical Sensors 10 - Chemical and Biological Sensors and Analytical Systems and Microfabricated and Nanofabricated Systems for MEMS/NEMS 10 - 222nd ECS Meeting/PRiME 2012 |
会议日期 | OCT 07-12, 2012 |
会议地点 | Honolulu, HI, United states |
摘要 | Rapid cell separation and enrichment has attracted significant attention because of its important applications in cell biology studies and biomedical diagnostics. we have developed a compact microfluidic platform, composed of 6-loop double spiral microchannels, to separate cancer cells from blood cells. The curved geometry induces a Dean drag force acting on cells to compete with the inertial lift, resulting in different equilibrium positions for different sized cells. The separation chip is characterized with the mixture of 4T1 cells and the murine blood cells at different flow rates, with decent separation and enrichment efficiency. |
WOS记录号 | WOS:000338266800056 |
课题组名称 | LNM微纳米流体力学 |
资助信息 | MOST 2011CB933201 2009CB930001 2011CB707604 NSFC 51105086 21025520 90813032 CAS KJCX2-YW-M15 KJCX2YW-H18 |
ISBN号 | 9781607683605 |
URL | 查看原文 |
收录类别 | CPCI-S ; EI |
语种 | 英语 |
引用统计 | |
文献类型 | 会议论文 |
条目标识符 | http://dspace.imech.ac.cn/handle/311007/48288 |
专题 | 非线性力学国家重点实验室 |
通讯作者 | Sun Jiashu |
推荐引用方式 GB/T 7714 | Sun JS,Li MM,Liu C,et al. Hydrodynamic cell enrichment in double spiral microfluidic channels[C]Chemical Sensors 10 -and- MEMS/NEMS 10,2012:441-445. |
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