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Joule heating effects on reservoir-based dielectrophoresis
Kale A; Patel S; Qian SZ; Hu GQ(胡国庆); Xuan XC; Xuan, XC (reprint author), Clemson Univ, Dept Mech Engn, Clemson, SC 29634 USA.
Source PublicationElectrophoresis
AbstractReservoir-based dielectrophoresis (rDEP) is a recently developed technique that exploits the inherent electric field gradients at a reservoir-microchannel junction to focus, trap, and sort particles. However, the locally amplified electric field at the junction is likely to induce significant Joule heating effects that are not considered in previous studies. This work investigates experimentally and numerically these effects on particle transport and control in rDEP processes in PDMS/PDMS microchips. It is found that Joule heating effects can reduce rDEP focusing considerably and may even disable rDEP trapping. This is caused by the fluid temperature rise at the reservoir-microchannel junction, which significantly increases the local particle velocity due to fluid flow and particle electrophoresis while has a weak impact on the particle velocity due to rDEP. The numerical predictions of particle stream width and electric current, which are the respective indicators of rDEP manipulation and fluid temperature, are demonstrated to both match the experimental measurements with a good accuracy.
Subject AreaBiochemistry & Molecular Biology ; Chemistry
Indexed BySCI
WOS IDWOS:000332342200014
Funding OrganizationThis work is partially supported by NSF under grant CBET-0853873 (Xuan), NRF of Korea under grant 2011-0014246 (Qian), and by NSFC under grant 11272321 (Hu). The Open Fund support from LNM (Xuan and Hu) is also gratefully acknowledged.
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Cited Times:26[WOS]   [WOS Record]     [Related Records in WOS]
Document Type期刊论文
Corresponding AuthorXuan, XC (reprint author), Clemson Univ, Dept Mech Engn, Clemson, SC 29634 USA.
Recommended Citation
GB/T 7714
Kale A,Patel S,Qian SZ,et al. Joule heating effects on reservoir-based dielectrophoresis[J]. Electrophoresis,2014,35(5):721-727.
APA Kale A,Patel S,Qian SZ,Hu GQ,Xuan XC,&Xuan, XC .(2014).Joule heating effects on reservoir-based dielectrophoresis.Electrophoresis,35(5),721-727.
MLA Kale A,et al."Joule heating effects on reservoir-based dielectrophoresis".Electrophoresis 35.5(2014):721-727.
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