Joint detection of tumor markers with imaging ellipsometry biosensor

doi:10.1016/j.tsf.2014.01.043

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	Joint detection of tumor markers with imaging ellipsometry biosensor
	Niu Y(牛宇); Kang TF(康腾飞); Jin G(靳刚); Jin, G (reprint author), 15 Bei Si Huan West Rd, Beijing 100190, Peoples R China.
发表期刊	Thin Solid Films
	2014-11-28
卷号	571 页码:453-462
ISSN	0040-6090
摘要	Tumor marker detection contributes to the early diagnosis of cancers. However, due to the lack of detection specificity, its results cannot act as a direct evidence to confirm cancer occurrence in clinic. Joint detection of tumor markers may improve the detection specificity. As a trial for clinical diagnosis of hepatocellular carcinoma, alpha-fetoprotein, alpha-L-fucosidase and ferritin have been combined and detected with a label-free, phase sensitive and high throughput imaging ellipsometry biosensor (IEB). Eighty-two sera have been quantitatively detected with IEB and the results are in agreement with the clinical standard approaches. Evaluated by receiver operating characteristic analysis, the specificity of joint detection improves remarkably with IEB for hepatocellular carcinoma. It can be foreseen that the joint detection of tumor markers with IEB has a potential for clinical cancer diagnosis. (C) 2014 Elsevier B.V. All rights reserved.
关键词	Joint Detection Tumor Markers Biosensor Imaging Ellipsometry
学科领域	Materials Science ; Physics
DOI	10.1016/j.tsf.2014.01.043
URL	查看原文
收录类别	SCI ; EI
语种	英语
WOS记录号	WOS:000346055200021
关键词[WOS]	CANCER ; VISUALIZATION
WOS研究方向	Materials Science ; Physics
WOS类目	Materials Science, Multidisciplinary ; Materials Science, Coatings & Films ; Physics, Applied ; Physics, Condensed Matter
课题组名称	NML纳米生物光学
论文分区	二类/Q2
引用统计	被引频次：6[WOS] [WOS记录] [WOS相关记录]
文献类型	期刊论文
条目标识符	http://dspace.imech.ac.cn/handle/311007/49490
专题	微重力重点实验室
通讯作者	Jin, G (reprint author), 15 Bei Si Huan West Rd, Beijing 100190, Peoples R China.
推荐引用方式 GB/T 7714	Niu Y,Kang TF,Jin G,et al. Joint detection of tumor markers with imaging ellipsometry biosensor[J]. Thin Solid Films,2014,571:453-462.
APA	Niu Y,Kang TF,Jin G,&Jin, G .(2014).Joint detection of tumor markers with imaging ellipsometry biosensor.Thin Solid Films,571,453-462.
MLA	Niu Y,et al."Joint detection of tumor markers with imaging ellipsometry biosensor".Thin Solid Films 571(2014):453-462.

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IMCAS-J2014-349.pdf（690KB）	期刊论文	出版稿	开放获取	CC BY-NC-SA	浏览请求全文