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Chitosan cushioned air stable single PEGylated phospholipid Mayers
Zhang YB; Chen YY; Ding ZJ; Wang CX; Huang CH; Jin G(靳刚)
Conference Name11th International Congress of the IUPESM. Medical Physics and Biomedical Engineering. World Congress 2009. Micro- and Nanosystems in Active Implants, Biosensors
Conference DateSept. 7-12, 2009
Conference PlaceMunich, Germany
AbstractAir stable single lipid bilayers formation through SUVs fusion methods is still a challenge work. Here soluble LMW chitosan chemically coupled to silicon dioxide surface is cushioned for PEGylated lipid bilayers. Using imaging elUpsometry and spectroscopic elUpsometer, the influence of molar fraction of DSPE-PEG 2000 for lipid bilayers formation and stability is examined. Under the mushroom phase, PEGylated lipid vesicles may aggregate to multiple bilayers; while entering the brush regime of PEG, vesicles can fused into single lipid bilayers. It is demonstrated both the appropriate mole fraction of PEGylaed lipid and hydrophilic polymer cushion are equally critical for achieving air and wash stable single lipid bilayers. Imaging elUpsometry also show the promise as an easy and useful tool for future air stable lipid bilayers based biosensor.
Document Type会议论文
Recommended Citation
GB/T 7714
Zhang YB,Chen YY,Ding ZJ,et al. Chitosan cushioned air stable single PEGylated phospholipid Mayers[C],2009.
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