Joint detection of tumor markers with imaging ellipsometry biosensor

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	Joint detection of tumor markers with imaging ellipsometry biosensor
	Niu Y(牛宇); Kang TF(康腾飞); Jin G(靳刚); gajin@imech.ac.cn
会议录名称	THIN SOLID FILMS
	2014
会议名称	6th International Conference on Spectroscopic Ellipsometry
会议日期	MAY 26-31 2013
会议地点	Kyoto JAPAN
摘要	Tumor marker detection contributes to the early diagnosis of cancers. However due to the lack of detection specificity its results cannot act as a direct evidence to confirm cancer occurrence in clinic. Joint detection of tumor markers may improve the detection specificity. As a trial for clinical diagnosis of hepatocellular carcinoma alpha-fetoprotein alpha-L-fucosidase and ferritin have been combined and detected with a label-free phase sensitive and high throughput imaging ellipsometry biosensor . Eighty-two sera have been quantitatively detected with IEB and the results are in agreement with the clinical standard approaches. Evaluated by receiver operating characteristic analysis the specificity of joint detection improves remarkably with IEB for hepatocellular carcinoma. It can be foreseen that the joint detection of tumor markers with IEB has a potential for clinical cancer diagnosis. 2014 Elsevier B.V. All rights reserved.
关键词	Joint Detection Tumor Markers Biosensor Imaging Ellipsometry
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收录类别	SCI ; CPCI
语种	英语
文献类型	会议论文
条目标识符	http://dspace.imech.ac.cn/handle/311007/55364
专题	微重力重点实验室
通讯作者	gajin@imech.ac.cn
推荐引用方式 GB/T 7714	Niu Y,Kang TF,Jin G,et al. Joint detection of tumor markers with imaging ellipsometry biosensor[C]THIN SOLID FILMS,2014.

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