Joint detection of tumor markers with imaging ellipsometry biosensor | |
Niu Y(牛宇); Kang TF(康腾飞); Jin G(靳刚); gajin@imech.ac.cn | |
Source Publication | THIN SOLID FILMS |
2014 | |
Conference Name | 6th International Conference on Spectroscopic Ellipsometry |
Conference Date | MAY 26-31 2013 |
Conference Place | Kyoto JAPAN |
Abstract | Tumor marker detection contributes to the early diagnosis of cancers. However due to the lack of detection specificity its results cannot act as a direct evidence to confirm cancer occurrence in clinic. Joint detection of tumor markers may improve the detection specificity. As a trial for clinical diagnosis of hepatocellular carcinoma alpha-fetoprotein alpha-L-fucosidase and ferritin have been combined and detected with a label-free phase sensitive and high throughput imaging ellipsometry biosensor . Eighty-two sera have been quantitatively detected with IEB and the results are in agreement with the clinical standard approaches. Evaluated by receiver operating characteristic analysis the specificity of joint detection improves remarkably with IEB for hepatocellular carcinoma. It can be foreseen that the joint detection of tumor markers with IEB has a potential for clinical cancer diagnosis. 2014 Elsevier B.V. All rights reserved. |
Keyword | Joint Detection Tumor Markers Biosensor Imaging Ellipsometry |
URL | 查看原文 |
Indexed By | SCI ; CPCI |
Language | 英语 |
Document Type | 会议论文 |
Identifier | http://dspace.imech.ac.cn/handle/311007/55364 |
Collection | 微重力重点实验室 |
Corresponding Author | gajin@imech.ac.cn |
Recommended Citation GB/T 7714 | Niu Y,Kang TF,Jin G,et al. Joint detection of tumor markers with imaging ellipsometry biosensor[C]THIN SOLID FILMS,2014. |
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Cfp2014-011.pdf(690KB) | 会议论文 | 出版稿 | 开放获取 | CC BY-NC-SA | View Download |
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