A generalized formula for inertial lift on a sphere in microchannels

doi:10.1039/c5lc01522g

IMECH-IR > 非线性力学国家重点实验室

	A generalized formula for inertial lift on a sphere in microchannels
	Liu C; Xue CD; Sun JS; Hu GQ(胡国庆); Hu, GQ (reprint author), Chinese Acad Sci, Inst Mech, Beijing Key Lab Engn Construct & Mechanobiol, State Key Lab Nonlinear Mech, Beijing 100190, Peoples R China.
发表期刊	LAB ON A CHIP
	2016
卷号	16 期号:5 页码:884-892
ISSN	1473-0197
摘要	Inertial microfluidics has been widely used in high-throughput manipulation of particles and cells by hydrodynamic forces, without the aid of externally applied fields. The performance of inertial microfluidic devices largely relies on precise prediction of particle trajectories that are determined by inertial lift acting on particles. The only way to accurately obtain lift forces is by direct numerical simulation (DNS); however, it is burdensome when applied to practical microchannels with complex geometries. Here, we propose a fitting formula for inertial lift on a sphere drawn from DNS data obtained in straight channels. The formula consists of four terms that represent the shear-gradient-induced lift, the wall-induced lift, the slip-shear lift, and the correction of the shear-gradient-induced lift, respectively. Notably, as a function of the parameters of a local flow field, it possesses good adaptability to complex channel geometries. This generalized formula is further implemented in the Lagrangian particle tracking method to realize fast prediction of particle trajectories in two types of widely used microchannels: a long serpentine and a double spiral microchannel, demonstrating its ability to efficiently design and optimize inertial microfluidic devices.
DOI	10.1039/c5lc01522g
URL	查看原文
收录类别	SCI
语种	英语
WOS记录号	WOS:000371009700009
关键词[WOS]	LAGRANGIAN STATISTICS ; FLUID-MECHANICS ; MOTION ; DYNAMICS ; FIBERS ; MICROORGANISMS ; GRADIENT
WOS研究方向	Biochemistry & Molecular Biology ; Chemistry ; Science & Technology - Other Topics
WOS类目	Biochemical Research Methods ; Chemistry, Multidisciplinary ; Nanoscience & Nanotechnology
项目资助者	We thank the National Natural Science Foundation of China (11572335, 11272321, and 91543125) for financial support. We sincerely thank Dr. William D. Henshaw for making the finite-difference code - Overture available to us. The numerical simulations were performed on TianHe-1(A) at the National Supercomputing Center in Tianjin.
课题组名称	LNM微纳米流体力学
论文分区	一类
力学所作者排名	True
引用统计	被引频次：81[WOS] [WOS记录] [WOS相关记录]
文献类型	期刊论文
条目标识符	http://dspace.imech.ac.cn/handle/311007/58663
专题	非线性力学国家重点实验室
通讯作者	Hu, GQ (reprint author), Chinese Acad Sci, Inst Mech, Beijing Key Lab Engn Construct & Mechanobiol, State Key Lab Nonlinear Mech, Beijing 100190, Peoples R China.
推荐引用方式 GB/T 7714	Liu C,Xue CD,Sun JS,et al. A generalized formula for inertial lift on a sphere in microchannels[J]. LAB ON A CHIP,2016,16,5,:884-892.
APA	Liu C,Xue CD,Sun JS,Hu GQ,&Hu, GQ .(2016).A generalized formula for inertial lift on a sphere in microchannels.LAB ON A CHIP,16(5),884-892.
MLA	Liu C,et al."A generalized formula for inertial lift on a sphere in microchannels".LAB ON A CHIP 16.5(2016):884-892.

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