IMECH-IR  > 非线性力学国家重点实验室
A generalized formula for inertial lift on a sphere in microchannels
Liu C; Xue CD; Sun JS; Hu GQ(胡国庆); Hu, GQ (reprint author), Chinese Acad Sci, Inst Mech, Beijing Key Lab Engn Construct & Mechanobiol, State Key Lab Nonlinear Mech, Beijing 100190, Peoples R China.
Source PublicationLAB ON A CHIP
2016
Volume16Issue:5Pages:884-892
ISSN1473-0197
AbstractInertial microfluidics has been widely used in high-throughput manipulation of particles and cells by hydrodynamic forces, without the aid of externally applied fields. The performance of inertial microfluidic devices largely relies on precise prediction of particle trajectories that are determined by inertial lift acting on particles. The only way to accurately obtain lift forces is by direct numerical simulation (DNS); however, it is burdensome when applied to practical microchannels with complex geometries. Here, we propose a fitting formula for inertial lift on a sphere drawn from DNS data obtained in straight channels. The formula consists of four terms that represent the shear-gradient-induced lift, the wall-induced lift, the slip-shear lift, and the correction of the shear-gradient-induced lift, respectively. Notably, as a function of the parameters of a local flow field, it possesses good adaptability to complex channel geometries. This generalized formula is further implemented in the Lagrangian particle tracking method to realize fast prediction of particle trajectories in two types of widely used microchannels: a long serpentine and a double spiral microchannel, demonstrating its ability to efficiently design and optimize inertial microfluidic devices.
DOI10.1039/c5lc01522g
URL查看原文
Indexed BySCI
Language英语
WOS IDWOS:000371009700009
WOS KeywordLAGRANGIAN STATISTICS ; FLUID-MECHANICS ; MOTION ; DYNAMICS ; FIBERS ; MICROORGANISMS ; GRADIENT
WOS Research AreaBiochemistry & Molecular Biology ; Chemistry ; Science & Technology - Other Topics
WOS SubjectBiochemical Research Methods ; Chemistry, Multidisciplinary ; Nanoscience & Nanotechnology
Funding OrganizationWe thank the National Natural Science Foundation of China (11572335, 11272321, and 91543125) for financial support. We sincerely thank Dr. William D. Henshaw for making the finite-difference code - Overture available to us. The numerical simulations were performed on TianHe-1(A) at the National Supercomputing Center in Tianjin.
DepartmentLNM微纳米流体力学
Classification一类
RankingTrue
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Document Type期刊论文
Identifierhttp://dspace.imech.ac.cn/handle/311007/58663
Collection非线性力学国家重点实验室
Corresponding AuthorHu, GQ (reprint author), Chinese Acad Sci, Inst Mech, Beijing Key Lab Engn Construct & Mechanobiol, State Key Lab Nonlinear Mech, Beijing 100190, Peoples R China.
Recommended Citation
GB/T 7714
Liu C,Xue CD,Sun JS,et al. A generalized formula for inertial lift on a sphere in microchannels[J]. LAB ON A CHIP,2016,16(5):884-892.
APA Liu C,Xue CD,Sun JS,Hu GQ,&Hu, GQ .(2016).A generalized formula for inertial lift on a sphere in microchannels.LAB ON A CHIP,16(5),884-892.
MLA Liu C,et al."A generalized formula for inertial lift on a sphere in microchannels".LAB ON A CHIP 16.5(2016):884-892.
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