IMECH-IR  > 国家微重力实验室
Chitosan cushioned air stable single PEGylated phospholipid bilayers
Zhang YB; Chen YY; Ding ZJ; Wang CX; Huang CH; Jin G(靳刚); Jin, G (reprint author), Chinese Acad Sci, Inst Mech, 15 Bei Si Huan W Rd, Beijing 100190, Peoples R China.
Source PublicationMICRO-AND NANOSYSTEMS IN MEDICINE, ACTIVE IMPLANTS, BIOSENSORS
2009
Conference NameWorld Congress on Medical Physics and Biomedical Engineering
Conference DateSEP 07-12, 2009
Conference PlaceMunich, GERMANY
AbstractAir stable single lipid bilayers formation through SUVs fusion methods is still a challenge work. Here soluble LMW chitosan chemically coupled to silicon dioxide surface is cushioned for PEGylated lipid bilayers. Using imaging ellipsometry and spectroscopic ellipsometer, the influence of molar fraction of DSPE-PEG(2000) for lipid bilayers formation and stability is examined. Under the mushroom phase, PEGylated lipid vesicles may aggregate to multiple bilayers; while entering the brush regime of PEG, vesicles can fused into single lipid bilayers. It is demonstrated both the appropriate mole fraction of PEGylaed lipid and hydrophilic polymer cushion are equally critical for achieving air and wash stable single lipid bilayers. Imaging ellipsometry also show the promise as an easy and useful tool for future air stable lipid bilayers based biosensor.
WOS IDWOS:000291667000046
ISBN978-3-642-03886-0
Indexed ByCPCI-S ; EI
Language英语
Citation statistics
Document Type会议论文
Identifierhttp://dspace.imech.ac.cn/handle/311007/58885
Collection国家微重力实验室
Corresponding AuthorJin, G (reprint author), Chinese Acad Sci, Inst Mech, 15 Bei Si Huan W Rd, Beijing 100190, Peoples R China.
Recommended Citation
GB/T 7714
Zhang YB,Chen YY,Ding ZJ,et al. Chitosan cushioned air stable single PEGylated phospholipid bilayers[C]. NEW YORK:SPRINGER,2009.
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