Knowledge Management System of Institue of Mechanics, CAS
Imaging ellipsometry for the visualization of bio-molecular layers | |
Jin G(靳刚)![]() ![]() | |
Source Publication | PROCEEDINGS OF THE 20TH ANNUAL INTERNATIONAL CONFERENCE OF THE IEEE ENGINEERING IN MEDICINE AND BIOLOGY SOCIETY, VOL 20, PTS 1-6: BIOMEDICAL ENGINEERING TOWARDS THE YEAR 2000 AND BEYOND |
1998 | |
Conference Name | 10th Annual International Conference of the IEEE-Engineering-in-Medicine-and-Biology-Society |
Conference Date | OCT 29-NOV 01, 1998 |
Conference Place | HONG KONG, PEOPLES R CHINA |
Abstract | Imaging ellipsometry is presented as a visualization technique to study bio-molecular layers. The layers have become more and more attractive in materials science, especially the layers with the thickness similar to the cellular layers and with the physiological activities are very important in molecular biology and medicine. Normally bio-molecular layers are very thin, which thickness is between sub-nanometer and several tens nanometer. They are transparent in visible range of Light, so that they are recognized as a phase object in physics. Imaging ellipsometry is non-destructive and exhibits a high sensitivity to phase transitions within thin layers. It is capable of imaging local variations in the optical properties such as thickness due to the presence of different surface concentration of bio-molecule or different deposited molecules. Imaging ellipsometry is based on conventional ellipsometry with charge coupled device (CCD) technique. The images are captured with a computer with image processing technique. It has high sensitivity to thickness variation (resolution in the order of angstrom), and high sampling speed (25 pictures with more than 10(5) pixels per second). Although here it had just shown some examples of visualization of bio-molecular layers, it would be possible to show a formation process of bio-molecular layers with a real-time technique. |
WOS ID | WOS:000079210400158 |
ISBN | 0-7803-5164-9 |
Indexed By | CPCI-S |
Language | 英语 |
Citation statistics | |
Document Type | 会议论文 |
Identifier | http://dspace.imech.ac.cn/handle/311007/58973 |
Collection | 力学所知识产出(1956-2008) |
Corresponding Author | Jin, G (reprint author), Chinese Acad Sci, Inst Mech, Beijing 100080, Peoples R China. |
Recommended Citation GB/T 7714 | Jin G,Wang ZH,Meng YH,et al. Imaging ellipsometry for the visualization of bio-molecular layers[C]PROCEEDINGS OF THE 20TH ANNUAL INTERNATIONAL CONFERENCE OF THE IEEE ENGINEERING IN MEDICINE AND BIOLOGY SOCIETY, VOL 20, PTS 1-6: BIOMEDICAL ENGINEERING TOWARDS THE YEAR 2000 AND BEYOND,1998. |
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CPCI-B072.pdf(548KB) | 会议论文 | 开放获取 | CC BY-NC-SA | View Download |
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