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纳米颗粒作为细胞内药物载体的实验研究
王九令; 张璐; 冯强; 孙佳姝; 蒋兴宇; 施兴华
Source Publication中国力学大会-2015论文摘要集
2015
Conference Name中国力学大会-2015
Conference Date2015-08-16
Conference Place中国上海
Abstract利用微流控芯片制备了尺寸、形状、表面物化性质一致的纳米颗粒.此类颗粒结构以磷脂为壳,聚合物为核,中间则是水分子层.通过改变试剂的加入顺序以及调控试剂流速,他们成功地制备出含水量不同的纳米颗粒.通过理论分析以及分子模拟,揭示了刚度调节纳米颗粒进入细胞的力学机制.此项研究表明纳米颗粒的刚度对细胞的内吞起着显著影响,可以用来指导细胞内药物输运载体的设计.
Keyword微流控芯片 物化性质 药物载体 分子层 分子模拟 内吞 理论分析 运载体 力学机制
DepartmentLNM微结构计算力学(筹)
Language中文
Document Type会议论文
Identifierhttp://dspace.imech.ac.cn/handle/311007/59254
Collection非线性力学国家重点实验室
Recommended Citation
GB/T 7714
王九令,张璐,冯强,等. 纳米颗粒作为细胞内药物载体的实验研究[C]中国力学大会-2015论文摘要集,2015.
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