| Multi-layer composite mechanical modeling for the inhomogeneous biofilm mechanical behavior | |
| Wang XL; Han JS; Li K; Wang GQ; Hao MD; Wang, XL (reprint author), Univ Sci & Technol Beijing, Sch Mech Engn, Beijing 100083, Peoples R China.; Wang, XL (reprint author), Harvard Univ, Fac Arts & Sci, Harvard John A Paulson Sch Engn & Appl Sci, Cambridge, MA 02138 USA.; Wang, XL (reprint author), Chinese Acad Sci, LNM, Inst Mech, 15 Bei Si Huan Xi Lu, Beijing 100190, Peoples R China. | |
| Source Publication | JOURNAL OF BIOINFORMATICS AND COMPUTATIONAL BIOLOGY
 |
| 2016 | |
| Volume | 14Issue:4Pages:1650014 |
| ISSN | 0219-7200 |
| Abstract | Experiments showed that bacterial biofilms are heterogeneous, for example, the density, the diffusion coefficient, and mechanical properties of the biofilm are different along the biofilm thickness. In this paper, we establish a multi-layer composite model to describe the biofilm mechanical inhomogeneity based on unified multiple-component cellular automaton (UMCCA) model. By using our model, we develop finite element simulation procedure for biofilm tension experiment. The failure limit and biofilm extension displacement obtained from our model agree well with experimental measurements. This method provides an alternative theory to study the mechanical inhomogeneity in biological materials. |
| Keyword | Biofilm Finite Element Method Multi-layer Composite Mechanical Model Umcca Inhomogeneity |
| DOI | 10.1142/S0219720016500141 |
| URL | 查看原文 |
| Indexed By | SCI |
| Language | 英语 |
| WOS ID | WOS:000384031700003 |
| WOS Keyword | Biofilm ; finite element method ; multi-layer composite mechanical model ; UMCCA ; inhomogeneity |
| WOS Research Area | Biochemistry & Molecular Biology ; Computer Science ; Mathematical & Computational Biology |
| WOS Subject | Biochemical Research Methods ; Computer Science, Interdisciplinary Applications ; Mathematical & Computational Biology |
| Funding Organization | The work was supported by Harvard University, the National Natural Science Foundation of China (Grant No. 11272002), Opening fund of State Key Laboratory of Nonlinear Mechanics, and Beijing Higher Education Young Elite Teacher Project (Grant No. YETP0363). |
| Classification | Q4 |
| Ranking | False |
| Citation statistics | |
| Document Type | 期刊论文 |
| Identifier | http://dspace.imech.ac.cn/handle/311007/59729 |
| Collection | 非线性力学国家重点实验室 |
| Corresponding Author | Wang, XL (reprint author), Univ Sci & Technol Beijing, Sch Mech Engn, Beijing 100083, Peoples R China.; Wang, XL (reprint author), Harvard Univ, Fac Arts & Sci, Harvard John A Paulson Sch Engn & Appl Sci, Cambridge, MA 02138 USA.; Wang, XL (reprint author), Chinese Acad Sci, LNM, Inst Mech, 15 Bei Si Huan Xi Lu, Beijing 100190, Peoples R China. |
| Recommended Citation GB/T 7714 | Wang XL,Han JS,Li K,et al. Multi-layer composite mechanical modeling for the inhomogeneous biofilm mechanical behavior[J]. JOURNAL OF BIOINFORMATICS AND COMPUTATIONAL BIOLOGY,2016,14(4):1650014. |
| APA | Wang XL.,Han JS.,Li K.,Wang GQ.,Hao MD.,...&Wang, XL .(2016).Multi-layer composite mechanical modeling for the inhomogeneous biofilm mechanical behavior.JOURNAL OF BIOINFORMATICS AND COMPUTATIONAL BIOLOGY,14(4),1650014. |
| MLA | Wang XL,et al."Multi-layer composite mechanical modeling for the inhomogeneous biofilm mechanical behavior".JOURNAL OF BIOINFORMATICS AND COMPUTATIONAL BIOLOGY 14.4(2016):1650014. |
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| a2016-089.pdf（998KB） | 期刊论文 | 作者接受稿 | 开放获取 | CC BY-NC-SA | View Download | |
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