| Application of supported phospholipids bilayer bilayers for biosensor based on imaging ellipsometry | |
Chen YY; Zhang YB; Wang CX ; Ding ZJ; Huang CH; Chang WR; Jin G(靳刚); Chang, W. R. (wrchang@sun5.ibp.ac.cn)
| |
| 会议录名称 | IFMBE Proceedings |
| 2009 | |
| 会议名称 | World Congress on Medical Physics and Biomedical Engineering: Micro- and Nanosystems in Medicine, Active Implants, Biosensors |
| 会议日期 | September 7, 2009 - September 12, 2009 |
| 会议地点 | Munich, Germany |
| 摘要 | Application of supported phospholipids bilayers (SPB) is presented for biosensor based on imaging ellipsometry. One SPB is prepared by covalent immobilization of phospholipids monolayer on silicon surface, and followed by adsorption of PEG functionalized phospholipids layer. Another is prepared by adsorption of the mixture of phospholipids and PEG functionalized phospholipids on the hydrophilic silicon surface. Results show that obvious resistance to non-specific protein adsorption on SPB is obtained, and proteins covalently immobilized on the bilayers by the terminal carboxyl group of PEG remain higher bioactivity than that immobilized on silicon surface directly. © 2009 Springer-Verlag. |
| 关键词 | Bi-layer Carboxyl Groups Covalent Immobilization Functionalized Imaging Ellipsometry Microfiuidic Array Non-specific Protein Adsorption Phospholipids Bilayer Silicon Surfaces Supported Phospholipid Bilayers |
| ISBN号 | 9783642038860 |
| URL | 查看原文 |
| 收录类别 | EI |
| 语种 | 英语 |
| 文献类型 | 会议论文 |
| 条目标识符 | http://dspace.imech.ac.cn/handle/311007/60454 |
| 专题 | 微重力重点实验室 |
| 通讯作者 | Chang, W. R. (wrchang@sun5.ibp.ac.cn) |
| 推荐引用方式 GB/T 7714 | Chen YY,Zhang YB,Wang CX,et al. Application of supported phospholipids bilayer bilayers for biosensor based on imaging ellipsometry[C]IFMBE Proceedings,2009. |
| 条目包含的文件 | 下载所有文件 | |||||
| 文件名称/大小 | 文献类型 | 版本类型 | 开放类型 | 使用许可 | ||
| Ca2009-053.pdf（149KB） | 会议论文 | 开放获取 | CC BY-NC-SA | 浏览 下载 | ||
除非特别说明，本系统中所有内容都受版权保护，并保留所有权利。
修改评论