Force spectroscopy of single receptor-ligand bond using an optical trap

IMECH-IR > 微重力重点实验室

	Force spectroscopy of single receptor-ligand bond using an optical trap
	Zhang Y(章燕); Sun GY(孙淦云); Li N(李宁); Huo B(霍波); Lv SQ(吕守芹); Long M(龙勉); Zhang, Y.
会议录名称	2009 Asia Communications and Photonics Conference and Exhibition, ACP 2009
	2009
会议名称	2009 Asia Communications and Photonics Conference and Exhibition, ACP 2009
会议日期	November 2, 2009 - November 6, 2009
会议地点	Shanghai, China
摘要	Here we developed an thermal fluctuation assay using optical trap technique, which enables to visualize consecutive binding-unbinding transition and to unravel the bond dissociation at low spring cosntant and low loading rate. This novel method provided further understandings in monitoring biophysics of receptor-ligand interactions. ©2009 Optical Society of America.
关键词	Bond Dissociation Force Spectroscopy Low Loading Novel Methods Optical Trap Receptor-ligand Bonds Receptor-ligand Interactions Thermal Fluctuations Unbinding Transitions
ISBN号	9781557528773
收录类别	EI
语种	英语
文献类型	会议论文
条目标识符	http://dspace.imech.ac.cn/handle/311007/60461
专题	微重力重点实验室
通讯作者	Zhang, Y.
推荐引用方式 GB/T 7714	Zhang Y,Sun GY,Li N,et al. Force spectroscopy of single receptor-ligand bond using an optical trap[C]2009 Asia Communications and Photonics Conference and Exhibition, ACP 2009,2009.