IMECH-IR  > 非线性力学国家重点实验室
Depth-dependent mechanical characteristics of porcine cornea
Du RQ(杜睿琪); Tian HJ(田晗菁); Xu XH(许向红); Shao YF(邵颖峰); Song F(宋凡); Song, F (reprint author), Chinese Acad Sci, Inst Mech, State Key Lab Nonlinear Mech LNM, Beisihuanxi Rd 15, Beijing 100190, Peoples R China.; Song, F (reprint author), Chinese Acad Sci, Inst Mech, Beijing Key Lab Engn Construct & Mechanobiol, Beisihuanxi Rd 15, Beijing 100190, Peoples R China.
Source PublicationSOFT MATERIALS
2017
Volume15Issue:1Pages:27-33
ISSN1539-445X
AbstractThe biomechanical characteristics of porcine corneal stroma along the depth of cornea in different anatomical orientations were experimentally investigated and quantitatively analyzed. The porcine corneal stroma tested here was cut mechanically into the three layers along the thickness of the cornea for the first time. Based on the convenient uniaxial tensile extensometry, the Young's moduli of each stromal layer in different anatomical orientations were proved to be equal to each other. By virtue of testing the mechanical behaviors of the different layers, the Young's moduli of the stromal layers were found to decrease gradually from the anterior to posterior corneal surface. Thus, the stroma was proved to be mechanically transversely isotropic. Furthermore, based on the analysis of the experimental data, the change of stromal Young's modulus along the depth of the cornea was determined to be linear and equal to - 2.79 +/- 0.967 MPa/mm from the anterior to posterior corneal surface. Finally, the linear gradient characteristic of the stroma was appropriately explained by virtue of stromal microstructures.
KeywordAnisotropy Corneal Stroma Linear Gradient Mechanical Properties Uniaxial Tension Experiment
DOI10.1080/1539445X.2016.1242497
Indexed BySCI ; EI
Language英语
WOS IDWOS:000394659100003
WOS KeywordCOLLAGEN CROSS-LINKING ; BIOMECHANICAL PROPERTIES ; INTRAOCULAR-PRESSURE ; ORGANIZATION ; STROMA ; ARCHITECTURE ; ELASTICITY ; ANTERIOR ; RABBIT
WOS Research AreaMaterials Science
WOS SubjectMaterials Science, Multidisciplinary
Funding OrganizationNational Natural Science Foundations of China [11232013, 11472285]
ClassificationQ3
Ranking1
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Document Type期刊论文
Identifierhttp://dspace.imech.ac.cn/handle/311007/72135
Collection非线性力学国家重点实验室
Corresponding AuthorSong, F (reprint author), Chinese Acad Sci, Inst Mech, State Key Lab Nonlinear Mech LNM, Beisihuanxi Rd 15, Beijing 100190, Peoples R China.; Song, F (reprint author), Chinese Acad Sci, Inst Mech, Beijing Key Lab Engn Construct & Mechanobiol, Beisihuanxi Rd 15, Beijing 100190, Peoples R China.
Recommended Citation
GB/T 7714
Du RQ,Tian HJ,Xu XH,et al. Depth-dependent mechanical characteristics of porcine cornea[J]. SOFT MATERIALS,2017,15(1):27-33.
APA 杜睿琪.,田晗菁.,许向红.,邵颖峰.,宋凡.,...&Song, F .(2017).Depth-dependent mechanical characteristics of porcine cornea.SOFT MATERIALS,15(1),27-33.
MLA 杜睿琪,et al."Depth-dependent mechanical characteristics of porcine cornea".SOFT MATERIALS 15.1(2017):27-33.
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