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Title:
Depth-dependent mechanical characteristics of porcine cornea
Author: Du RQ(杜睿琪); Tian HJ(田晗菁); Xu XH(许向红); Shao YF(邵颖峰); Song F(宋凡)
Source: SOFT MATERIALS
Issued Date: 2017
Volume: 15, Issue:1, Pages:27-33
Abstract: The biomechanical characteristics of porcine corneal stroma along the depth of cornea in different anatomical orientations were experimentally investigated and quantitatively analyzed. The porcine corneal stroma tested here was cut mechanically into the three layers along the thickness of the cornea for the first time. Based on the convenient uniaxial tensile extensometry, the Young's moduli of each stromal layer in different anatomical orientations were proved to be equal to each other. By virtue of testing the mechanical behaviors of the different layers, the Young's moduli of the stromal layers were found to decrease gradually from the anterior to posterior corneal surface. Thus, the stroma was proved to be mechanically transversely isotropic. Furthermore, based on the analysis of the experimental data, the change of stromal Young's modulus along the depth of the cornea was determined to be linear and equal to - 2.79 +/- 0.967 MPa/mm from the anterior to posterior corneal surface. Finally, the linear gradient characteristic of the stroma was appropriately explained by virtue of stromal microstructures.
Keyword: Anisotropy ; corneal stroma ; linear gradient ; mechanical properties ; uniaxial tension experiment
Language: 英语
Indexed Type: SCI ; EI
Corresponding Author: Song, F (reprint author), Chinese Acad Sci, Inst Mech, State Key Lab Nonlinear Mech LNM, Beisihuanxi Rd 15, Beijing 100190, Peoples R China. ; Song, F (reprint author), Chinese Acad Sci, Inst Mech, Beijing Key Lab Engn Construct & Mechanobiol, Beisihuanxi Rd 15, Beijing 100190, Peoples R China.
Correspondent Email: songf@lnm.imech.ac.cn
DOI: 10.1080/1539445X.2016.1242497
DOC Type: Article
WOS Subject: Materials Science, Multidisciplinary
WOS Subject Extended: Materials Science
WOS Keyword Plus: COLLAGEN CROSS-LINKING ; BIOMECHANICAL PROPERTIES ; INTRAOCULAR-PRESSURE ; ORGANIZATION ; STROMA ; ARCHITECTURE ; ELASTICITY ; ANTERIOR ; RABBIT
WOS ID: WOS:000394659100003
ISSN: 1539-445X
Funder: National Natural Science Foundations of China [11232013, 11472285]
Rank: [Du, Ruiqi; Tian, Hanjing; Xu, Xianghong; Shao, Yingfeng; Song, Fan] Chinese Acad Sci, Inst Mech, State Key Lab Nonlinear Mech LNM, Beisihuanxi Rd 15, Beijing 100190, Peoples R China; [Du, Ruiqi; Tian, Hanjing; Xu, Xianghong; Shao, Yingfeng; Song, Fan] Chinese Acad Sci, Inst Mech, Beijing Key Lab Engn Construct & Mechanobiol, Beisihuanxi Rd 15, Beijing 100190, Peoples R China
Classification: Q3
Ranking: 1
Citation statistics:
Content Type: 期刊论文
URI: http://dspace.imech.ac.cn/handle/311007/72135
Appears in Collections:非线性力学国家重点实验室_期刊论文

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Recommended Citation:
Du RQ,Tian HJ,Xu XH,et al. Depth-dependent mechanical characteristics of porcine cornea[J]. SOFT MATERIALS,2017-01-01,15(1):27-33.
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