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Microparticle separation using asymmetrical induced-charge electro-osmotic vortices on an arc-edge-based floating electrode
Chen XM; Ren YK(任玉坤); Hou LK; Feng XS; Jiang TY; Jiang HY
Source PublicationANALYST
2019-09-07
Volume144Issue:17Pages:5150-5163
ISSN0003-2654
Abstract

Five arc-shaped gaps were designed on the bipolar electrode to actuate alternately opposite-direction asymmetrical induced-charge electro-osmosis (AICEO) vortices, and we developed a microfluidic device using such asymmetrical vortices to realize particle separation. When the buoyancy force dominates in the vertical direction, particles stay at the channel bottom, experiencing a left deflection under the vortices in the convex arc areas. In contrast, when the levitation force induced by AICEO vortices overcomes the buoyancy force, particles are elevated to a high level and captured by right vortices, undergoing a right deflection under the vortices in the concave arc areas. Moreover, when particles pass through the concave or convex arc areas every time, their right or left deflections are enlarged gradually and the separation becomes more complete. Remarkably, as the light/small particles at low voltage, heavy/large particles can be elevated to a new high level and undergo right deflection by increasing the voltage. We first explicitly proved the separation principle and analyzed numerically its capability in density- and size-based separation. Depending on the study of the voltage-dependent AICEO characterization of 4 mu m silica and 4 mu m PMMA particles, we experimentally verified the feasibility of our device in density-based separation. According to the investigation of sensitivity to particle size, we separated multi-sized yeast cells to confirm the capability of our device in size-based separation. Finally, we extracted yeast cells from impeding particles, obtaining 96% purity. Additionally, we designed a 500 mu m distance between the focusing and separation region to circumvent the problems caused by electric-field interaction. Our AICEO-based separation method holds potential to serve as a useful tool in transesterification of microalgal lipids to biodiesel and solar cell processing because of its outstanding advantages, such as gentle conditions, contact-free separation, high-sensitivity and high-efficiency separation capability.

DOI10.1039/c9an01230c
Indexed BySCI
Language英语
WOS IDWOS:000483593000009
WOS KeywordMICROFLUIDIC DEVICE ; SIZE SEPARATION ; PARTICLES ; CELLS ; GRADIENT ; FLOW ; MICROCHANNELS ; NANOPARTICLES ; SHEETS ; BLOOD
WOS Research AreaChemistry
WOS SubjectChemistry, Analytical
Funding ProjectNational Natural Science Foundation of China[11672095] ; National Natural Science Foundation of China[11872165] ; National Natural Science Foundation of China[11802078] ; Self-Planned Task of State Key Laboratory of Robotics and System (HIT)[SKLRS201803B] ; Opening fund of State Key Laboratory of Nonlinear Mechanics
Funding OrganizationNational Natural Science Foundation of China ; Self-Planned Task of State Key Laboratory of Robotics and System (HIT) ; Opening fund of State Key Laboratory of Nonlinear Mechanics
Classification二类/Q1
Ranking2
ContributorRpAu: Ren, Yukun
Citation statistics
Document Type期刊论文
Identifierhttp://dspace.imech.ac.cn/handle/311007/79935
Collection非线性力学国家重点实验室
Recommended Citation
GB/T 7714
Chen XM,Ren YK,Hou LK,et al. Microparticle separation using asymmetrical induced-charge electro-osmotic vortices on an arc-edge-based floating electrode[J]. ANALYST,2019,144(17):5150-5163.
APA Chen XM,Ren YK,Hou LK,Feng XS,Jiang TY,&Jiang HY.(2019).Microparticle separation using asymmetrical induced-charge electro-osmotic vortices on an arc-edge-based floating electrode.ANALYST,144(17),5150-5163.
MLA Chen XM,et al."Microparticle separation using asymmetrical induced-charge electro-osmotic vortices on an arc-edge-based floating electrode".ANALYST 144.17(2019):5150-5163.
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