The manipulation of liquid drops could be very promising in space applications, such as fluid management, heat exchangers, life support systems, etc. Colloidal material box is one of a subsystem and payload of SJ-10 satellite, which was designed for studying the aqueous drop control and colloidal assembling in space. Based on space experiment platform (colloid material box), we have carried out the drop manipulation experiment in space successfully by using the hydrophilic/hydrophobic patterned surface technique, and the mechanism of the drop wetting and control on the patterned substrate during drop evaporation have been further studied. In addition, the drying process of the constrained colloidal drops on the patterned surface has been investigated. Through analyzing deposition patterns of both sessile and pendant droplets, we found that the deposition morphology is the result of competition and cooperation interactions of the free setting, the interface shrinkage and the outward capillary flow. Two different regimes for the relative motion between the particles and the interface was proposed: the pursuit regime (sessile droplet) and the meeting regime (pendant droplet), which furthered the theory of particles deposition in drying droplet.