IMECH-IR  > 高温气体动力学国家重点实验室
Magnetic Actuation of Flexible Microelectrode Arrays for Neural Activity Recordings
Gao L1,2; Wang JF1,4; Guan SL1,2; Du MD1,2,6; Wu K(吴坤)5; Xu K1,2; Zou L1,2; Tian HH1; Fang Y1,2,3
Corresponding AuthorFang, Ying(fangy@nanoctr.cn)
Source PublicationNANO LETTERS
2019-11-01
Volume19Issue:11Pages:8032-8039
ISSN1530-6984
AbstractImplantable microelectrodes that can be remotely actuated via external fields are promising tools to interface with biological systems at a high degree of precision. Here, we report the development of flexible magnetic microelectrodes (FM mu Es) that can be remotely actuated by magnetic fields. The FM mu Es consist of flexible microelectrodes integrated with dielectrically encapsulated FeNi (iron-nickel) alloy microactuators. Both magnetic torque- and force-driven actuation of the EM mu Es have been demonstrated. Nanoplatinum-coated FM mu Es have been applied for in vivo recordings of neural activities from peripheral nerves and cerebral cortex of mice. Moreover, owing to their ultrasmall sizes and mechanical compliance with neural tissues, chronically implanted FM mu Es elicited greatly reduced neuronal cell loss in mouse brain compared to conventional stiff probes. The FM mu Es open up a variety of new opportunities for electrically interfacing with biological systems in a controlled and minimally invasive manner.
Keywordflexible microelectrode magnetic actuation nanoscale roughness neural recording inflammatory response
DOI10.1021/acs.nanolett.9b03232
Indexed BySCI ; EI
Language英语
WOS IDWOS:000497259300055
WOS KeywordTISSUE-RESPONSE ; BRAIN-TISSUE ; ELECTRODES ; SYSTEM ; MICROROBOTS ; POTENTIALS ; IMPLANTS ; CORTEX ; CELLS ; FILMS
WOS Research AreaChemistry ; Science & Technology - Other Topics ; Materials Science ; Physics
WOS SubjectChemistry, Multidisciplinary ; Chemistry, Physical ; Nanoscience & Nanotechnology ; Materials Science, Multidisciplinary ; Physics, Applied ; Physics, Condensed Matter
Funding ProjectStrategic Priority Research Program of the Chinese Academy of Sciences[XDB32030100] ; National Natural Science Foundation of China[21790393] ; National Natural Science Foundation of China[21673057] ; Frontier Research Program of the Chinese Academy of Sciences[QYZDB-SSW-SLH044] ; Fabrication Lab at NCNST
Funding OrganizationStrategic Priority Research Program of the Chinese Academy of Sciences ; National Natural Science Foundation of China ; Frontier Research Program of the Chinese Academy of Sciences ; Fabrication Lab at NCNST
Classification一类
Ranking5
ContributorFang, Ying
Citation statistics
Document Type期刊论文
Identifierhttp://dspace.imech.ac.cn/handle/311007/81217
Collection高温气体动力学国家重点实验室
Affiliation1.Natl Ctr Nanosci & Technol, CAS Ctr Excellence Nanosci, CAS Key Lab Biomed Effects Nanomat & Nanosafety, Beijing 100190, Peoples R China;
2.Univ Chinese Acad Sci, Beijing 100049, Peoples R China;
3.Chinese Acad Sci, CAS Ctr Excellence Brain Sci & Intelligence Techn, Shanghai 200031, Peoples R China;
4.Chinese Acad Sci, State Key Labs Transducer Technol, Beijing 100190, Peoples R China;
5.Chinese Acad Sci, Inst Mech, State Key Lab High Temp Gas Dynam, Beijing 100190, Peoples R China;
6.Aalto Univ, Dept Elect & Nanoengn, FI-00076 Espoo, Finland
Recommended Citation
GB/T 7714
Gao L,Wang JF,Guan SL,et al. Magnetic Actuation of Flexible Microelectrode Arrays for Neural Activity Recordings[J]. NANO LETTERS,2019,19(11):8032-8039.
APA Gao L.,Wang JF.,Guan SL.,Du MD.,吴坤.,...&Fang Y.(2019).Magnetic Actuation of Flexible Microelectrode Arrays for Neural Activity Recordings.NANO LETTERS,19(11),8032-8039.
MLA Gao L,et al."Magnetic Actuation of Flexible Microelectrode Arrays for Neural Activity Recordings".NANO LETTERS 19.11(2019):8032-8039.
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