The creep-fatigue fracture behavior of selective laser melting (SLM) AlSi10Mg alloy was studied by conducting in-situ scanning electron microscopy experiments at 500 degrees C. Dwell times of 0, 60 and 120 s were introduced to the tensile-tensile fatigue. The experimental results indicated that the lifetime decreased with lengthening of the dwell time from 0 to 120 s, which closely related to the deformation response behavior of the material. The process of the fracture evolution of the alloy was characterized and analyzed using in-situ scanning electron microscopy images and the fracture morphology. The creep-fatigue fracture mechanism of SLM AlSi10Mg alloy was revealed. Finally, combined with crystal plasticity finite element simulation, the Mises stress, plastic strain and elastic stored energy were used to explain the crack nucleation of SLM AlSi10Mg alloy under fatigue and dwell-fatigue.