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Tyrosine replacement of PSGL-1 reduces association kinetics with P- and L-selectin on the cell membrane 期刊论文
BIOPHYSICAL JOURNAL, 2012, 卷号: 103, 期号: 4, 页码: 777-785
Authors:  Xiao BT(肖波涛);  Tong CF(佟春芳);  Jia XL(贾潇凌);  Guo R(郭瑞);  Lv SQ(吕守芹);  Zhang Y(章燕);  McEver RP;  Zhu C;  Long M(龙勉);  Long, MA;  Chinese Acad Sci, Inst Mech, Key Lab Micrograv, Beijing 100080, Peoples R China.
Adobe PDF(775Kb)  |  Favorite  |  View/Download:1037/274  |  Submit date:2013/01/18
Ligand Binding-kinetics  Glycoprotein Ligand-1  Molecular-dynamics  Adhesion  Sulfation  Proteins  Glycosulfopeptides  Identification  Dissociation  Recognition  
Osteocytic network is more responsive in calcium signaling than osteoblastic network under fluid flow 期刊论文
JOURNAL OF BONE AND MINERAL RESEARCH, 2012, 卷号: 27, 期号: 3, 页码: 563-574
Authors:  Lu XL;  Huo B(霍波);  Chiang V;  Guo XE;  Guo, XE;  Columbia Univ, Dept Biomed Engn, Bone Bioenn Lab, 351 Engn Terrace,Mail Code 8904,1210 Amsterdam Av, New York, NY 10027 USA.
Adobe PDF(467Kb)  |  Favorite  |  View/Download:979/221  |  Submit date:2013/01/18
Osteocytes  Osteoblasts  Cell Network  Mechanotransduction  Fluid Flow  Calcium Signaling  Functional Gap-junctions  Bone Cell Networks  Mc3t3-e1 Osteoblasts  Nitric-oxide  Shear-stress  Prostaglandin Release  Mlo-y4 Osteocytes  Ca2++ Channels  Atp Release  Long Bones  
Molecular dynamics simulation of shear- and stretch-induced dissociation of P-selectin/PSGL-1 complex 期刊论文
BIOPHYSICAL JOURNAL, 2012, 卷号: 102, 期号: 1, 页码: 112-120
Authors:  Kang YY(康英永);  Lv SQ(吕守芹);  Ren P(任鹏);  Huo B(霍波);  Long M(龙勉);  Huo, B (reprint author), Chinese Acad Sci, Inst Mech, Key Lab Micrograv, Natl Micrograv Lab, Beijing 100080, Peoples R China.
Adobe PDF(1143Kb)  |  Favorite  |  View/Download:975/198  |  Submit date:2013/01/18
Selectin Glycoprotein Ligand-1  Granule Membrane-protein  P-selectin  Cell-adhesion  Beta-switch  Endothelial-cells  Catch Bonds  Ib-alpha  Flow  Transition