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中国科学院力学研究所机构知识库
Knowledge Management System of Institue of Mechanics, CAS
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Human vascularized bile duct-on-a chip: a multi-cellular micro-physiological system for studying cholestatic liver disease
期刊论文
BIOFABRICATION, 2024, 卷号: 16, 期号: 1, 页码: 13
Authors:
Du, Yu
;
de Jong, Iris E. M.
;
Gupta, Kapish
;
Waisbourd-Zinman, Orit
;
Har-Zahav, Adi
;
Soroka, Carol J.
;
Boyer, James L.
;
Llewellyn, Jessica
;
Liu, Chengyang
;
Naji, Ali
;
Polacheck, William J.
;
Wells, Rebecca G.
Favorite
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View/Download:281/0
  |  
Submit date:2023/11/28
microfluidic device
cholangiopathy
tissue engineering
organ-on-a-chip
primary sclerosing cholangitis
Direct mechanical exposure initiates hepatocyte proliferation
期刊论文
JHEP REPORTS, 2023, 卷号: 5, 期号: 12, 页码: 13
Authors:
Li, Wang
;
Wu Y(武亿)
;
Hu, Wenhui
;
Zhou J(周瑾)
;
Shu XY(舒芯钰)
;
Zhang XY(张晓宇)
;
Zhang, Ziliang
;
Wu, Huan
;
Du, Yu
;
Lv DY(吕东媛)
;
Lv SQ(吕守芹)
;
Li N(李宁)
;
Long M(龙勉)
Favorite
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View/Download:44/0
  |  
Submit date:2024/01/02
Mechanotransduction
FAK
hepatic sinusoid chip
剪切应力及基质硬度调控肝细胞功能的生物力学机制
学位论文
博士论文,北京: 中国科学院大学, 2023
Authors:
李旺
Adobe PDF(8757Kb)
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View/Download:217/6
  |  
Submit date:2023/06/26
剪切应力
基质硬度
增殖
肝细胞特异性功能
力学转导
力学拉伸调控肝血窦内皮细胞旁分泌及信号转导机制
学位论文
博士论文,北京: 中国科学院大学, 2023
Authors:
武亿
Adobe PDF(31496Kb)
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View/Download:89/3
  |  
Submit date:2023/07/06
肝再生
力学拉伸
肝血窦内皮细胞
旁分泌
信号转导
细胞贯穿孔洞形成与稳定的分子动力学模拟
学位论文
硕士论文,北京: 中国科学院大学, 2023
Authors:
郑植
Adobe PDF(7142Kb)
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View/Download:73/2
  |  
Submit date:2023/06/25
细胞贯穿孔洞
肝血窦内皮细胞
跨内皮细胞大孔
膜融合
粗粒化分 子动力学模拟
膜张力
稳定性
Disturbed Flow-Facilitated Margination and Targeting of Nanodisks Protect against Atherosclerosis
期刊论文
SMALL, 2023, 卷号: 19, 期号: 2, 页码: 10.1002/smll.202204694
Authors:
Zhao, ChuanRong
;
Li, Jingyi
;
Jiang, ZhiTong
;
Zhu, JuanJuan
;
Zhao, JiaNan
;
Yang, QianRu
;
Yao, Weijuan
;
Pang, Wei
;
Li N(李宁)
;
Yu, Miaorong
;
Gan, Yong
;
Zhou, Jing
Adobe PDF(4465Kb)
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View/Download:177/64
  |  
Submit date:2022/12/20
atherosclerosis
decitabine
endothelial inflammation
hemodynamics
nanoparticles
Numerical simulation of flow characteristics in a permeable liver sinusoid with leukocytes
期刊论文
BIOPHYSICAL JOURNAL, 2022, 卷号: 121, 期号: 23, 页码: 4666-4678
Authors:
Chen SB(陈深宝)
;
Zhu, Jingchen
;
Xue J(薛健)
;
Wang, Xiaolong
;
Jing, Peng
;
Zhou, Luwen
;
Cui, Yuhong
;
Wang, Tianhao
;
Gong, Xiaobo
;
Lv SQ(吕守芹)
;
Long M(龙勉)
Adobe PDF(3140Kb)
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Submit date:2023/02/07
Cell senescence alters responses of porcine trabecular meshwork cells to shear stress
期刊论文
FRONTIERS IN CELL AND DEVELOPMENTAL BIOLOGY, 2022, 卷号: 10, 页码: 14
Authors:
Du, Ruotian
;
Li, Dongyan
;
Zhu, Meng
;
Zheng, Lisha
;
Ren, Keli
;
Han, Dong
;
Li L(李龙)
;
Ji, Jing
;
Fan, Yubo
Adobe PDF(2336Kb)
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View/Download:181/29
  |  
Submit date:2023/01/12
shear stress
senescence
trabecular meshwork cell
glaucoma
mechanobiology
Multiscale biomechanics and mechanotransduction from liver fibrosis to cancer
期刊论文
ADVANCED DRUG DELIVERY REVIEWS, 2022, 卷号: 188, 页码: 114448
Authors:
Li N(李宁)
;
Zhang XY(张晓宇)
;
Zhou J(周瑾)
;
Li W(李旺)
;
Shu XY(舒芯钰)
;
Wu Y(武亿)
;
Long M(龙勉)
Adobe PDF(2553Kb)
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  |  
Submit date:2022/10/23
Liver tissue stiffness
Shear stress
Hydrostatic pressure
Hepatocytes
Hepatocellular carcinoma
Liver sinusoidal endothelial cells
Hepatic stellate cells
Mechanotransduction pathways
Mechanomedicine
Drug design and delivery
细胞力学2021年度研究进展
期刊论文
医用生物力学, 2022, 卷号: 37, 期号: 04, 页码: 584-590
Authors:
李宁
;
龙勉
Adobe PDF(490Kb)
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View/Download:208/67
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Submit date:2022/10/17
细胞力学
力学-生物学耦合
力学微环境