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Mechanochemical modeling of neutrophil migration based on four signaling layers, integrin dynamics, and substrate stiffness 期刊论文
BIOMECHANICS AND MODELING IN MECHANOBIOLOGY, 2018, 卷号: 17, 期号: 6, 页码: 1611-1630
Authors:  Feng SL(冯世亮);  Zhou LW(周吕文);  Zhang Y(章燕);  Lv SQ(吕守芹);  Long M(龙勉)
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Chemotaxis  Cytoskeletal remodeling  Mathematical model  Biochemical  Biomechanical  
Binding of intercellular adhesion molecule 1 to beta(2)-integrin regulates distinct cell adhesion processes on hepatic and cerebral endothelium 期刊论文
AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY, 2018, 卷号: 315, 期号: 3, 页码: C409-C421
Authors:  Tong CF(佟春芳);  Zhang Y(章燕);  Lv SQ(吕守芹);  Li N(李宁);  Gong YX(龚一心);  Yang H;  Feng SL;  Du Y;  Huang DD;  Long M(龙勉)
View  |  Adobe PDF(1593Kb)  |  Favorite  |  View/Download:138/13  |  Submit date:2018/10/30
brain  ICAM-1  integrin  kinetics  liver  
不同β2整合素-配体相互作用对中性粒细胞钙响应的影响 会议论文
第十二届全国生物力学学术会议暨第十四届全国生物流变学学术会议会议, 中国陕西西安, 2018年8月17日至21日
Authors:  舒芯钰;  李宁;  龙勉
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性粒细胞  PMN  胞内钙  整合素  
整合素LFA-1/Mac-1与不同配体相互作用的反应动力学及力谱差异 会议论文
第十二届全国生物力学学术会议暨第十四届全国生物流变学学术会议会议, 中国陕西西安, 2018年8月17日至21日
Authors:  李宁;  杨浩;  毛德斌;  王曼柳;  吕守芹;  章燕;  龙勉
View  |  Adobe PDF(163Kb)  |  Favorite  |  View/Download:5/1  |  Submit date:2019/11/21
Mac  LFA-1/Mac-1  反应动力学  PMN  整合素  
Mechanical Strength and Structural Basis of beta(2) Integrin to Mediate Neutrophil Accumulation on Liver Sinusoidal Endothelial Cells: A Study Using Atomic Force Microscopy and Molecular Dynamics Simulations 期刊论文
CMES-COMPUTER MODELING IN ENGINEERING & SCIENCES, 2018, 卷号: 116, 期号: 2, 页码: 263-279
Authors:  Li N(李宁);  Zhang X(张潇);  Li PW;  Yang H;  Tong CF;  Lv SQ(吕守芹);  Zhang Y(章燕);  Ye ZY;  Pan J;  Long M(龙勉)
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Liver sinusoidal endothelial cells  neutrophils  beta(2) integrin  shear flow  mechanical strength  
肝脏疾病中肝细胞损伤的基底刚度调控和中性粒细胞的迁移动力学 学位论文
博士论文,北京: 中国科学院大学, 2018
Authors:  杨浩
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基底刚度  肝细胞损伤  血流剪切  肝血窦  中性粒细胞募集  
基底硬度调控中性粒细胞曳尾结构的力学-生物学耦合机制 学位论文
硕士论文,北京: 中国科学院大学, 2018
Authors:  郭盼
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关键词:基底硬度  中性粒细胞  曳尾结构  Arp2/3复合物  血流剪切  
Ligand-specific binding forces of LFA-1 and Mac-1 in neutrophil adhesion and crawling 期刊论文
MOLECULAR BIOLOGY OF THE CELL, 2018, 卷号: 29, 期号: 4, 页码: 408-418
Authors:  Li N(李宁);  Yang H(杨浩);  Wang ML;  Lv SQ(吕守芹);  Zhang Y(章燕);  Long M(龙勉)
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Salt bridge interactions within the beta(2) integrin alpha(7) helix mediate force-induced binding and shear resistance ability 期刊论文
FEBS JOURNAL, 2018, 卷号: 285, 期号: 2, 页码: 261-274
Authors:  Zhang X(张潇);  Li LD;  Li N(李宁);  Shu XY;  Zhou LW(周吕文);  Lv SQ(吕守芹);  Chen SB;  Mao DB;  Long M(龙勉)
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beta(2) integrin  allostery  conformational stability  force  salt bridge interaction  
Neutrophil adhesion and crawling dynamics on liver sinusoidal endothelial cells under shear flow 期刊论文
EXPERIMENTAL CELL RESEARCH, 2017, 卷号: 351, 期号: 1, 页码: 91-99
Authors:  Yang H(杨浩);  Li N(李宁);  Du Y(杜宇);  Tong CF(佟春芳);  Lv SQ(吕守芹);  Hu JR;  Zhang Y(章燕);  Long M(龙勉);  Long, M (reprint author), Chinese Acad Sci, Inst Mech, Beijing 100190, Peoples R China.
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Neutrophils  Liver Sinusoids  Shear Flow  Adhesive Molecules  Kupffer Cells