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中国科学院力学研究所机构知识库
Knowledge Management System of Institue of Mechanics, CAS
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State Key ... [8]
力学所知识产出(19... [1]
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刘鑫 [9]
赵亚溥 [5]
Guan S [1]
He JW [1]
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The significance of molecular mechanics property to protein evolution
期刊论文
INTERNATIONAL JOURNAL OF DATA MINING AND BIOINFORMATICS, 2013, 卷号: 8, 期号: 1, 页码: 83-91
Authors:
Zhang LM
;
Liu X(刘鑫)
;
Liu, X (reprint author), Chinese Acad Sci, State Key Lab Nonlinear Mech, Inst Mech, 15 Beisihuanxi Rd, Beijing 100190, Peoples R China.
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Submit date:2013/09/09
Hydrophobic Interaction
Protein Evolution
Mechanics Property
Appendant structure plays an important role in amyloidogenic cystatin dimerization prior to domain swapping
期刊论文
Journal of Biomolecular Structure & Dynamics, 2012, 卷号: 30, 期号: 1, 页码: 102-112
Authors:
Yu YY
;
Liu X(刘鑫)
;
He JW
;
Zhang MY
;
Li H
;
Wei DQ
;
Song YT
Adobe PDF(2363Kb)
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Submit date:2012/12/04
Chicken Cystatin
Conformational Disease
Cerebral-hemorrhage
Crystal-structure
Swiss-model
c Variant
Wild-type
Protein
Mutant
Environment
Molecular Dynamic Simulation
Domain Swapping
Appendant Structure
Amyloidosis
Hydrophobic Core
Simulated pathogenic conformational switch regions matched well with the biochemical findings
期刊论文
Journal of Biomedical Informatics., 2010, 卷号: 43, 期号: 3, 页码: 365-375
Authors:
Liu X(刘鑫)
;
Zhao YP(赵亚溥)
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Submit date:2010/05/12
Outline and computational approaches of protein misfolding.
期刊论文
Frontiers of biology, 2010, 期号: 5, 页码: 211
Authors:
Liu X(刘鑫)
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Submit date:2010/05/12
Switch Region for Pathogenic Structural Change in Conformational Disease and Its Prediction
期刊论文
PLoS One, 2010, 卷号: 5, 期号: 1, 页码: e8441
Authors:
Liu X(刘鑫)
;
Zhao YP(赵亚溥)
;
Zhao YP(赵亚溥)
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Submit date:2010/05/12
Generating artificial homologous proteins according to the representative family character in molecular mechanics properties - an attempt in validating an underlying rule of protein evolution
期刊论文
FEBS Letters, 2010, 卷号: 584, 期号: 5, 页码: 1059-1065
Authors:
Liu X(刘鑫)
;
Zhao YP(赵亚溥)
;
Zhao YP(赵亚溥)
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Submit date:2010/05/12
Donut-Shaped Fingerprint In Homologous Polypeptide Relationships-A Topological Feature Related To Pathogenic Structural Changes In Conformational Disease
期刊论文
Journal of Theoretical Biology, 2009, 卷号: 258, 期号: 2, 页码: 294-301
Authors:
Liu X(刘鑫)
;
Zhao YP(赵亚溥)
;
Zhao YP
Adobe PDF(513Kb)
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Submit date:2009/08/03
Homologous Relationship
Polypeptide
Prion Protein
Conformational Disease
Predicting Signal Peptides
State Enzyme-kinetics
Protein-structure
Graphic Rules
Codon Usage
Rate Laws
Evolution
Steady
Model
Prion
A scheme for multiple sequences alignment optimization-an improvement based on family representative mechanics features
期刊论文
Journal of Theoretical Biology, 2009, 卷号: 261, 期号: 4, 页码: 593-597
Authors:
Liu X(刘鑫)
;
Zhao YP(赵亚溥)
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Submit date:2009/12/28
Scoring Scheme
Hydrophobic Interaction
Multiple Sequence Alignment
Homologous Proteins
A combined statistical model for multiple motifs search
期刊论文
Chinese Physics B, 2008, 卷号: 17, 期号: 12, 页码: 4396
Authors:
Gao LF(高丽锋)
;
Liu X(刘鑫)
;
Guan S(官山)
;
Guan S
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Submit date:2010/05/12
Transcription Factor Binding Sites
Motif
Position Weight Matrix