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Distinct binding kinetics of E-, P- and L-selectins to CD44 期刊论文
FEBS JOURNAL, 2022, 页码: 18
作者:  Li LD(李林达);  Ding QH(丁奇寒);  Zhou J(周瑾);  Wu Y(武亿);  Zhang MK(张明坤);  Guo XM;  Long M(龙勉);  Lv SQ(吕守芹)
Adobe PDF(5539Kb)  |  收藏  |  浏览/下载:258/74  |  提交时间:2022/01/12
binding epitope  binding kinetics  CD44  selectin  
Multi-scale molecular dynamics simulations and applications on mechanosensitive proteins of integrins* 期刊论文
CHINESE PHYSICS B, 2021, 卷号: 30, 期号: 3, 页码: 8
作者:  Lv SQ(吕守芹);  Ding QH(丁奇寒);  Zhang MK(张明坤);  Long M(龙勉)
Adobe PDF(834Kb)  |  收藏  |  浏览/下载:257/81  |  提交时间:2021/04/19
molecular dynamics simulations  mechanosensitive protein  allosteric dynamics  integrin  
Conformational folding and disulfide bonding drive distinct stages of protein structure formation 期刊论文
SCIENTIFIC REPORTS, 2018, 卷号: 8, 页码: 1494
作者:  Lv JM;  Lv SQ(吕守芹);  Liu ZP;  Zhang J;  Gao BoX;  Yao ZY;  Wu YX;  Potempa LA.;  Ji SR;  Long M(龙勉);  Wu Y(武毅)
浏览  |  Adobe PDF(5071Kb)  |  收藏  |  浏览/下载:254/69  |  提交时间:2018/07/17
Mechanokinetics of receptor-ligand interactions in cell adhesion 期刊论文
Acta Mechanica Sinica, 2015, 卷号: 31, 期号: 2, 页码: 248-258
作者:  Li N(李宁);  Lv SQ(吕守芹);  Zhang Y(章燕);  Long M(龙勉);  Long, M (reprint author), Chinese Acad Sci, Ctr Biomech & Bioengn, Key Lab Micrograv, Natl Micrograv Lab, Beijing 100190, Peoples R China.
浏览  |  Adobe PDF(809Kb)  |  收藏  |  浏览/下载:523/159  |  提交时间:2015/07/21
Receptor-ligand Interactions  Selectins  Beta(2) Integrins  2d Binding Kinetics  
The impact of N-terminal phosphorylation on LHCII conformation in state transition 期刊论文
Acta Mechanica Sinica, 2014, 卷号: 30, 期号: 3, 页码: 447-456
作者:  Ding JH(丁锦鸿);  Li N(李宁);  Wang ML;  Zhang Y(章燕);  Lv SQ(吕守芹);  Long M(龙勉);  Lu, SQ (reprint author), Chinese Acad Sci, Natl Micrograv Lab, Key Lab Micrograv, Beijing 100190, Peoples R China.
浏览  |  Adobe PDF(746Kb)  |  收藏  |  浏览/下载:680/145  |  提交时间:2014/09/03
State Transition  Lhcii  Phosphorylation  Conformation  
Tyrosine replacement of PSGL-1 reduces association kinetics with P- and L-selectin on the cell membrane 期刊论文
BIOPHYSICAL JOURNAL, 2012, 卷号: 103, 期号: 4, 页码: 777-785
作者:  Xiao BT(肖波涛);  Tong CF(佟春芳);  Jia XL(贾潇凌);  Guo R(郭瑞);  Lv SQ(吕守芹);  Zhang Y(章燕);  McEver RP;  Zhu C;  Long M(龙勉);  Long, MA;  Chinese Acad Sci, Inst Mech, Key Lab Micrograv, Beijing 100080, Peoples R China.
Adobe PDF(775Kb)  |  收藏  |  浏览/下载:1028/265  |  提交时间:2013/01/18
Ligand Binding-kinetics  Glycoprotein Ligand-1  Molecular-dynamics  Adhesion  Sulfation  Proteins  Glycosulfopeptides  Identification  Dissociation  Recognition  
Molecular dynamics simulation of shear- and stretch-induced dissociation of P-selectin/PSGL-1 complex 期刊论文
BIOPHYSICAL JOURNAL, 2012, 卷号: 102, 期号: 1, 页码: 112-120
作者:  Kang YY(康英永);  Lv SQ(吕守芹);  Ren P(任鹏);  Huo B(霍波);  Long M(龙勉);  Huo, B (reprint author), Chinese Acad Sci, Inst Mech, Key Lab Micrograv, Natl Micrograv Lab, Beijing 100080, Peoples R China.
Adobe PDF(1143Kb)  |  收藏  |  浏览/下载:957/195  |  提交时间:2013/01/18
Selectin Glycoprotein Ligand-1  Granule Membrane-protein  P-selectin  Cell-adhesion  Beta-switch  Endothelial-cells  Catch Bonds  Ib-alpha  Flow  Transition  
Advances in Experiments and Modeling in Micro- and Nano-Biomechanics: A Mini Review 期刊论文
Cellular and Molecular Bioengineering, 2011, 卷号: 4, 期号: 3, 页码: 327-339
作者:  Long M(龙勉);  Sato M;  Lim CT;  Wu JH;  Adachi T;  Inoue Y;  Long, M (reprint author), Chinese Acad Sci, Key Lab Micrograv, Ctr Biomech & Bioengn, Inst Mech, Beijing 100190, Peoples R China
Adobe PDF(2481Kb)  |  收藏  |  浏览/下载:1607/337  |  提交时间:2012/04/01
Cellular Mechanics  Molecular Biomechanics  Experimental Techniques  Theoretical Modeling  Computations  Fluid Shear-stress  Endothelial-cell Proliferation  Adhesive Dynamics Simulation  Ligand Binding-kinetics  Glycoprotein-ib-alpha  Von-willebrand-factor  Molecular-dynamics  Mechanical-stress  Beta-switch  2-dimensional Kinetics  
Visualization of Allostery in P-Selectin Lectin Domain Using Md Simulations 期刊论文
PLOS ONE, 2010, 卷号: 5, 期号: 12, 页码: -
作者:  Lv SQ(吕守芹);  Zhang Y(章燕);  Long M(龙勉);  Lu, SQ (reprint author), Chinese Acad Sci, Inst Mech, Key Lab Micrograv, Beijing 100080, Peoples R China.
浏览  |  Adobe PDF(1140Kb)  |  收藏  |  浏览/下载:180/61  |  提交时间:2016/02/01
Molecular Modeling and Affinity Determination of scFv Antibody: Proper Linker Peptide Enhances Its Activity 期刊论文
Annals of Biomedical Engineering, 2010, 卷号: 38, 期号: 2, 页码: 537-549
作者:  Gu X;  Jia XL(贾潇凌);  Feng JN;  Shen BF;  Huang Y;  Geng SS;  Sun YX;  Wang Y;  Li Y;  Long M(龙勉);  Long M(龙勉)
浏览  |  Adobe PDF(616Kb)  |  收藏  |  浏览/下载:1894/627  |  提交时间:2009/12/31
Linker Peptide  Molecular Modeling  Micropipette Adhesion Frequency  Scatchard Analysis  Binding Affinity