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Real-time structural signatures of protein allostery by electrically- and mechanically-coupled sensing 期刊论文
NANO TODAY, 2024, 卷号: 55, 页码: 10
作者:  Zhang, Mingkun;  Zheng, Zhi;  Zhou, Jin;  Ding, Qihan;  Long, Mian;  Lue, Shouqin
收藏  |  浏览/下载：7/0  |  提交时间：2024/03/25
Nanopore sensing  Atomic force microscopy (AFM)  Protein allostery  Steered molecular dynamics (SMD)  Spheroid approximation  
A Novel Human Antibody, HF, against HER2/erb-B2 Obtained by a Computer-Aided Antibody Design Method 期刊论文
ENGINEERING, 2021, 卷号: 7, 期号: 11, 页码: 1566-1576
作者:  Qiao, Chunxia;  Lv, Ming;  Li, Xinying;  Lang, Xiaoling;  Lv SQ(吕守芹);  Long M(龙勉);  Li, Yan;  Geng, Shusheng;  Lin, Zhou;  Shen, Beifen;  Feng, Jiannan
Adobe PDF(4174Kb)  |  收藏  |  浏览/下载：180/29  |  提交时间：2022/02/17
HER2/erb-B2  Human antibody  Computer-aided design  
Mapping the morphological identifiers of distinct conformations via the protein translocation current in nanopores 期刊论文
NANOSCALE, 2021, 卷号: 13, 期号: 12, 页码: 14
作者:  Zhang MK(张明坤);  Chen SB(陈深宝);  Hu JR(胡锦荣);  Ding QH(丁奇寒);  Li LD(李林达);  Lv SQ(吕守芹);  Long M(龙勉)
Adobe PDF(6632Kb)  |  收藏  |  浏览/下载：313/53  |  提交时间：2021/05/17
CD44-配体相互作用的生物力学与功能调控 期刊论文
力学学报, 2021, 卷号: 53, 期号: 02, 页码: 539-553
作者:  李林达;  丁奇寒;  陈深宝;  吕守芹;  龙勉;  郭兴明
Adobe PDF(796Kb)  |  收藏  |  浏览/下载：372/87  |  提交时间：2021/04/19
CD44  选择素  透明质酸  细胞粘附  力学调控  炎症反应  
Impact of real-time shedding on binding kinetics of membrane-remaining L-selectin to PSGL-1 期刊论文
AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY, 2019, 卷号: 316, 期号: 5, 页码: C678-C689
作者:  Peng S(彭爽);  Chen SB(陈深宝);  Li LD(李林达);  Tong CF(佟春芳);  Li N(李宁);  Lv SQ(吕守芹);  Long M(龙勉)
浏览  |  Adobe PDF(2200Kb)  |  收藏  |  浏览/下载：383/198  |  提交时间：2019/12/02
binding kinetics  competitive binding  L-selectin  modeling  real-time shedding  
Mechanical Strength and Structural Basis of beta(2) Integrin to Mediate Neutrophil Accumulation on Liver Sinusoidal Endothelial Cells: A Study Using Atomic Force Microscopy and Molecular Dynamics Simulations 期刊论文
CMES-COMPUTER MODELING IN ENGINEERING & SCIENCES, 2018, 卷号: 116, 期号: 2, 页码: 263-279
作者:  Li N(李宁);  Zhang X(张潇);  Li PW;  Yang H;  Tong CF;  Lv SQ(吕守芹);  Zhang Y(章燕);  Ye ZY;  Pan J;  Long M(龙勉)
浏览  |  Adobe PDF(865Kb)  |  收藏  |  浏览/下载：386/188  |  提交时间：2018/10/30
Liver sinusoidal endothelial cells  neutrophils  beta(2) integrin  shear flow  mechanical strength  
Conformational folding and disulfide bonding drive distinct stages of protein structure formation 期刊论文
SCIENTIFIC REPORTS, 2018, 卷号: 8, 页码: 1494
作者:  Lv JM;  Lv SQ(吕守芹);  Liu ZP;  Zhang J;  Gao BoX;  Yao ZY;  Wu YX;  Potempa LA.;  Ji SR;  Long M(龙勉);  Wu Y(武毅)
浏览  |  Adobe PDF(5071Kb)  |  收藏  |  浏览/下载：256/69  |  提交时间：2018/07/17
Mimicking liver sinusoidal structures and functions using a 3D-configured microfluidic chip 期刊论文
LAB ON A CHIP, 2017, 卷号: 17, 期号: 5, 页码: 782-794
作者:  Du Y(杜宇);  Li N(李宁);  Yang H(杨浩);  Luo CH(罗春花);  Gong YX;  Tong CF(佟春芳);  Gao YX(高宇新);  Lv SQ(吕守芹);  Long M(龙勉);  Long, M (reprint author), Chinese Acad Sci, Key Lab Micrograv, Natl Micrograv Lab, Ctr Biomech & Bioengn, Beijing 100190, Peoples R China.;  Long, M (reprint author), Chinese Acad Sci, Beijing Key Lab Engn Construct & Mech, Inst Mech, Beijing 100190, Peoples R China.;  Long, M (reprint author), Univ Chinese Acad Sci, Sch Engn Sci, Beijing 100049, Peoples R China.
浏览  |  Adobe PDF(6728Kb)  |  收藏  |  浏览/下载：753/489  |  提交时间：2017/07/24
Multi-patterned dynamics of mitochondrial fission and fusion in a living cell 期刊论文
PLOS ONE, 2012, 卷号: 7, 期号: 5, 页码: e19879
作者:  Wang SQ(王世骐);  Xiao WM;  Dan SC(单思聪);  Jiang CS;  Chen M;  Zhang Y(章燕);  Lv SQ(吕守芹);  Chen J(陈娟);  Zhang CM;  Chen Quan;  Long M(龙勉);  Wang, SQ;  Chinese Acad Sci, Natl Micrograv Lab, Key Lab Micrograv, Beijing, Peoples R China.
Adobe PDF(874Kb)  |  收藏  |  浏览/下载：1319/306  |  提交时间：2013/01/18
Mammalian-cells  Yeast  Microtubules  Segregation  Morphology  Apoptosis  Transport  Movement  
分子动力学模拟与分子生物力学 期刊论文
生物物理学报, 2012, 卷号: 28, 期号: 1, 页码: 6-14
作者:  吕守芹;  龙勉
Adobe PDF(378Kb)  |  收藏  |  浏览/下载：2724/572  |  提交时间：2013/01/16
分子动力学模拟  分子生物力学  微观结构动力学  结构-功能关系