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Mechanical strength determines Ca2+ transients triggered by the engagement of beta(2) integrins to their ligands 期刊论文
EXPERIMENTAL CELL RESEARCH, 2020, 卷号: 387, 期号: 2, 页码: 7
作者:  Shu XY(舒芯钰);  Li N(李宁);  Huang DD(黄丹丹);  Zhang Y(章燕);  Lv SQ(吕守芹);  Long M(龙勉)
浏览  |  Adobe PDF(1108Kb)  |  收藏  |  浏览/下载：428/160  |  提交时间：2020/04/07
beta(2) integrin  Ligands  Calcium transients  Bond strength  Mechanotransduction  Shear stress  
Binding of intercellular adhesion molecule 1 to beta(2)-integrin regulates distinct cell adhesion processes on hepatic and cerebral endothelium 期刊论文
AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY, 2018, 卷号: 315, 期号: 3, 页码: C409-C421
作者:  Tong CF(佟春芳);  Zhang Y(章燕);  Lv SQ(吕守芹);  Li N(李宁);  Gong YX(龚一心);  Yang H;  Feng SL;  Du Y;  Huang DD;  Long M(龙勉)
浏览  |  Adobe PDF(1593Kb)  |  收藏  |  浏览/下载：542/266  |  提交时间：2018/10/30
brain  ICAM-1  integrin  kinetics  liver  
Mechanical Strength and Structural Basis of beta(2) Integrin to Mediate Neutrophil Accumulation on Liver Sinusoidal Endothelial Cells: A Study Using Atomic Force Microscopy and Molecular Dynamics Simulations 期刊论文
CMES-COMPUTER MODELING IN ENGINEERING & SCIENCES, 2018, 卷号: 116, 期号: 2, 页码: 263-279
作者:  Li N(李宁);  Zhang X(张潇);  Li PW;  Yang H;  Tong CF;  Lv SQ(吕守芹);  Zhang Y(章燕);  Ye ZY;  Pan J;  Long M(龙勉)
浏览  |  Adobe PDF(865Kb)  |  收藏  |  浏览/下载：380/186  |  提交时间：2018/10/30
Liver sinusoidal endothelial cells  neutrophils  beta(2) integrin  shear flow  mechanical strength  
Ligand-specific binding forces of LFA-1 and Mac-1 in neutrophil adhesion and crawling 期刊论文
MOLECULAR BIOLOGY OF THE CELL, 2018, 卷号: 29, 期号: 4, 页码: 408-418
作者:  Li N(李宁);  Yang H(杨浩);  Wang ML;  Lv SQ(吕守芹);  Zhang Y(章燕);  Long M(龙勉)
浏览  |  Adobe PDF(1832Kb)  |  收藏  |  浏览/下载：392/89  |  提交时间：2018/10/30
Neutrophil adhesion and crawling dynamics on liver sinusoidal endothelial cells under shear flow 期刊论文
EXPERIMENTAL CELL RESEARCH, 2017, 卷号: 351, 期号: 1, 页码: 91-99
作者:  Yang H(杨浩);  Li N(李宁);  Du Y(杜宇);  Tong CF(佟春芳);  Lv SQ(吕守芹);  Hu JR;  Zhang Y(章燕);  Long M(龙勉);  Long, M (reprint author), Chinese Acad Sci, Inst Mech, Beijing 100190, Peoples R China.
浏览  |  Adobe PDF(2025Kb)  |  收藏  |  浏览/下载：663/269  |  提交时间：2017/07/24
Neutrophils  Liver Sinusoids  Shear Flow  Adhesive Molecules  Kupffer Cells  
Mechanokinetics of receptor-ligand interactions in cell adhesion 期刊论文
Acta Mechanica Sinica, 2015, 卷号: 31, 期号: 2, 页码: 248-258
作者:  Li N(李宁);  Lv SQ(吕守芹);  Zhang Y(章燕);  Long M(龙勉);  Long, M (reprint author), Chinese Acad Sci, Ctr Biomech & Bioengn, Key Lab Micrograv, Natl Micrograv Lab, Beijing 100190, Peoples R China.
浏览  |  Adobe PDF(809Kb)  |  收藏  |  浏览/下载：521/158  |  提交时间：2015/07/21
Receptor-ligand Interactions  Selectins  Beta(2) Integrins  2d Binding Kinetics  
β2整合素LFA-1/Mac-1功能差异的分子作用机制 会议论文
第十一届全国生物力学学术会议暨第十三届全国生物流变学学术会议会议, 中国山西太原, 2015-10-10
作者:  李宁;  毛德斌;  佟春芳;  杨浩;  王曼柳;  吕守芹;  章燕;  龙勉
浏览  |  Adobe PDF(139Kb)  |  收藏  |  浏览/下载：259/69  |  提交时间：2016/08/16
功能差异  血管内皮细胞  Lfa-1/mac-1  Neutrophil  整合素  Macrophage  炎症反应  分子作用机制  动力学模拟  Intercellular  
Distinct binding affinities of Mac-1 and LFA-1 in neutrophil activation 期刊论文
JOURNAL OF IMMUNOLOGY, 2013, 卷号: 190, 期号: 8, 页码: 4371-4381
作者:  Li N(李宁);  Mao DB(毛德斌);  Lv SQ(吕守芹);  Tong CF(佟春芳);  Zhang Y(章燕);  Long M(龙勉);  Long, M (reprint author), Chinese Acad Sci, Inst Mech, Natl Micrograv Lab, Key Lab Micrograv, 15 North 4th Ring Rd, Beijing 100190, Peoples R China.
Adobe PDF(777Kb)  |  收藏  |  浏览/下载：1400/352  |  提交时间：2013/05/21
Fluid flow-induced calcium response in early or late differentiated osteoclasts 期刊论文
ANNALS OF BIOMEDICAL ENGINEERING, 2012, 卷号: 40, 期号: 9, 页码: 1874-1883
作者:  Li P(李平);  Hu M(胡漫);  Sun SJ(孙树津);  Zhang Y(章燕);  Gao YX(高宇欣);  Long M(龙勉);  Huo B(霍波);  Zhang D;  Huo, B;  Chinese Acad Sci, Inst Mech, Ctr Biomech & Bioengn, Key Lab Micrograv, 15 N 4th Ring Rd, Beijing 100190, Peoples R China.
Adobe PDF(887Kb)  |  收藏  |  浏览/下载：1213/346  |  提交时间：2013/01/18
Osteoclasts  Fluid Shear Stress  Calcium Oscillation  Induction Time  Differentiation  Mechanical Strain  Rat Osteoclasts  Bone-resorption  Activation  Expression  Cells  Ca2++  
Spreading of human neutrophils on an ICAM-1-immobilized substrate under shear flow 期刊论文
CHINESE SCIENCE BULLETIN, 2012, 卷号: 57, 期号: 7, 页码: 769-775
作者:  Zhan DY(展冬颖);  Zhang Y(章燕);  Long M(龙勉);  Long, MA;  Chinese Acad Sci, Inst Mech, Key Lab Micrograv, Natl Micrograv Lab, Beijing 100190, Peoples R China.
Adobe PDF(685Kb)  |  收藏  |  浏览/下载：964/226  |  提交时间：2013/01/18
Neutrophil  Spreading  Beta 2 Integrin  Icam-1  Shear Stress  Cell-surface Adhesion  L-selectin  Polymorphonuclear Leukocytes  Endothelial-cells  Rolling Adhesions  P-selectin  Integrin  Affinity  Stress  Icam-1