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Potential Roles of YAP/TAZ Mechanotransduction in Spaceflight-Induced Liver Dysfunction 期刊论文
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES, 2023, 卷号: 24, 期号: 3, 页码: 20
作者:  Li W(李旺);  Shu XY(舒芯钰);  Zhang XY(张晓宇);  Zhang ZL(张子良);  Sun SJ(孙树津);  Li N(李宁);  Long M(龙勉)
Adobe PDF(1498Kb)  |  收藏  |  浏览/下载:117/0  |  提交时间:2023/03/20
microgravity  liver metabolism  mechanosensing  cytoskeleton  nuclear deformation  phase separation  
Distinct binding kinetics of E-, P- and L-selectins to CD44 期刊论文
FEBS JOURNAL, 2022, 页码: 18
作者:  Li LD(李林达);  Ding QH(丁奇寒);  Zhou J(周瑾);  Wu Y(武亿);  Zhang MK(张明坤);  Guo XM;  Long M(龙勉);  Lv SQ(吕守芹)
Adobe PDF(5539Kb)  |  收藏  |  浏览/下载:261/74  |  提交时间:2022/01/12
binding epitope  binding kinetics  CD44  selectin  
Gravity-Vector Induces Mechanical Remodeling of rMSCs via Combined Substrate Stiffness and Orientation 期刊论文
FRONTIERS IN BIOENGINEERING AND BIOTECHNOLOGY, 2022, 卷号: 9, 页码: 14
作者:  Zhang C(张晨);  Lv DY(吕东媛);  Zhang F(张帆);  Wu Y(武亿);  Zheng L(郑鲁);  Zhang XY(张晓宇);  Li Z(李展);  Sun SJ(孙树津);  龙勉Mian
Adobe PDF(3580Kb)  |  收藏  |  浏览/下载:148/45  |  提交时间:2022/05/17
substrate stiffness  orientation  mechanosensing  nucleus translocation  cytoskeletal remodeling  focal adhesion complex reorganization  cellular morphology  
Two Complementary Signaling Pathways Depict Eukaryotic Chemotaxis: A Mechanochemical Coupling Model 期刊论文
FRONTIERS IN CELL AND DEVELOPMENTAL BIOLOGY, 2021, 卷号: 9, 页码: 12
作者:  Zhou LW(周吕文);  Feng SL(冯世亮);  Li L(李龙);  Lv SQ(吕守芹);  Zhang Y(章燕);  Long M(龙勉)
Adobe PDF(2763Kb)  |  收藏  |  浏览/下载:211/41  |  提交时间:2022/01/13
chemotaxis  cytoskeletal remodeling  mathematical model  biochemical  biomechanical  
Plakophilin-2 truncating variants impair cardiac contractility by disrupting sarcomere stability and organization 期刊论文
SCIENCE ADVANCES, 2021, 卷号: 7, 期号: 42, 页码: 14
作者:  Zhang, KH;  Cloonan, PE.;  Sundaram, S;  Liu F(刘峰);  Das, SL;  Ewoldt, JK;  Bays, JL;  Tomp, S;  Toepfer, CN;  Marsiglia, JDC;  Gorham, J;  Reichart, D;  Eyckmans, J;  Seidman, JG;  Seidman, CE;  Chen, CS
Adobe PDF(1131Kb)  |  收藏  |  浏览/下载:234/56  |  提交时间:2021/11/15
Interplay Between Receptor-Ligand Binding and Lipid Domain Formation Depends on the Mobility of Ligands in Cell-Substrate Adhesion 期刊论文
FRONTIERS IN MOLECULAR BIOSCIENCES, 2021, 卷号: 8, 页码: 9
作者:  Li L(李龙);  Wang XH(王小环);  Wu, Helong;  Shao YF(邵颖峰);  Wu, Huaping;  Song F(宋凡)
Adobe PDF(1678Kb)  |  收藏  |  浏览/下载:248/54  |  提交时间:2021/05/31
cell adhesion  receptor-ligand binding  nanoscale lipid cluster  ligand mobility  phase separation  binding constant  
Mechanotransduction of liver sinusoidal endothelial cells under varied mechanical stimuli 期刊论文
ACTA MECHANICA SINICA, 2021, 页码: 17
作者:  Shu XY(舒芯钰);  Li N(李宁);  Wu Y(武亿);  Li W(李旺);  Zhang XY(张晓宇);  Li PW(李培文);  Lv DY(吕东媛);  Lv SQ(吕守芹);  Long M(龙勉)
Adobe PDF(1359Kb)  |  收藏  |  浏览/下载:368/101  |  提交时间:2021/05/06
Liver sinusoidal endothelial cell  Shear stress  Mechanical stretch  Extracellular matrix  Stiffness  
Mechanomics analysis of hESCs under combined mechanical shear, stretch, and compression 期刊论文
BIOMECHANICS AND MODELING IN MECHANOBIOLOGY, 2020, 页码: 18
作者:  Zhang F(张帆);  Wang JW(王家文);  Lv DY(吕东媛);  Zheng L(郑璐);  Shang GB(上官冰);  Gao YX(高宇欣);  Wu Y(武亿);  Long M(龙勉)
Adobe PDF(8050Kb)  |  收藏  |  浏览/下载:309/167  |  提交时间:2020/10/23
Mechanomics  hESCs  iTRAQ  GSEA  WGCNA  
Flow field analyses of a porous membrane-separated, double-layered microfluidic chip for cell co-culture 期刊论文
ACTA MECHANICA SINICA, 2020, 页码: 14
作者:  Chen SB(陈深宝);  Xue J(薛健);  Hu JR(胡锦荣);  Ding QH(丁奇寒);  Zhou LW(周吕文);  Feng SL(冯世亮);  Cui YH;  Lv SQ(吕守芹);  Long M(龙勉)
Adobe PDF(5919Kb)  |  收藏  |  浏览/下载:279/127  |  提交时间:2020/08/26
Immersed boundary method  Porous membrane  Wall shear stress  Penetration velocity  Microfluidic chip  
Flow-enhanced priming of hESCs through H2B acetylation and chromatin decondensation 期刊论文
STEM CELL RESEARCH & THERAPY, 2019, 卷号: 10, 期号: 1, 页码: 16
作者:  Wang JW(王家文);  Wu Y(武亿);  Zhang X(张潇);  Zhang F(张帆);  Lv DY(吕东媛);  Shang GB(上官冰);  Gao YX(高宇欣);  Long M(龙勉)
浏览  |  Adobe PDF(2406Kb)  |  收藏  |  浏览/下载:217/67  |  提交时间:2020/03/11
Embryonic stem cell  Fluid shear mechanomics  Nuclear spreading  Histone acetylation  Chromatin decondensation