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中国科学院力学研究所机构知识库
Knowledge Management System of Institue of Mechanics, CAS
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微重力重点实验室 [42]
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Direct mechanical exposure initiates hepatocyte proliferation
期刊论文
JHEP REPORTS, 2023, 卷号: 5, 期号: 12, 页码: 13
Authors:
Li, Wang
;
Wu Y(武亿)
;
Hu, Wenhui
;
Zhou J(周瑾)
;
Shu XY(舒芯钰)
;
Zhang XY(张晓宇)
;
Zhang, Ziliang
;
Wu, Huan
;
Du, Yu
;
Lv DY(吕东媛)
;
Lv SQ(吕守芹)
;
Li N(李宁)
;
Long M(龙勉)
Favorite
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View/Download:44/0
  |  
Submit date:2024/01/02
Mechanotransduction
FAK
hepatic sinusoid chip
Biomechanics in liver regeneration after partial hepatectomy
期刊论文
FRONTIERS IN BIOENGINEERING AND BIOTECHNOLOGY, 2023, 卷号: 11, 页码: 1165651
Authors:
Wu Y(武亿)
;
Li N(李宁)
;
Shu XY(舒芯钰)
;
Li W(李旺)
;
Zhang XY(张晓宇)
;
Lv DY(吕东媛)
;
Long M(龙勉)
Favorite
  |  
View/Download:59/0
  |  
Submit date:2023/07/17
liver regeneration
partial hepatectomy
hemodynamics
mechanical loading
mechanotransduction
Receptor-Ligand Binding: Effect of Mechanical Factors
期刊论文
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES, 2023, 卷号: 24, 期号: 10, 页码: 9062
Authors:
Du, Ruotian
;
Li L(李龙)
;
Ji, Jing
;
Fan, Yubo
Favorite
  |  
View/Download:35/0
  |  
Submit date:2023/06/15
receptor-ligand binding
tension
shear stress
stretch
compression
substrate stiffness
biomechanics
mechanotransduction
Potential Roles of YAP/TAZ Mechanotransduction in Spaceflight-Induced Liver Dysfunction
期刊论文
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES, 2023, 卷号: 24, 期号: 3, 页码: 20
Authors:
Li W(李旺)
;
Shu XY(舒芯钰)
;
Zhang XY(张晓宇)
;
Zhang ZL(张子良)
;
Sun SJ(孙树津)
;
Li N(李宁)
;
Long M(龙勉)
Favorite
  |  
View/Download:113/0
  |  
Submit date:2023/03/20
microgravity
liver metabolism
mechanosensing
cytoskeleton
nuclear deformation
phase separation
Matrix stiffness exacerbates the proinflammatory responses of vascular smooth muscle cell through the DDR1-DNMT1 mechanotransduction axis
期刊论文
BIOACTIVE MATERIALS, 2022, 卷号: 17, 页码: 406-424
Authors:
Wang, Jin
;
Xie, Si-an
;
Li N(李宁)
;
Zhang, Tao
;
Yao, Weijuan
;
Zhao, Hucheng
;
Pang, Wei
;
Han, Lili
;
Liu, Jiayu
;
Zhou, Jing
Adobe PDF(21819Kb)
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View/Download:268/23
  |  
Submit date:2022/06/10
Matrix stiffness
Inflammation
DDR1
DNMT1
Mechanotransduction
Multiscale biomechanics and mechanotransduction from liver fibrosis to cancer
期刊论文
ADVANCED DRUG DELIVERY REVIEWS, 2022, 卷号: 188, 页码: 114448
Authors:
Li N(李宁)
;
Zhang XY(张晓宇)
;
Zhou J(周瑾)
;
Li W(李旺)
;
Shu XY(舒芯钰)
;
Wu Y(武亿)
;
Long M(龙勉)
Adobe PDF(2553Kb)
  |  
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  |  
View/Download:301/80
  |  
Submit date:2022/10/23
Liver tissue stiffness
Shear stress
Hydrostatic pressure
Hepatocytes
Hepatocellular carcinoma
Liver sinusoidal endothelial cells
Hepatic stellate cells
Mechanotransduction pathways
Mechanomedicine
Drug design and delivery
Two Complementary Signaling Pathways Depict Eukaryotic Chemotaxis: A Mechanochemical Coupling Model
期刊论文
FRONTIERS IN CELL AND DEVELOPMENTAL BIOLOGY, 2021, 卷号: 9, 页码: 12
Authors:
Zhou LW(周吕文)
;
Feng SL(冯世亮)
;
Li L(李龙)
;
Lv SQ(吕守芹)
;
Zhang Y(章燕)
;
Long M(龙勉)
Adobe PDF(2763Kb)
  |  
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View/Download:197/37
  |  
Submit date:2022/01/13
chemotaxis
cytoskeletal remodeling
mathematical model
biochemical
biomechanical
Influence of microflow on hepatic sinusoid blood flow and red blood cell deformation
期刊论文
BIOPHYSICAL JOURNAL, 2021, 卷号: 120, 期号: 21, 页码: 4859-4873
Authors:
Wang, Tianhao
;
Lv SQ(吕守芹)
;
Hao, Yinjing
;
Su, Zinan
;
Long M(龙勉)
;
Cui, Yuhong
Adobe PDF(3057Kb)
  |  
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  |  
View/Download:169/28
  |  
Submit date:2022/01/12
Hepatic differentiation of human embryonic stem cells by coupling substrate stiffness and microtopography
期刊论文
BIOMATERIALS SCIENCE, 2021, 页码: 15
Authors:
Luo CH(罗春花)
;
Lv DY(吕东媛)
;
Zheng L(郑鲁)
;
Zhang F(张帆)
;
Zhang X(张潇)
;
Lv SQ(吕守芹)
;
Zhang C(张晨)
;
Jia Xiaohua
;
Shu XY(舒芯钰)
;
Li PW(李培文)
;
Li Z(李展)
;
Long M(龙勉)
Adobe PDF(7505Kb)
  |  
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  |  
View/Download:289/149
  |  
Submit date:2021/05/17
Interplay Between Receptor-Ligand Binding and Lipid Domain Formation Depends on the Mobility of Ligands in Cell-Substrate Adhesion
期刊论文
FRONTIERS IN MOLECULAR BIOSCIENCES, 2021, 卷号: 8, 页码: 9
Authors:
Li L(李龙)
;
Wang XH(王小环)
;
Wu, Helong
;
Shao YF(邵颖峰)
;
Wu, Huaping
;
Song F(宋凡)
Adobe PDF(1678Kb)
  |  
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View/Download:239/52
  |  
Submit date:2021/05/31
cell adhesion
receptor-ligand binding
nanoscale lipid cluster
ligand mobility
phase separation
binding constant