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The significance of molecular mechanics property to protein evolution 期刊论文
INTERNATIONAL JOURNAL OF DATA MINING AND BIOINFORMATICS, 2013, 卷号: 8, 期号: 1, 页码: 83-91
作者:  Zhang LM;  Liu X(刘鑫);  Liu, X (reprint author), Chinese Acad Sci, State Key Lab Nonlinear Mech, Inst Mech, 15 Beisihuanxi Rd, Beijing 100190, Peoples R China.
Adobe PDF(102Kb)  |  收藏  |  浏览/下载：470/178  |  提交时间：2013/09/09
Hydrophobic Interaction  Protein Evolution  Mechanics Property  
Appendant structure plays an important role in amyloidogenic cystatin dimerization prior to domain swapping 期刊论文
Journal of Biomolecular Structure & Dynamics, 2012, 卷号: 30, 期号: 1, 页码: 102-112
作者:  Yu YY;  Liu X(刘鑫);  He JW;  Zhang MY;  Li H;  Wei DQ;  Song YT
Adobe PDF(2363Kb)  |  收藏  |  浏览/下载：810/304  |  提交时间：2012/12/04
Chicken Cystatin  Conformational Disease  Cerebral-hemorrhage  Crystal-structure  Swiss-model  c Variant  Wild-type  Protein  Mutant  Environment  Molecular Dynamic Simulation  Domain Swapping  Appendant Structure  Amyloidosis  Hydrophobic Core  
Outline and computational approaches of protein misfolding. 期刊论文
Frontiers of biology, 2010, 期号: 5, 页码: 211
作者:  Liu X(刘鑫)
Adobe PDF(1349Kb)  |  收藏  |  浏览/下载：684/190  |  提交时间：2010/05/12
Switch Region for Pathogenic Structural Change in Conformational Disease and Its Prediction 期刊论文
PLoS One, 2010, 卷号: 5, 期号: 1, 页码: e8441
作者:  Liu X(刘鑫);  Zhao YP(赵亚溥);  Zhao YP(赵亚溥)
Adobe PDF(670Kb)  |  收藏  |  浏览/下载：904/202  |  提交时间：2010/05/12
Generating artificial homologous proteins according to the representative family character in molecular mechanics properties - an attempt in validating an underlying rule of protein evolution 期刊论文
FEBS Letters, 2010, 卷号: 584, 期号: 5, 页码: 1059-1065
作者:  Liu X(刘鑫);  Zhao YP(赵亚溥);  Zhao YP(赵亚溥)
Adobe PDF(895Kb)  |  收藏  |  浏览/下载：738/206  |  提交时间：2010/05/12
Donut-Shaped Fingerprint In Homologous Polypeptide Relationships-A Topological Feature Related To Pathogenic Structural Changes In Conformational Disease 期刊论文
Journal of Theoretical Biology, 2009, 卷号: 258, 期号: 2, 页码: 294-301
作者:  Liu X(刘鑫);  Zhao YP(赵亚溥);  Zhao YP
Adobe PDF(513Kb)  |  收藏  |  浏览/下载：723/163  |  提交时间：2009/08/03
Homologous Relationship  Polypeptide  Prion Protein  Conformational Disease  Predicting Signal Peptides  State Enzyme-kinetics  Protein-structure  Graphic Rules  Codon Usage  Rate Laws  Evolution  Steady  Model  Prion  
A scheme for multiple sequences alignment optimization-an improvement based on family representative mechanics features 期刊论文
Journal of Theoretical Biology, 2009, 卷号: 261, 期号: 4, 页码: 593-597
作者:  Liu X(刘鑫);  Zhao YP(赵亚溥)
Adobe PDF(493Kb)  |  收藏  |  浏览/下载：642/158  |  提交时间：2009/12/28
Scoring Scheme  Hydrophobic Interaction  Multiple Sequence Alignment  Homologous Proteins