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Real-time structural signatures of protein allostery by electrically- and mechanically-coupled sensing 期刊论文
NANO TODAY, 2024, 卷号: 55, 页码: 10
作者:  Zhang, Mingkun;  Zheng, Zhi;  Zhou, Jin;  Ding, Qihan;  Long, Mian;  Lue, Shouqin
收藏  |  浏览/下载:3/0  |  提交时间:2024/03/25
Nanopore sensing  Atomic force microscopy (AFM)  Protein allostery  Steered molecular dynamics (SMD)  Spheroid approximation  
Distinct binding kinetics of E-, P- and L-selectins to CD44 期刊论文
FEBS JOURNAL, 2022, 页码: 18
作者:  Li LD(李林达);  Ding QH(丁奇寒);  Zhou J(周瑾);  Wu Y(武亿);  Zhang MK(张明坤);  Guo XM;  Long M(龙勉);  Lv SQ(吕守芹)
Adobe PDF(5539Kb)  |  收藏  |  浏览/下载:256/74  |  提交时间:2022/01/12
binding epitope  binding kinetics  CD44  selectin  
Plakophilin-2 truncating variants impair cardiac contractility by disrupting sarcomere stability and organization 期刊论文
SCIENCE ADVANCES, 2021, 卷号: 7, 期号: 42, 页码: 14
作者:  Zhang, KH;  Cloonan, PE.;  Sundaram, S;  Liu F(刘峰);  Das, SL;  Ewoldt, JK;  Bays, JL;  Tomp, S;  Toepfer, CN;  Marsiglia, JDC;  Gorham, J;  Reichart, D;  Eyckmans, J;  Seidman, JG;  Seidman, CE;  Chen, CS
Adobe PDF(1131Kb)  |  收藏  |  浏览/下载:232/56  |  提交时间:2021/11/15
E-selectin negatively regulates polymorphonuclear neutrophil transmigration through altered endothelial junction integrity 期刊论文
FASEB JOURNAL, 2021, 卷号: 35, 期号: 5, 页码: 15
作者:  Huang DD(黄丹丹);  Ding QH(丁奇寒);  Chen SB(陈深宝);  Lv SQ(吕守芹);  Zhang Y(章燕);  Long M(龙勉)
Adobe PDF(2008Kb)  |  收藏  |  浏览/下载:252/72  |  提交时间:2021/08/03
cytoskeletal remodeling  endothelial integrity  E-selectin  neutrophil  transmigration  
Mapping the morphological identifiers of distinct conformations via the protein translocation current in nanopores 期刊论文
NANOSCALE, 2021, 卷号: 13, 期号: 12, 页码: 14
作者:  Zhang MK(张明坤);  Chen SB(陈深宝);  Hu JR(胡锦荣);  Ding QH(丁奇寒);  Li LD(李林达);  Lv SQ(吕守芹);  Long M(龙勉)
Adobe PDF(6632Kb)  |  收藏  |  浏览/下载:307/50  |  提交时间:2021/05/17
Mechanotransduction of liver sinusoidal endothelial cells under varied mechanical stimuli 期刊论文
ACTA MECHANICA SINICA, 2021, 页码: 17
作者:  Shu XY(舒芯钰);  Li N(李宁);  Wu Y(武亿);  Li W(李旺);  Zhang XY(张晓宇);  Li PW(李培文);  Lv DY(吕东媛);  Lv SQ(吕守芹);  Long M(龙勉)
Adobe PDF(1359Kb)  |  收藏  |  浏览/下载:365/101  |  提交时间:2021/05/06
Liver sinusoidal endothelial cell  Shear stress  Mechanical stretch  Extracellular matrix  Stiffness  
Mechanically Regulated Outside-In Activation of an I-Domain-Containing Integrin 期刊论文
BIOPHYSICAL JOURNAL, 2020, 卷号: 119, 期号: 5, 页码: 966-977
作者:  Mao DB(毛德斌);  Lv SQ(吕守芹);  Zhang X(张潇);  Long M(龙勉)
Adobe PDF(2480Kb)  |  收藏  |  浏览/下载:224/61  |  提交时间:2020/10/29
Mechanomics analysis of hESCs under combined mechanical shear, stretch, and compression 期刊论文
BIOMECHANICS AND MODELING IN MECHANOBIOLOGY, 2020, 页码: 18
作者:  Zhang F(张帆);  Wang JW(王家文);  Lv DY(吕东媛);  Zheng L(郑璐);  Shang GB(上官冰);  Gao YX(高宇欣);  Wu Y(武亿);  Long M(龙勉)
Adobe PDF(8050Kb)  |  收藏  |  浏览/下载:308/166  |  提交时间:2020/10/23
Mechanomics  hESCs  iTRAQ  GSEA  WGCNA  
Flow field analyses of a porous membrane-separated, double-layered microfluidic chip for cell co-culture 期刊论文
ACTA MECHANICA SINICA, 2020, 页码: 14
作者:  Chen SB(陈深宝);  Xue J(薛健);  Hu JR(胡锦荣);  Ding QH(丁奇寒);  Zhou LW(周吕文);  Feng SL(冯世亮);  Cui YH;  Lv SQ(吕守芹);  Long M(龙勉)
Adobe PDF(5919Kb)  |  收藏  |  浏览/下载:276/124  |  提交时间:2020/08/26
Immersed boundary method  Porous membrane  Wall shear stress  Penetration velocity  Microfluidic chip  
Mechanical strength determines Ca2+ transients triggered by the engagement of beta(2) integrins to their ligands 期刊论文
EXPERIMENTAL CELL RESEARCH, 2020, 卷号: 387, 期号: 2, 页码: 7
作者:  Shu XY(舒芯钰);  Li N(李宁);  Huang DD(黄丹丹);  Zhang Y(章燕);  Lv SQ(吕守芹);  Long M(龙勉)
浏览  |  Adobe PDF(1108Kb)  |  收藏  |  浏览/下载:428/160  |  提交时间:2020/04/07
beta(2) integrin  Ligands  Calcium transients  Bond strength  Mechanotransduction  Shear stress