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Knowledge Management System of Institue of Mechanics, CAS
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微重力重点实验室 [37]
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李宁 [37]
龙勉 [36]
吕守芹 [31]
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Direct mechanical exposure initiates hepatocyte proliferation
期刊论文
JHEP REPORTS, 2023, 卷号: 5, 期号: 12, 页码: 13
Authors:
Li, Wang
;
Wu Y(武亿)
;
Hu, Wenhui
;
Zhou J(周瑾)
;
Shu XY(舒芯钰)
;
Zhang XY(张晓宇)
;
Zhang, Ziliang
;
Wu, Huan
;
Du, Yu
;
Lv DY(吕东媛)
;
Lv SQ(吕守芹)
;
Li N(李宁)
;
Long M(龙勉)
Favorite
  |  
View/Download:44/0
  |  
Submit date:2024/01/02
Mechanotransduction
FAK
hepatic sinusoid chip
Potential Roles of YAP/TAZ Mechanotransduction in Spaceflight-Induced Liver Dysfunction
期刊论文
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES, 2023, 卷号: 24, 期号: 3, 页码: 20
Authors:
Li W(李旺)
;
Shu XY(舒芯钰)
;
Zhang XY(张晓宇)
;
Zhang ZL(张子良)
;
Sun SJ(孙树津)
;
Li N(李宁)
;
Long M(龙勉)
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View/Download:113/0
  |  
Submit date:2023/03/20
microgravity
liver metabolism
mechanosensing
cytoskeleton
nuclear deformation
phase separation
Characterizing liver sinusoidal endothelial cell fenestrae on soft substrates upon AFM imaging and deep learning
期刊论文
BIOCHIMICA ET BIOPHYSICA ACTA-GENERAL SUBJECTS, 2020, 卷号: 1864, 期号: 12, 页码: 9
Authors:
Li PW(李佩文)
;
Zhou J(周瑾)
;
Li W(李旺)
;
Wu H(吴欢)
;
Hu JR(胡锦荣)
;
Ding QH(丁奇寒)
;
Lv SQ(吕守芹)
;
Pan J
;
Zhang CY
;
Li N(李宁)
;
Long M(龙勉)
Adobe PDF(4976Kb)
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View/Download:631/366
  |  
Submit date:2020/11/30
Liver sinusoidal endothelial cells
Fenestrae
Atomic force microscopy
Imaging recognition
Fully convolutional networks
Substrate stiffness
Mechanical strength determines Ca2+ transients triggered by the engagement of beta(2) integrins to their ligands
期刊论文
EXPERIMENTAL CELL RESEARCH, 2020, 卷号: 387, 期号: 2, 页码: 7
Authors:
Shu XY(舒芯钰)
;
Li N(李宁)
;
Huang DD(黄丹丹)
;
Zhang Y(章燕)
;
Lv SQ(吕守芹)
;
Long M(龙勉)
View
  |  
Adobe PDF(1108Kb)
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View/Download:423/157
  |  
Submit date:2020/04/07
beta(2) integrin
Ligands
Calcium transients
Bond strength
Mechanotransduction
Shear stress
Microgravity-induced hepatogenic differentiation of rBMSCs on board the SJ-10 satellite
期刊论文
FASEB JOURNAL, 2019, 卷号: 33, 期号: 3, 页码: 4273-4286
Authors:
Lv DY(吕东媛)
;
Sun SJ(孙树津)
;
Zhang F(张帆)
;
Luo CH(罗春花)
;
Zheng L
;
Wu Y(武毅)
;
Li N(李宁)
;
Zhang C
;
Wang CZ
;
Chen Q
;
Long M(龙勉)
View
  |  
Adobe PDF(3477Kb)
  |  
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View/Download:291/93
  |  
Submit date:2019/04/11
mesenchymal stem cells
mechanotransduction
hepatocyte
signaling pathway
Binding of intercellular adhesion molecule 1 to beta(2)-integrin regulates distinct cell adhesion processes on hepatic and cerebral endothelium
期刊论文
AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY, 2018, 卷号: 315, 期号: 3, 页码: C409-C421
Authors:
Tong CF(佟春芳)
;
Zhang Y(章燕)
;
Lv SQ(吕守芹)
;
Li N(李宁)
;
Gong YX(龚一心)
;
Yang H
;
Feng SL
;
Du Y
;
Huang DD
;
Long M(龙勉)
View
  |  
Adobe PDF(1593Kb)
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View/Download:537/265
  |  
Submit date:2018/10/30
brain
ICAM-1
integrin
kinetics
liver
整合素LFA-1/Mac-1与不同配体相互作用的反应动力学及力谱差异
会议论文
第十二届全国生物力学学术会议暨第十四届全国生物流变学学术会议会议, 中国陕西西安, 2018年8月17日至21日
Authors:
李宁
;
杨浩
;
毛德斌
;
王曼柳
;
吕守芹
;
章燕
;
龙勉
View
  |  
Adobe PDF(163Kb)
  |  
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View/Download:225/36
  |  
Submit date:2019/11/21
Mac
LFA-1/Mac-1
反应动力学
PMN
整合素
Mechanical Strength and Structural Basis of beta(2) Integrin to Mediate Neutrophil Accumulation on Liver Sinusoidal Endothelial Cells: A Study Using Atomic Force Microscopy and Molecular Dynamics Simulations
期刊论文
CMES-COMPUTER MODELING IN ENGINEERING & SCIENCES, 2018, 卷号: 116, 期号: 2, 页码: 263-279
Authors:
Li N(李宁)
;
Zhang X(张潇)
;
Li PW
;
Yang H
;
Tong CF
;
Lv SQ(吕守芹)
;
Zhang Y(章燕)
;
Ye ZY
;
Pan J
;
Long M(龙勉)
View
  |  
Adobe PDF(865Kb)
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View/Download:375/184
  |  
Submit date:2018/10/30
Liver sinusoidal endothelial cells
neutrophils
beta(2) integrin
shear flow
mechanical strength
Microgravity-Induced Alterations of Inflammation-Related Mechanotransduction in Endothelial Cells on Board SJ-10 Satellite
期刊论文
FRONTIERS IN PHYSIOLOGY, 2018, 卷号: 9, 页码: 1025
Authors:
Li N(李宁)
;
Wang CZ(王成之)
;
Sun SJ(孙树津)
;
Zhang C(张晨)
;
Lv DY(吕东媛)
;
Chen Q(陈琴)
;
Long M(龙勉)
View
  |  
Adobe PDF(3456Kb)
  |  
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View/Download:598/411
  |  
Submit date:2018/10/19
Microgravity
Sj-10 Satellite
Endothelial Cells
Adhesive Molecules
Cytoskeleton
Mechanotransduction
Nitric Oxide
Exosome Rna
Ligand-specific binding forces of LFA-1 and Mac-1 in neutrophil adhesion and crawling
期刊论文
MOLECULAR BIOLOGY OF THE CELL, 2018, 卷号: 29, 期号: 4, 页码: 408-418
Authors:
Li N(李宁)
;
Yang H(杨浩)
;
Wang ML
;
Lv SQ(吕守芹)
;
Zhang Y(章燕)
;
Long M(龙勉)
View
  |  
Adobe PDF(1832Kb)
  |  
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  |  
View/Download:384/85
  |  
Submit date:2018/10/30