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FAK-p38 signaling serves as a potential target for reverting matrix stiffness-modulated liver sinusoidal endothelial cell defenestration 期刊论文
BIOMATERIALS, 2024, 卷号: 305, 页码: 17
作者:  Zhang XY(张晓宇);  Li PW(李培文);  Zhou J(周瑾);  Zhang ZL(张子良);  Wu H(吴欢);  Shu XY(舒芯钰);  Li W(李旺);  Wu Y(武亿);  Du Y(杜宇);  Lv DY(吕东媛);  Lv SQ(吕守芹);  Li N(李宁);  Long M(龙勉)
收藏  |  浏览/下载：3/0  |  提交时间：2024/04/02
Liver sinusoidal endothelial cells  Fenestrae  Liver fibrosis  Cytoskeleton remodeling  FAK  MAPK  
Human vascularized bile duct-on-a chip: a multi-cellular micro-physiological system for studying cholestatic liver disease 期刊论文
BIOFABRICATION, 2024, 卷号: 16, 期号: 1, 页码: 13
作者:  Du, Yu;  de Jong, Iris E. M.;  Gupta, Kapish;  Waisbourd-Zinman, Orit;  Har-Zahav, Adi;  Soroka, Carol J.;  Boyer, James L.;  Llewellyn, Jessica;  Liu, Chengyang;  Naji, Ali;  Polacheck, William J.;  Wells, Rebecca G.
收藏  |  浏览/下载：295/0  |  提交时间：2023/11/28
microfluidic device  cholangiopathy  tissue engineering  organ-on-a-chip  primary sclerosing cholangitis  
Direct mechanical exposure initiates hepatocyte proliferation 期刊论文
JHEP REPORTS, 2023, 卷号: 5, 期号: 12, 页码: 13
作者:  Li, Wang;  Wu Y(武亿);  Hu, Wenhui;  Zhou J(周瑾);  Shu XY(舒芯钰);  Zhang XY(张晓宇);  Zhang, Ziliang;  Wu, Huan;  Du, Yu;  Lv DY(吕东媛);  Lv SQ(吕守芹);  Li N(李宁);  Long M(龙勉)
Adobe PDF(3334Kb)  |  收藏  |  浏览/下载：49/0  |  提交时间：2024/01/02
Mechanotransduction  FAK  hepatic sinusoid chip  
A fetal wound healing program after intrauterine bile duct injury may contribute to biliary atresia 期刊论文
JOURNAL OF HEPATOLOGY, 2023, 卷号: 79, 期号: 6, 页码: 13
作者:  de Jong, Iris EM;  Hunt, Mallory L;  Chen, Dongning;  Du Y(杜宇);  Llewellyn, Jessica;  Gupta, Kapish;  Li, David;  Erxleben, Dorothea;  Rivas, Felipe;  Hall, Adam R;  Furth, Emma E;  Naji, Ali;  Liu, Chengyang;  Dhand, Abhishek;  Burdick, Jason A;  Davey, Marcus G;  Flake, Alan W;  Porte, Robert J;  Russo, Pierre A;  Gaynor, J William;  Wells, Rebecca G
Adobe PDF(6669Kb)  |  收藏  |  浏览/下载：47/0  |  提交时间：2024/01/22
biliary atresia  hyaluronic acid  peribiliary glands  cholangiocyte  cholangiopathy  
Matrix stiffness and shear stresses modulate hepatocyte functions in a fibrotic liver sinusoidal model 期刊论文
AMERICAN JOURNAL OF PHYSIOLOGY-GASTROINTESTINAL AND LIVER PHYSIOLOGY, 2020, 卷号: 320, 期号: 3, 页码: G272-G282
作者:  Li W(李旺);  Li PW(李培文);  Li N(李宁);  Du Y(杜宇);  Lv SQ(吕守芹);  Elad, David;  Long M(龙勉)
Adobe PDF(2812Kb)  |  收藏  |  浏览/下载：170/82  |  提交时间：2022/10/25
hepatocytes  liver fibrosis  matrix stiffness  shear flow  three-dimensional liver sinusoidal model  
Binding of intercellular adhesion molecule 1 to beta(2)-integrin regulates distinct cell adhesion processes on hepatic and cerebral endothelium 期刊论文
AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY, 2018, 卷号: 315, 期号: 3, 页码: C409-C421
作者:  Tong CF(佟春芳);  Zhang Y(章燕);  Lv SQ(吕守芹);  Li N(李宁);  Gong YX(龚一心);  Yang H;  Feng SL;  Du Y;  Huang DD;  Long M(龙勉)
浏览  |  Adobe PDF(1593Kb)  |  收藏  |  浏览/下载：542/266  |  提交时间：2018/10/30
brain  ICAM-1  integrin  kinetics  liver  
组织硬度对肝血窦内皮细胞筛孔演化的调控及其力学信号转导机制 会议论文
第十二届全国生物力学学术会议暨第十四届全国生物流变学学术会议会议, 中国陕西西安, 2018年8月17日至21日
作者:  李珮文;  李宁;  杜宇;  龙勉
浏览  |  Adobe PDF(158Kb)  |  收藏  |  浏览/下载：191/60  |  提交时间：2019/11/21
肝血窦内皮细胞  毛细血管  基底硬度  
Liver sinusoid on a chip 期刊论文
MICROFLUIDICS IN CELL BIOLOGY, PT A: MICROFLUIDICS FOR MULTICELLULAR SYSTEMS, 2018, 卷号: 146, 页码: 105-134
作者:  Du Y(杜宇);  Li N(李宁);  Long M(龙勉)
浏览  |  Adobe PDF(3794Kb)  |  收藏  |  浏览/下载：518/271  |  提交时间：2019/05/30
Neutrophil adhesion and crawling dynamics on liver sinusoidal endothelial cells under shear flow 期刊论文
EXPERIMENTAL CELL RESEARCH, 2017, 卷号: 351, 期号: 1, 页码: 91-99
作者:  Yang H(杨浩);  Li N(李宁);  Du Y(杜宇);  Tong CF(佟春芳);  Lv SQ(吕守芹);  Hu JR;  Zhang Y(章燕);  Long M(龙勉);  Long, M (reprint author), Chinese Acad Sci, Inst Mech, Beijing 100190, Peoples R China.
浏览  |  Adobe PDF(2025Kb)  |  收藏  |  浏览/下载：663/269  |  提交时间：2017/07/24
Neutrophils  Liver Sinusoids  Shear Flow  Adhesive Molecules  Kupffer Cells  
Mimicking liver sinusoidal structures and functions using a 3D-configured microfluidic chip 期刊论文
LAB ON A CHIP, 2017, 卷号: 17, 期号: 5, 页码: 782-794
作者:  Du Y(杜宇);  Li N(李宁);  Yang H(杨浩);  Luo CH(罗春花);  Gong YX;  Tong CF(佟春芳);  Gao YX(高宇新);  Lv SQ(吕守芹);  Long M(龙勉);  Long, M (reprint author), Chinese Acad Sci, Key Lab Micrograv, Natl Micrograv Lab, Ctr Biomech & Bioengn, Beijing 100190, Peoples R China.;  Long, M (reprint author), Chinese Acad Sci, Beijing Key Lab Engn Construct & Mech, Inst Mech, Beijing 100190, Peoples R China.;  Long, M (reprint author), Univ Chinese Acad Sci, Sch Engn Sci, Beijing 100049, Peoples R China.
浏览  |  Adobe PDF(6728Kb)  |  收藏  |  浏览/下载：751/487  |  提交时间：2017/07/24