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FAK-p38 signaling serves as a potential target for reverting matrix stiffness-modulated liver sinusoidal endothelial cell defenestration 期刊论文
BIOMATERIALS, 2024, 卷号: 305, 页码: 17
作者:  Zhang XY(张晓宇);  Li PW(李培文);  Zhou J(周瑾);  Zhang ZL(张子良);  Wu H(吴欢);  Shu XY(舒芯钰);  Li W(李旺);  Wu Y(武亿);  Du Y(杜宇);  Lv DY(吕东媛);  Lv SQ(吕守芹);  Li N(李宁);  Long M(龙勉)
收藏  |  浏览/下载:3/0  |  提交时间:2024/04/02
Liver sinusoidal endothelial cells  Fenestrae  Liver fibrosis  Cytoskeleton remodeling  FAK  MAPK  
Direct mechanical exposure initiates hepatocyte proliferation 期刊论文
JHEP REPORTS, 2023, 卷号: 5, 期号: 12, 页码: 13
作者:  Li, Wang;  Wu Y(武亿);  Hu, Wenhui;  Zhou J(周瑾);  Shu XY(舒芯钰);  Zhang XY(张晓宇);  Zhang, Ziliang;  Wu, Huan;  Du, Yu;  Lv DY(吕东媛);  Lv SQ(吕守芹);  Li N(李宁);  Long M(龙勉)
Adobe PDF(3334Kb)  |  收藏  |  浏览/下载:49/0  |  提交时间:2024/01/02
Mechanotransduction  FAK  hepatic sinusoid chip  
DNA methyltransferase 1 deficiency improves macrophage motility and wound healing by ameliorating cholesterol accumulation 期刊论文
NPJ REGENERATIVE MEDICINE, 2023, 卷号: 8, 期号: 1, 页码: 29
作者:  Zhao, Chuanrong;  Yang, Qianru;  Tang, Runze;  Li, Wang;  Wang, Jin;  Yang, Fangfang;  Zhao, Jianan;  Zhu, Juanjuan;  Pang, Wei;  Li N(李宁);  Zhang, Xu;  Tian, Xiao Yu;  Yao, Weijuan;  Zhou, Jing
Adobe PDF(4818Kb)  |  收藏  |  浏览/下载:31/0  |  提交时间:2023/07/17
Biomechanics in liver regeneration after partial hepatectomy 期刊论文
FRONTIERS IN BIOENGINEERING AND BIOTECHNOLOGY, 2023, 卷号: 11, 页码: 1165651
作者:  Wu Y(武亿);  Li N(李宁);  Shu XY(舒芯钰);  Li W(李旺);  Zhang XY(张晓宇);  Lv DY(吕东媛);  Long M(龙勉)
Adobe PDF(2065Kb)  |  收藏  |  浏览/下载:60/0  |  提交时间:2023/07/17
liver regeneration  partial hepatectomy  hemodynamics  mechanical loading  mechanotransduction  
Numerical Investigation on the Ventilated Supercavity around a Body under Free Surface Effect 期刊论文
JOURNAL OF MARINE SCIENCE AND ENGINEERING, 2023, 卷号: 11, 期号: 5, 页码: 912
作者:  Zhi, Yuchang;  Zhan, Jiemin;  Huang RF(黄仁芳);  Wang YW(王一伟);  Li, Ning
Adobe PDF(14975Kb)  |  收藏  |  浏览/下载:48/1  |  提交时间:2023/06/15
ventilated supercavity  free surface  dynamic behavior  gas leakage  
Potential Roles of YAP/TAZ Mechanotransduction in Spaceflight-Induced Liver Dysfunction 期刊论文
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES, 2023, 卷号: 24, 期号: 3, 页码: 20
作者:  Li W(李旺);  Shu XY(舒芯钰);  Zhang XY(张晓宇);  Zhang ZL(张子良);  Sun SJ(孙树津);  Li N(李宁);  Long M(龙勉)
Adobe PDF(1498Kb)  |  收藏  |  浏览/下载:114/0  |  提交时间:2023/03/20
microgravity  liver metabolism  mechanosensing  cytoskeleton  nuclear deformation  phase separation  
Disturbed Flow-Facilitated Margination and Targeting of Nanodisks Protect against Atherosclerosis 期刊论文
SMALL, 2023, 卷号: 19, 期号: 2, 页码: 10.1002/smll.202204694
作者:  Zhao, ChuanRong;  Li, Jingyi;  Jiang, ZhiTong;  Zhu, JuanJuan;  Zhao, JiaNan;  Yang, QianRu;  Yao, Weijuan;  Pang, Wei;  Li N(李宁);  Yu, Miaorong;  Gan, Yong;  Zhou, Jing
Adobe PDF(4465Kb)  |  收藏  |  浏览/下载:185/67  |  提交时间:2022/12/20
atherosclerosis  decitabine  endothelial inflammation  hemodynamics  nanoparticles  
Matrix stiffness exacerbates the proinflammatory responses of vascular smooth muscle cell through the DDR1-DNMT1 mechanotransduction axis 期刊论文
BIOACTIVE MATERIALS, 2022, 卷号: 17, 页码: 406-424
作者:  Wang, Jin;  Xie, Si-an;  Li N(李宁);  Zhang, Tao;  Yao, Weijuan;  Zhao, Hucheng;  Pang, Wei;  Han, Lili;  Liu, Jiayu;  Zhou, Jing
Adobe PDF(21819Kb)  |  收藏  |  浏览/下载:269/23  |  提交时间:2022/06/10
Matrix stiffness  Inflammation  DDR1  DNMT1  Mechanotransduction  
Multiscale biomechanics and mechanotransduction from liver fibrosis to cancer 期刊论文
ADVANCED DRUG DELIVERY REVIEWS, 2022, 卷号: 188, 页码: 114448
作者:  Li N(李宁);  Zhang XY(张晓宇);  Zhou J(周瑾);  Li W(李旺);  Shu XY(舒芯钰);  Wu Y(武亿);  Long M(龙勉)
Adobe PDF(2553Kb)  |  收藏  |  浏览/下载:313/86  |  提交时间:2022/10/23
Liver tissue stiffness  Shear stress  Hydrostatic pressure  Hepatocytes  Hepatocellular carcinoma  Liver sinusoidal endothelial cells  Hepatic stellate cells  Mechanotransduction pathways  Mechanomedicine  Drug design and delivery  
细胞力学2021年度研究进展 期刊论文
医用生物力学, 2022, 卷号: 37, 期号: 04, 页码: 584-590
作者:  李宁;  龙勉
Adobe PDF(490Kb)  |  收藏  |  浏览/下载:215/69  |  提交时间:2022/10/17
细胞力学  力学-生物学耦合  力学微环境