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Gravity-Vector Induces Mechanical Remodeling of rMSCs via Combined Substrate Stiffness and Orientation 期刊论文
FRONTIERS IN BIOENGINEERING AND BIOTECHNOLOGY, 2022, 卷号: 9, 页码: 14
Authors:  Zhang C(张晨);  Lv DY(吕东媛);  Zhang F(张帆);  Wu Y(武亿);  Zheng L(郑鲁);  Zhang XY(张晓宇);  Li Z(李展);  Sun SJ(孙树津);  龙勉Mian
Favorite  |  View/Download:44/0  |  Submit date:2022/05/17
substrate stiffness  orientation  mechanosensing  nucleus translocation  cytoskeletal remodeling  focal adhesion complex reorganization  cellular morphology  
基底硬度调控胚胎干细胞内胚层向分化的机理研究 期刊论文
医用生物力学, 2021, 卷号: 36, 期号: S1, 页码: 493
Authors:  郑璐;  张帆;  武亿;  吕东媛;  龙勉
Adobe PDF(2379Kb)  |  Favorite  |  View/Download:14/2  |  Submit date:2022/03/16
基底硬度  胚胎干细胞  黏着斑蛋白  内胚层  
拉伸诱导的肝血窦内皮细胞分泌对肝细胞功能和增殖的影响 期刊论文
医用生物力学, 2021, 卷号: 36, 期号: S1, 页码: 305
Authors:  武亿;  吕东媛;  龙勉
Adobe PDF(2268Kb)  |  Favorite  |  View/Download:23/3  |  Submit date:2022/03/16
肝细胞功能  肝血窦内皮细胞  肝再生  
胚胎干细胞肝向分化过程对基底力学微环境的响应规律及机制 期刊论文
医用生物力学, 2021, 卷号: 36, 期号: S1, 页码: 156
Authors:  吕东媛;  罗春花;  郑璐;  张帆;  武亿;  龙勉
Adobe PDF(1929Kb)  |  Favorite  |  View/Download:15/2  |  Submit date:2022/03/16
胚胎干细胞  响应规律  微环境  
Hepatic differentiation of human embryonic stem cells by coupling substrate stiffness and microtopography 期刊论文
BIOMATERIALS SCIENCE, 2021, 页码: 15
Authors:  Luo CH(罗春花);  Lv DY(吕东媛);  Zheng L(郑鲁);  Zhang F(张帆);  Zhang X(张潇);  Lv SQ(吕守芹);  Zhang C(张晨);  Jia Xiaohua;  Shu XY(舒芯钰);  Li PW(李培文);  Li Z(李展);  Long M(龙勉)
Adobe PDF(7505Kb)  |  Favorite  |  View/Download:140/52  |  Submit date:2021/05/17
Mechanotransduction of liver sinusoidal endothelial cells under varied mechanical stimuli 期刊论文
ACTA MECHANICA SINICA, 2021, 页码: 17
Authors:  Shu XY(舒芯钰);  Li N(李宁);  Wu Y(武亿);  Li W(李旺);  Zhang XY(张晓宇);  Li PW(李培文);  Lv DY(吕东媛);  Lv SQ(吕守芹);  Long M(龙勉)
Adobe PDF(1359Kb)  |  Favorite  |  View/Download:161/22  |  Submit date:2021/05/06
Liver sinusoidal endothelial cell  Shear stress  Mechanical stretch  Extracellular matrix  Stiffness  
基质力学微环境调控人胚胎干细胞肝向分化 会议论文
2020生物医学材料与技术交叉青年论坛, 宁波, 2020.12.26-28
Authors:  吕东媛;  龙勉.
Favorite  |  View/Download:49/0  |  Submit date:2021/02/01
基底硬度耦合拓扑结构影响人胚胎干细胞的肝向分化. 会议论文
第四届全国生物力学青年学者学术研讨会, 杭州, 2020.11.20-22
Authors:  吕东媛
Favorite  |  View/Download:27/0  |  Submit date:2021/02/01
流体剪切促进人胚胎干细胞的启动. 会议论文
2020北京生物力学博士论坛, 北京, 2020. 11. 7
Authors:  武亿;  吕东媛;  王家文;  张帆;  龙勉.
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Regulation of hepatic differentiation of human embryonic stem cells by calcium silicate extracts for liver injury repairing 期刊论文
Applied Materials Today, 2020, 卷号: 20, 页码: 100730
Authors:  Zheng L;  Lv DY(吕东媛);  Zhang F;  Xing M;  Wang XY;  Jia XH;  Shu XY;  Li PW(李培文);  Lv SQ(吕守芹);  Chang J;  Long M(龙勉)
Adobe PDF(3951Kb)  |  Favorite  |  View/Download:42/13  |  Submit date:2021/01/29
Human embryonic stem cells  Hepatic differentiation  Hepatocyte-like cells  Calcium silicate extracts  Liver injury repair