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Knowledge Management System of Institue of Mechanics, CAS
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Human vascularized bile duct-on-a chip: a multi-cellular micro-physiological system for studying cholestatic liver disease
期刊论文
BIOFABRICATION, 2024, 卷号: 16, 期号: 1, 页码: 13
Authors:
Du, Yu
;
de Jong, Iris E. M.
;
Gupta, Kapish
;
Waisbourd-Zinman, Orit
;
Har-Zahav, Adi
;
Soroka, Carol J.
;
Boyer, James L.
;
Llewellyn, Jessica
;
Liu, Chengyang
;
Naji, Ali
;
Polacheck, William J.
;
Wells, Rebecca G.
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Submit date:2023/11/28
microfluidic device
cholangiopathy
tissue engineering
organ-on-a-chip
primary sclerosing cholangitis
Direct mechanical exposure initiates hepatocyte proliferation
期刊论文
JHEP REPORTS, 2023, 卷号: 5, 期号: 12, 页码: 13
Authors:
Li, Wang
;
Wu Y(武亿)
;
Hu, Wenhui
;
Zhou J(周瑾)
;
Shu XY(舒芯钰)
;
Zhang XY(张晓宇)
;
Zhang, Ziliang
;
Wu, Huan
;
Du, Yu
;
Lv DY(吕东媛)
;
Lv SQ(吕守芹)
;
Li N(李宁)
;
Long M(龙勉)
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Submit date:2024/01/02
Mechanotransduction
FAK
hepatic sinusoid chip
A fetal wound healing program after intrauterine bile duct injury may contribute to biliary atresia
期刊论文
JOURNAL OF HEPATOLOGY, 2023, 卷号: 79, 期号: 6, 页码: 13
Authors:
de Jong, Iris EM
;
Hunt, Mallory L
;
Chen, Dongning
;
Du Y(杜宇)
;
Llewellyn, Jessica
;
Gupta, Kapish
;
Li, David
;
Erxleben, Dorothea
;
Rivas, Felipe
;
Hall, Adam R
;
Furth, Emma E
;
Naji, Ali
;
Liu, Chengyang
;
Dhand, Abhishek
;
Burdick, Jason A
;
Davey, Marcus G
;
Flake, Alan W
;
Porte, Robert J
;
Russo, Pierre A
;
Gaynor, J William
;
Wells, Rebecca G
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View/Download:39/0
  |  
Submit date:2024/01/22
biliary atresia
hyaluronic acid
peribiliary glands
cholangiocyte
cholangiopathy
Matrix stiffness and shear stresses modulate hepatocyte functions in a fibrotic liver sinusoidal model
期刊论文
AMERICAN JOURNAL OF PHYSIOLOGY-GASTROINTESTINAL AND LIVER PHYSIOLOGY, 2020, 卷号: 320, 期号: 3, 页码: G272-G282
Authors:
Li W(李旺)
;
Li PW(李培文)
;
Li N(李宁)
;
Du Y(杜宇)
;
Lv SQ(吕守芹)
;
Elad, David
;
Long M(龙勉)
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Submit date:2022/10/25
hepatocytes
liver fibrosis
matrix stiffness
shear flow
three-dimensional liver sinusoidal model
Binding of intercellular adhesion molecule 1 to beta(2)-integrin regulates distinct cell adhesion processes on hepatic and cerebral endothelium
期刊论文
AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY, 2018, 卷号: 315, 期号: 3, 页码: C409-C421
Authors:
Tong CF(佟春芳)
;
Zhang Y(章燕)
;
Lv SQ(吕守芹)
;
Li N(李宁)
;
Gong YX(龚一心)
;
Yang H
;
Feng SL
;
Du Y
;
Huang DD
;
Long M(龙勉)
View
  |  
Adobe PDF(1593Kb)
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View/Download:531/262
  |  
Submit date:2018/10/30
brain
ICAM-1
integrin
kinetics
liver
组织硬度对肝血窦内皮细胞筛孔演化的调控及其力学信号转导机制
会议论文
第十二届全国生物力学学术会议暨第十四届全国生物流变学学术会议会议, 中国陕西西安, 2018年8月17日至21日
Authors:
李珮文
;
李宁
;
杜宇
;
龙勉
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Submit date:2019/11/21
肝血窦内皮细胞
毛细血管
基底硬度
Liver sinusoid on a chip
期刊论文
MICROFLUIDICS IN CELL BIOLOGY, PT A: MICROFLUIDICS FOR MULTICELLULAR SYSTEMS, 2018, 卷号: 146, 页码: 105-134
Authors:
Du Y(杜宇)
;
Li N(李宁)
;
Long M(龙勉)
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  |  
Adobe PDF(3794Kb)
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View/Download:505/266
  |  
Submit date:2019/05/30
Neutrophil adhesion and crawling dynamics on liver sinusoidal endothelial cells under shear flow
期刊论文
EXPERIMENTAL CELL RESEARCH, 2017, 卷号: 351, 期号: 1, 页码: 91-99
Authors:
Yang H(杨浩)
;
Li N(李宁)
;
Du Y(杜宇)
;
Tong CF(佟春芳)
;
Lv SQ(吕守芹)
;
Hu JR
;
Zhang Y(章燕)
;
Long M(龙勉)
;
Long, M (reprint author), Chinese Acad Sci, Inst Mech, Beijing 100190, Peoples R China.
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  |  
Submit date:2017/07/24
Neutrophils
Liver Sinusoids
Shear Flow
Adhesive Molecules
Kupffer Cells
Mimicking liver sinusoidal structures and functions using a 3D-configured microfluidic chip
期刊论文
LAB ON A CHIP, 2017, 卷号: 17, 期号: 5, 页码: 782-794
Authors:
Du Y(杜宇)
;
Li N(李宁)
;
Yang H(杨浩)
;
Luo CH(罗春花)
;
Gong YX
;
Tong CF(佟春芳)
;
Gao YX(高宇新)
;
Lv SQ(吕守芹)
;
Long M(龙勉)
;
Long, M (reprint author), Chinese Acad Sci, Key Lab Micrograv, Natl Micrograv Lab, Ctr Biomech & Bioengn, Beijing 100190, Peoples R China.
;
Long, M (reprint author), Chinese Acad Sci, Beijing Key Lab Engn Construct & Mech, Inst Mech, Beijing 100190, Peoples R China.
;
Long, M (reprint author), Univ Chinese Acad Sci, Sch Engn Sci, Beijing 100049, Peoples R China.
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Submit date:2017/07/24
肝血窦体外三维模型组织构建及其细胞聚集/粘附动力学研究
学位论文
博士论文,北京: 中国科学院大学, 2016
Authors:
杜宇
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Submit date:2016/08/29