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FAK-p38 signaling serves as a potential target for reverting matrix stiffness-modulated liver sinusoidal endothelial cell defenestration 期刊论文
BIOMATERIALS, 2024, 卷号: 305, 页码: 17
作者:  Zhang XY(张晓宇);  Li PW(李培文);  Zhou J(周瑾);  Zhang ZL(张子良);  Wu H(吴欢);  Shu XY(舒芯钰);  Li W(李旺);  Wu Y(武亿);  Du Y(杜宇);  Lv DY(吕东媛);  Lv SQ(吕守芹);  Li N(李宁);  Long M(龙勉)
收藏  |  浏览/下载：7/0  |  提交时间：2024/04/02
Liver sinusoidal endothelial cells  Fenestrae  Liver fibrosis  Cytoskeleton remodeling  FAK  MAPK  
Multiscale biomechanics and mechanotransduction from liver fibrosis to cancer 期刊论文
ADVANCED DRUG DELIVERY REVIEWS, 2022, 卷号: 188, 页码: 114448
作者:  Li N(李宁);  Zhang XY(张晓宇);  Zhou J(周瑾);  Li W(李旺);  Shu XY(舒芯钰);  Wu Y(武亿);  Long M(龙勉)
Adobe PDF(2553Kb)  |  收藏  |  浏览/下载：319/88  |  提交时间：2022/10/23
Liver tissue stiffness  Shear stress  Hydrostatic pressure  Hepatocytes  Hepatocellular carcinoma  Liver sinusoidal endothelial cells  Hepatic stellate cells  Mechanotransduction pathways  Mechanomedicine  Drug design and delivery  
Characterizing liver sinusoidal endothelial cell fenestrae on soft substrates upon AFM imaging and deep learning 期刊论文
BIOCHIMICA ET BIOPHYSICA ACTA-GENERAL SUBJECTS, 2020, 卷号: 1864, 期号: 12, 页码: 9
作者:  Li PW(李培文);  Zhou J(周瑾);  Li W(李旺);  Wu H(吴欢);  Hu JR(胡锦荣);  Ding QH(丁奇寒);  Lv SQ(吕守芹);  Pan J;  Zhang CY;  Li N(李宁);  Long M(龙勉)
Adobe PDF(4976Kb)  |  收藏  |  浏览/下载：644/373  |  提交时间：2020/11/30
Liver sinusoidal endothelial cells  Fenestrae  Atomic force microscopy  Imaging recognition  Fully convolutional networks  Substrate stiffness  
Mechanical Strength and Structural Basis of beta(2) Integrin to Mediate Neutrophil Accumulation on Liver Sinusoidal Endothelial Cells: A Study Using Atomic Force Microscopy and Molecular Dynamics Simulations 期刊论文
CMES-COMPUTER MODELING IN ENGINEERING & SCIENCES, 2018, 卷号: 116, 期号: 2, 页码: 263-279
作者:  Li N(李宁);  Zhang X(张潇);  Li PW;  Yang H;  Tong CF;  Lv SQ(吕守芹);  Zhang Y(章燕);  Ye ZY;  Pan J;  Long M(龙勉)
Adobe PDF(865Kb)  |  收藏  |  浏览/下载：386/188  |  提交时间：2018/10/30
Liver sinusoidal endothelial cells  neutrophils  beta(2) integrin  shear flow  mechanical strength  
Microgravity-Induced Alterations of Inflammation-Related Mechanotransduction in Endothelial Cells on Board SJ-10 Satellite 期刊论文
FRONTIERS IN PHYSIOLOGY, 2018, 卷号: 9, 页码: 1025
作者:  Li N(李宁);  Wang CZ(王成之);  Sun SJ(孙树津);  Zhang C(张晨);  Lv DY(吕东媛);  Chen Q(陈琴);  Long M(龙勉)
Adobe PDF(3456Kb)  |  收藏  |  浏览/下载：602/412  |  提交时间：2018/10/19
Microgravity  Sj-10 Satellite  Endothelial Cells  Adhesive Molecules  Cytoskeleton  Mechanotransduction  Nitric Oxide  Exosome Rna  
Spreading of human neutrophils on an ICAM-1-immobilized substrate under shear flow 期刊论文
CHINESE SCIENCE BULLETIN, 2012, 卷号: 57, 期号: 7, 页码: 769-775
作者:  Zhan DY(展冬颖);  Zhang Y(章燕);  Long M(龙勉);  Long, MA;  Chinese Acad Sci, Inst Mech, Key Lab Micrograv, Natl Micrograv Lab, Beijing 100190, Peoples R China.
Adobe PDF(685Kb)  |  收藏  |  浏览/下载：967/227  |  提交时间：2013/01/18
Neutrophil  Spreading  Beta 2 Integrin  Icam-1  Shear Stress  Cell-surface Adhesion  L-selectin  Polymorphonuclear Leukocytes  Endothelial-cells  Rolling Adhesions  P-selectin  Integrin  Affinity  Stress  Icam-1  
Molecular dynamics simulation of shear- and stretch-induced dissociation of P-selectin/PSGL-1 complex 期刊论文
BIOPHYSICAL JOURNAL, 2012, 卷号: 102, 期号: 1, 页码: 112-120
作者:  Kang YY(康英永);  Lv SQ(吕守芹);  Ren P(任鹏);  Huo B(霍波);  Long M(龙勉);  Huo, B (reprint author), Chinese Acad Sci, Inst Mech, Key Lab Micrograv, Natl Micrograv Lab, Beijing 100080, Peoples R China.
Adobe PDF(1143Kb)  |  收藏  |  浏览/下载：959/196  |  提交时间：2013/01/18
Selectin Glycoprotein Ligand-1  Granule Membrane-protein  P-selectin  Cell-adhesion  Beta-switch  Endothelial-cells  Catch Bonds  Ib-alpha  Flow  Transition  
Fluid Dynamics Analysis of a Novel Micropatterned Cell Bioreactor 期刊论文
Annals of Biomedical Engineering, 2011, 卷号: 39, 期号: 5, 页码: 1592-1605
作者:  Cui YH;  Huo B(霍波);  Sun SJ(孙树津);  Yang F(杨帆);  Gao YX(高宇欣);  Pan J;  Long M(龙勉);  Long, MA (reprint author), Chinese Acad Sci, Inst Mech, Key Lab Micrograv, Beijing 100190, Peoples R China
Adobe PDF(1354Kb)  |  收藏  |  浏览/下载：989/189  |  提交时间：2012/04/01
Fluid Dynamics  Cell Bioreactor  Micropattern  Steady Shear-stress  Endothelial-cells  Flow  Mechanotransduction  Environment  Prediction  Scaffolds  Adhesion  Chamber  Systems  
Quasi-3D Cytoskeletal Dynamics of Osteocytes under Fluid Flow 期刊论文
Biophysical Journal, 2010, 卷号: 99, 期号: 9, 页码: 2812-2820
作者:  Baik AD;  Lu XL;  Qiu J;  Huo B(霍波);  Hillman EMC;  Dong C;  Guo XE;  Huo B
Adobe PDF(1028Kb)  |  收藏  |  浏览/下载：1192/190  |  提交时间：2011/03/01
Living Endothelial-cells  Viscoelastic Properties  Articular-cartilage  Shear-stress  Bone-cells  In-vitro  Adhesion  Deformation  Prestress  Strain