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Two dimensional measurements of receptor ligand interactions 期刊论文
FRONTIERS IN MOLECULAR BIOSCIENCES, 2023, 卷号: 10, 页码: 1154074
作者:  Zheng SJ(郑松杰);  Zou M(邹敏);  Shao YF(邵颖峰);  Wu, Huaping;  Wu, Helong;  Wang XH(王小环)
Adobe PDF(1090Kb)  |  收藏  |  浏览/下载:110/0  |  提交时间:2023/04/20
receptor ligand interaction  binding kinetics  kinetic on rate  kinetic off rate  binding affinity  two dimensional measuring methods  
Insights into intercellular receptor-ligand binding kinetics in cell communication 期刊论文
FRONTIERS IN BIOENGINEERING AND BIOTECHNOLOGY, 2022, 卷号: 10, 页码: 953353
作者:  An, Chenyi;  Wang, Xiaohuan;  Song F(宋凡);  Hu, Jinglei;  Li L(李龙)
Adobe PDF(1265Kb)  |  收藏  |  浏览/下载:89/29  |  提交时间:2022/10/23
cell communication  intercellular receptor-ligand binding kinetics  protein-membrane interaction  biomechanical force  bioelectric microenvironment  
Mechanokinetics of receptor-ligand interactions in cell adhesion 期刊论文
Acta Mechanica Sinica, 2015, 卷号: 31, 期号: 2, 页码: 248-258
作者:  Li N(李宁);  Lv SQ(吕守芹);  Zhang Y(章燕);  Long M(龙勉);  Long, M (reprint author), Chinese Acad Sci, Ctr Biomech & Bioengn, Key Lab Micrograv, Natl Micrograv Lab, Beijing 100190, Peoples R China.
浏览  |  Adobe PDF(809Kb)  |  收藏  |  浏览/下载:523/159  |  提交时间:2015/07/21
Receptor-ligand Interactions  Selectins  Beta(2) Integrins  2d Binding Kinetics  
Spring constant regulate selectin-ligand bond dissociation 会议论文
第五届中美生物医学工程暨海内外生物力学学术研讨会, 中国北京/Beijing, China, 2013-08-01
作者:  Zhang Y(章燕);  Sun GY(孙淦云);  Lv SQ(吕守芹);  Long M(龙勉)
浏览  |  Adobe PDF(91Kb)  |  收藏  |  浏览/下载:470/116  |  提交时间:2014/04/02
Dissociation  Regulate  Selectin  Constant  Formation  Further  Increased  Stiffness  Lifetime  Ligand  Binding  Assay  Probe  Force  Kinetics  Mainly  Reverse  Values  Well  Found  
Tyrosine replacement of PSGL-1 reduces association kinetics with P- and L-selectin on the cell membrane 期刊论文
BIOPHYSICAL JOURNAL, 2012, 卷号: 103, 期号: 4, 页码: 777-785
作者:  Xiao BT(肖波涛);  Tong CF(佟春芳);  Jia XL(贾潇凌);  Guo R(郭瑞);  Lv SQ(吕守芹);  Zhang Y(章燕);  McEver RP;  Zhu C;  Long M(龙勉);  Long, MA;  Chinese Acad Sci, Inst Mech, Key Lab Micrograv, Beijing 100080, Peoples R China.
Adobe PDF(775Kb)  |  收藏  |  浏览/下载:1028/265  |  提交时间:2013/01/18
Ligand Binding-kinetics  Glycoprotein Ligand-1  Molecular-dynamics  Adhesion  Sulfation  Proteins  Glycosulfopeptides  Identification  Dissociation  Recognition  
Advances in Experiments and Modeling in Micro- and Nano-Biomechanics: A Mini Review 期刊论文
Cellular and Molecular Bioengineering, 2011, 卷号: 4, 期号: 3, 页码: 327-339
作者:  Long M(龙勉);  Sato M;  Lim CT;  Wu JH;  Adachi T;  Inoue Y;  Long, M (reprint author), Chinese Acad Sci, Key Lab Micrograv, Ctr Biomech & Bioengn, Inst Mech, Beijing 100190, Peoples R China
Adobe PDF(2481Kb)  |  收藏  |  浏览/下载:1605/337  |  提交时间:2012/04/01
Cellular Mechanics  Molecular Biomechanics  Experimental Techniques  Theoretical Modeling  Computations  Fluid Shear-stress  Endothelial-cell Proliferation  Adhesive Dynamics Simulation  Ligand Binding-kinetics  Glycoprotein-ib-alpha  Von-willebrand-factor  Molecular-dynamics  Mechanical-stress  Beta-switch  2-dimensional Kinetics  
Determining beta(2)-Integrin and Intercellular Adhesion Molecule 1 Binding Kinetics in Tumor Cell Adhesion to Leukocytes and Endothelial Cells by a Gas-driven Micropipette Assay 期刊论文
Journal of Biological Chemistry, 2011, 卷号: 286, 期号: 40, 页码: 34777-34787
作者:  Fu ZL(傅长亮);  Tong CF(佟春芳);  Wang ML;  Gao YX(高宇欣);  Zhang Y(章燕);  Lv SQ(吕守芹);  Liang SL;  Dong C;  Long M(龙勉);  Long, MA (reprint author), Chinese Acad Sci, Inst Mech, Key Lab Micrograv, Beijing 100190, Peoples R China
Adobe PDF(1888Kb)  |  收藏  |  浏览/下载:1295/229  |  提交时间:2012/04/01
Mammary Adenocarcinoma Cells  Hydrodynamic Shear  Melanoma Adhesion  2-dimensional Kinetics  Human Neutrophils  P-selectin  Metastasis Development  Ligand Interactions  Concurrent Binding  Cancer Metastasis  
Probe stiffness regulates receptor-ligand bond lifetime under force 期刊论文
Science China-Physics Mechanics & Astronomy, 2011, 卷号: 54, 期号: 5, 页码: 923-929
作者:  Zhang Y(章燕);  Lv SQ(吕守芹);  Long M(龙勉);  Long, MA (reprint author), Chinese Acad Sci, Inst Mech, Key Lab Micrograv, Beijing 100190, Peoples R China
Adobe PDF(534Kb)  |  收藏  |  浏览/下载:1315/248  |  提交时间:2012/04/01
Probe Stiffness  Bond Lifetime  Optical Trap  Selectin Glycoprotein Ligand-1  P-selectin  Cell-adhesion  Binding-kinetics  Leukocytes  Molecule  Psgl-1  Flow  
Developing A Microfluidic-Based System To Quantify Cell Capture Efficiency 期刊论文
Science in China Series C-Life Sciences, 2009, 卷号: 52, 期号: 2, 页码: 173-181
作者:  Yang F(杨帆);  Gao YX(高宇欣);  Zhang Y(章燕);  Chen J(陈娟);  Long M(龙勉);  Long M
Adobe PDF(794Kb)  |  收藏  |  浏览/下载:798/173  |  提交时间:2009/08/03
Cell Surface Marker  Microfluidic  Capture Efficiency  Ligand Binding-kinetics  Antibody Microarray  Surface-antigens  Leukemias  Identification  Diagnostics  Membrane  Platform  Design  Marker  
Low Spring Constant Regulates P-Selectin-Psgl-1 Bond Rupture 期刊论文
Biophysical Journal, 2008, 页码: 5439-5448
作者:  Zhang Y(章燕);  Sun GY(孙淦云);  Lv SQ(吕守芹);  Li N(李宁);  Long M(龙勉);  Long, MA (reprint author), Chinese Acad Sci, Natl Micrograv Lab, Beijing 100190, Peoples R China.
Adobe PDF(634Kb)  |  收藏  |  浏览/下载:911/202  |  提交时间:2009/08/03
Selectin Glycoprotein Ligand-1  P-selectin  Cell-adhesion  Binding-kinetics  Force  Dissociation  Lifetime  Flow  Microscope  Leukocytes