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FAK-p38 signaling serves as a potential target for reverting matrix stiffness-modulated liver sinusoidal endothelial cell defenestration 期刊论文
BIOMATERIALS, 2024, 卷号: 305, 页码: 17
作者:  Zhang XY(张晓宇);  Li PW(李培文);  Zhou J(周瑾);  Zhang ZL(张子良);  Wu H(吴欢);  Shu XY(舒芯钰);  Li W(李旺);  Wu Y(武亿);  Du Y(杜宇);  Lv DY(吕东媛);  Lv SQ(吕守芹);  Li N(李宁);  Long M(龙勉)
收藏  |  浏览/下载：4/0  |  提交时间：2024/04/02
Liver sinusoidal endothelial cells  Fenestrae  Liver fibrosis  Cytoskeleton remodeling  FAK  MAPK  
Direct mechanical exposure initiates hepatocyte proliferation 期刊论文
JHEP REPORTS, 2023, 卷号: 5, 期号: 12, 页码: 13
作者:  Li, Wang;  Wu Y(武亿);  Hu, Wenhui;  Zhou J(周瑾);  Shu XY(舒芯钰);  Zhang XY(张晓宇);  Zhang, Ziliang;  Wu, Huan;  Du, Yu;  Lv DY(吕东媛);  Lv SQ(吕守芹);  Li N(李宁);  Long M(龙勉)
Adobe PDF(3334Kb)  |  收藏  |  浏览/下载：50/0  |  提交时间：2024/01/02
Mechanotransduction  FAK  hepatic sinusoid chip  
Biomechanics in liver regeneration after partial hepatectomy 期刊论文
FRONTIERS IN BIOENGINEERING AND BIOTECHNOLOGY, 2023, 卷号: 11, 页码: 1165651
作者:  Wu Y(武亿);  Li N(李宁);  Shu XY(舒芯钰);  Li W(李旺);  Zhang XY(张晓宇);  Lv DY(吕东媛);  Long M(龙勉)
Adobe PDF(2065Kb)  |  收藏  |  浏览/下载：60/0  |  提交时间：2023/07/17
liver regeneration  partial hepatectomy  hemodynamics  mechanical loading  mechanotransduction  
Potential Roles of YAP/TAZ Mechanotransduction in Spaceflight-Induced Liver Dysfunction 期刊论文
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES, 2023, 卷号: 24, 期号: 3, 页码: 20
作者:  Li W(李旺);  Shu XY(舒芯钰);  Zhang XY(张晓宇);  Zhang ZL(张子良);  Sun SJ(孙树津);  Li N(李宁);  Long M(龙勉)
Adobe PDF(1498Kb)  |  收藏  |  浏览/下载：115/0  |  提交时间：2023/03/20
microgravity  liver metabolism  mechanosensing  cytoskeleton  nuclear deformation  phase separation  
Trail Formation Alleviates Excessive Adhesion and Maintains Efficient Neutrophil Migration 期刊论文
ACS APPLIED MATERIALS & INTERFACES, 2023
作者:  Hu WH(胡文慧);  Gao WB(高文博);  Gong YX(龚一心);  Guo P(郭盼);  Li W(李旺);  Shu XY(舒芯钰);  Lv SQ(吕守芹);  Zeng, Zhu;  Zhang Y(章燕);  Long M(龙勉)
Adobe PDF(7494Kb)  |  收藏  |  浏览/下载：66/0  |  提交时间：2023/04/20
neutrophil migration  trail release  rear contraction  fi2 integrin  cell adhesion  
Gravity-Vector Induces Mechanical Remodeling of rMSCs via Combined Substrate Stiffness and Orientation 期刊论文
FRONTIERS IN BIOENGINEERING AND BIOTECHNOLOGY, 2022, 卷号: 9, 页码: 14
作者:  Zhang C(张晨);  Lv DY(吕东媛);  Zhang F(张帆);  Wu Y(武亿);  Zheng L(郑鲁);  Zhang XY(张晓宇);  Li Z(李展);  Sun SJ(孙树津);  龙勉Mian
Adobe PDF(3580Kb)  |  收藏  |  浏览/下载：144/44  |  提交时间：2022/05/17
substrate stiffness  orientation  mechanosensing  nucleus translocation  cytoskeletal remodeling  focal adhesion complex reorganization  cellular morphology  
Regulation of hepatic differentiation of human embryonic stem cells by calcium silicate extracts for liver injury repairing 期刊论文
Applied Materials Today, 2020, 卷号: 20, 页码: 100730
作者:  Zheng L;  Lv DY(吕东媛);  Zhang F;  Xing M;  Wang XY;  Jia XH;  Shu XY;  Li PW(李培文);  Lv SQ(吕守芹);  Chang J;  Long M(龙勉)
Adobe PDF(3951Kb)  |  收藏  |  浏览/下载：183/69  |  提交时间：2021/01/29
Human embryonic stem cells  Hepatic differentiation  Hepatocyte-like cells  Calcium silicate extracts  Liver injury repair  
Mechanical strength determines Ca2+ transients triggered by the engagement of beta(2) integrins to their ligands 期刊论文
EXPERIMENTAL CELL RESEARCH, 2020, 卷号: 387, 期号: 2, 页码: 7
作者:  Shu XY(舒芯钰);  Li N(李宁);  Huang DD(黄丹丹);  Zhang Y(章燕);  Lv SQ(吕守芹);  Long M(龙勉)
浏览  |  Adobe PDF(1108Kb)  |  收藏  |  浏览/下载：428/160  |  提交时间：2020/04/07
beta(2) integrin  Ligands  Calcium transients  Bond strength  Mechanotransduction  Shear stress  
Salt bridge interactions within the beta(2) integrin alpha(7) helix mediate force-induced binding and shear resistance ability 期刊论文
FEBS JOURNAL, 2018, 卷号: 285, 期号: 2, 页码: 261-274
作者:  Zhang X(张潇);  Li LD;  Li N(李宁);  Shu XY;  Zhou LW(周吕文);  Lv SQ(吕守芹);  Chen SB;  Mao DB;  Long M(龙勉)
浏览  |  Adobe PDF(2053Kb)  |  收藏  |  浏览/下载：237/61  |  提交时间：2018/10/30
beta(2) integrin  allostery  conformational stability  force  salt bridge interaction  
Microfluidic Synthesis of Hybrid Nanoparticles with Controlled Lipid Layers: Understanding Flexibility-Regulated Cell-Nanoparticle Interaction 期刊论文
ACS NANO, 2015, 卷号: 9, 期号: 10, 页码: 9912-9921
作者:  Zhang L;  Feng Q;  Wang JL(王九令);  Zhang S;  Ding BQ;  Wei YJ(魏宇杰);  Dong MD;  Ryu JY;  Yoon TY;  Shi XH(施兴华);  Sun JS;  Jiang XY;  Jiang, XY (reprint author), Natl Ctr Nanosci & Technol, Beijing Engn Res Ctr BioNanotechnol, Beijing 100190, Peoples R China.
浏览  |  Adobe PDF(1699Kb)  |  收藏  |  浏览/下载：615/310  |  提交时间：2016/01/08
Nanostructures  Lipids  Microfluidics  Interfaces  Drug Deliver