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| FAK-p38 signaling serves as a potential target for reverting matrix stiffness-modulated liver sinusoidal endothelial cell defenestration 期刊论文 BIOMATERIALS, 2024, 卷号: 305, 页码: 17 作者: Zhang XY(张晓宇); Li PW(李培文); Zhou J(周瑾); Zhang ZL(张子良); Wu H(吴欢); Shu XY(舒芯钰); Li W(李旺); Wu Y(武亿); Du Y(杜宇); Lv DY(吕东媛); Lv SQ(吕守芹); Li N(李宁); Long M(龙勉) 收藏  |  浏览/下载:6/0  |  提交时间:2024/04/02 Liver sinusoidal endothelial cells Fenestrae Liver fibrosis Cytoskeleton remodeling FAK MAPK |
| Multiscale biomechanics and mechanotransduction from liver fibrosis to cancer 期刊论文 ADVANCED DRUG DELIVERY REVIEWS, 2022, 卷号: 188, 页码: 114448 作者: Li N(李宁); Zhang XY(张晓宇); Zhou J(周瑾); Li W(李旺); Shu XY(舒芯钰); Wu Y(武亿); Long M(龙勉) Adobe PDF(2553Kb)  |  收藏  |  浏览/下载:318/88  |  提交时间:2022/10/23 Liver tissue stiffness Shear stress Hydrostatic pressure Hepatocytes Hepatocellular carcinoma Liver sinusoidal endothelial cells Hepatic stellate cells Mechanotransduction pathways Mechanomedicine Drug design and delivery |
| Mechanotransduction of liver sinusoidal endothelial cells under varied mechanical stimuli 期刊论文 ACTA MECHANICA SINICA, 2021, 页码: 17 作者: Shu XY(舒芯钰); Li N(李宁); Wu Y(武亿); Li W(李旺); Zhang XY(张晓宇); Li PW(李培文); Lv DY(吕东媛); Lv SQ(吕守芹); Long M(龙勉) Adobe PDF(1359Kb)  |  收藏  |  浏览/下载:367/101  |  提交时间:2021/05/06 Liver sinusoidal endothelial cell Shear stress Mechanical stretch Extracellular matrix Stiffness |
| Characterizing liver sinusoidal endothelial cell fenestrae on soft substrates upon AFM imaging and deep learning 期刊论文 BIOCHIMICA ET BIOPHYSICA ACTA-GENERAL SUBJECTS, 2020, 卷号: 1864, 期号: 12, 页码: 9 作者: Li PW(李培文); Zhou J(周瑾); Li W(李旺); Wu H(吴欢); Hu JR(胡锦荣); Ding QH(丁奇寒); Lv SQ(吕守芹); Pan J; Zhang CY; Li N(李宁); Long M(龙勉) Adobe PDF(4976Kb)  |  收藏  |  浏览/下载:644/373  |  提交时间:2020/11/30 Liver sinusoidal endothelial cells Fenestrae Atomic force microscopy Imaging recognition Fully convolutional networks Substrate stiffness |
| Matrix stiffness and shear stresses modulate hepatocyte functions in a fibrotic liver sinusoidal model 期刊论文 AMERICAN JOURNAL OF PHYSIOLOGY-GASTROINTESTINAL AND LIVER PHYSIOLOGY, 2020, 卷号: 320, 期号: 3, 页码: G272-G282 作者: Li W(李旺); Li PW(李培文); Li N(李宁); Du Y(杜宇); Lv SQ(吕守芹); Elad, David; Long M(龙勉) Adobe PDF(2812Kb)  |  收藏  |  浏览/下载:173/84  |  提交时间:2022/10/25 hepatocytes liver fibrosis matrix stiffness shear flow three-dimensional liver sinusoidal model |
| Influences of Morphology Parameters on the Contact Behavior of a Steel Interface 期刊论文 INTERNATIONAL JOURNAL OF APPLIED MECHANICS, 2020, 卷号: 12, 期号: 1, 页码: 28 作者: Fan LF; Zhao L; Liu XM(刘小明) Adobe PDF(3218Kb)  |  收藏  |  浏览/下载:969/663  |  提交时间:2020/05/18 Sinusoidal asperities contact stiffness elastic-plastic statistical model 18CrMo4 steel interface morphology parameters |
| Mechanical Strength and Structural Basis of beta(2) Integrin to Mediate Neutrophil Accumulation on Liver Sinusoidal Endothelial Cells: A Study Using Atomic Force Microscopy and Molecular Dynamics Simulations 期刊论文 CMES-COMPUTER MODELING IN ENGINEERING & SCIENCES, 2018, 卷号: 116, 期号: 2, 页码: 263-279 作者: Li N(李宁); Zhang X(张潇); Li PW; Yang H; Tong CF; Lv SQ(吕守芹); Zhang Y(章燕); Ye ZY; Pan J; Long M(龙勉) 浏览  |  Adobe PDF(865Kb)  |  收藏  |  浏览/下载:386/188  |  提交时间:2018/10/30 Liver sinusoidal endothelial cells neutrophils beta(2) integrin shear flow mechanical strength |
| Mechanoimmunology of b_2-intergrin-induced adhesion of hepatic cells 会议论文 第九届全国免疫学学术大会, 中国山东济南, 2014-10-18 作者: Tong CF(佟春芳); Yang H(杨浩); Du Y(杜宇); Li N(李宁); Lv SQ(吕守芹); Zhang Y(章燕); Long M(龙勉) 浏览  |  Adobe PDF(809Kb)  |  收藏  |  浏览/下载:193/45  |  提交时间:2015/09/09 Kupffer Interact Sinusoidal Flowing Kinetics Body Predominantly Viewpoint Migrate Integrin |
| The characteristics and estimation of flow through a single rough-walled fracture 期刊论文 JOURNAL OF HYDRODYNAMICS, 2012, 卷号: 24, 期号: 3, 页码: 315-322 作者: Liu QQ(刘青泉); Fan HG(樊红光); Liu, QQ; Chinese Acad Sci, Inst Mech, Lab Environm Mech, Beijing 100190, Peoples R China. Adobe PDF(408Kb)  |  收藏  |  浏览/下载:799/242  |  提交时间:2013/01/18 Fracture Seepage Cubic Law Effective Hydraulic Aperture Non-symmetric Sinusoidal Fracture Rock Joints Fluid-flow Equation Model Law |
| An Approach to Estimate the Flow Through an Irregular Fracture 会议论文 Proceeding of the sixth International Conference on Fluid Mechanics (New Trends in Fluid Mechanics Research), AIP Conf. Proc. Vol. 1376., Guangzhou, China, 2011-06-30~2011-07-03 作者: Liu QQ(刘青泉); Fan HG(樊红光) Adobe PDF(219Kb)  |  收藏  |  浏览/下载:1112/263  |  提交时间:2012/01/13 Fracture Seepage Cubic Law Effective Hydraulic Aperture Non-symmetric Sinusoidal Fracture |