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| FAK-p38 signaling serves as a potential target for reverting matrix stiffness-modulated liver sinusoidal endothelial cell defenestration 期刊论文 BIOMATERIALS, 2024, 卷号: 305, 页码: 17 作者: Zhang XY(张晓宇); Li PW(李培文); Zhou J(周瑾); Zhang ZL(张子良); Wu H(吴欢); Shu XY(舒芯钰); Li W(李旺); Wu Y(武亿); Du Y(杜宇); Lv DY(吕东媛); Lv SQ(吕守芹); Li N(李宁); Long M(龙勉) 收藏  |  浏览/下载:7/0  |  提交时间:2024/04/02 Liver sinusoidal endothelial cells Fenestrae Liver fibrosis Cytoskeleton remodeling FAK MAPK |
| Biomechanics in liver regeneration after partial hepatectomy 期刊论文 FRONTIERS IN BIOENGINEERING AND BIOTECHNOLOGY, 2023, 卷号: 11, 页码: 1165651 作者: Wu Y(武亿); Li N(李宁); Shu XY(舒芯钰); Li W(李旺); Zhang XY(张晓宇); Lv DY(吕东媛); Long M(龙勉) Adobe PDF(2065Kb)  |  收藏  |  浏览/下载:61/0  |  提交时间:2023/07/17 liver regeneration partial hepatectomy hemodynamics mechanical loading mechanotransduction |
| Potential Roles of YAP/TAZ Mechanotransduction in Spaceflight-Induced Liver Dysfunction 期刊论文 INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES, 2023, 卷号: 24, 期号: 3, 页码: 20 作者: Li W(李旺); Shu XY(舒芯钰); Zhang XY(张晓宇); Zhang ZL(张子良); Sun SJ(孙树津); Li N(李宁); Long M(龙勉) Adobe PDF(1498Kb)  |  收藏  |  浏览/下载:117/0  |  提交时间:2023/03/20 microgravity liver metabolism mechanosensing cytoskeleton nuclear deformation phase separation |
| Multiscale biomechanics and mechanotransduction from liver fibrosis to cancer 期刊论文 ADVANCED DRUG DELIVERY REVIEWS, 2022, 卷号: 188, 页码: 114448 作者: Li N(李宁); Zhang XY(张晓宇); Zhou J(周瑾); Li W(李旺); Shu XY(舒芯钰); Wu Y(武亿); Long M(龙勉) Adobe PDF(2553Kb)  |  收藏  |  浏览/下载:319/88  |  提交时间:2022/10/23 Liver tissue stiffness Shear stress Hydrostatic pressure Hepatocytes Hepatocellular carcinoma Liver sinusoidal endothelial cells Hepatic stellate cells Mechanotransduction pathways Mechanomedicine Drug design and delivery |
| Mechanotransduction of liver sinusoidal endothelial cells under varied mechanical stimuli 期刊论文 ACTA MECHANICA SINICA, 2021, 页码: 17 作者: Shu XY(舒芯钰); Li N(李宁); Wu Y(武亿); Li W(李旺); Zhang XY(张晓宇); Li PW(李培文); Lv DY(吕东媛); Lv SQ(吕守芹); Long M(龙勉) Adobe PDF(1359Kb)  |  收藏  |  浏览/下载:367/101  |  提交时间:2021/05/06 Liver sinusoidal endothelial cell Shear stress Mechanical stretch Extracellular matrix Stiffness |
| Characterizing liver sinusoidal endothelial cell fenestrae on soft substrates upon AFM imaging and deep learning 期刊论文 BIOCHIMICA ET BIOPHYSICA ACTA-GENERAL SUBJECTS, 2020, 卷号: 1864, 期号: 12, 页码: 9 作者: Li PW(李培文); Zhou J(周瑾); Li W(李旺); Wu H(吴欢); Hu JR(胡锦荣); Ding QH(丁奇寒); Lv SQ(吕守芹); Pan J; Zhang CY; Li N(李宁); Long M(龙勉) Adobe PDF(4976Kb)  |  收藏  |  浏览/下载:644/373  |  提交时间:2020/11/30 Liver sinusoidal endothelial cells Fenestrae Atomic force microscopy Imaging recognition Fully convolutional networks Substrate stiffness |
| Regulation of hepatic differentiation of human embryonic stem cells by calcium silicate extracts for liver injury repairing 期刊论文 Applied Materials Today, 2020, 卷号: 20, 页码: 100730 作者: Zheng L; Lv DY(吕东媛); Zhang F; Xing M; Wang XY; Jia XH; Shu XY; Li PW(李培文); Lv SQ(吕守芹); Chang J; Long M(龙勉) Adobe PDF(3951Kb)  |  收藏  |  浏览/下载:185/69  |  提交时间:2021/01/29 Human embryonic stem cells Hepatic differentiation Hepatocyte-like cells Calcium silicate extracts Liver injury repair |
| Matrix stiffness and shear stresses modulate hepatocyte functions in a fibrotic liver sinusoidal model 期刊论文 AMERICAN JOURNAL OF PHYSIOLOGY-GASTROINTESTINAL AND LIVER PHYSIOLOGY, 2020, 卷号: 320, 期号: 3, 页码: G272-G282 作者: Li W(李旺); Li PW(李培文); Li N(李宁); Du Y(杜宇); Lv SQ(吕守芹); Elad, David; Long M(龙勉) Adobe PDF(2812Kb)  |  收藏  |  浏览/下载:173/84  |  提交时间:2022/10/25 hepatocytes liver fibrosis matrix stiffness shear flow three-dimensional liver sinusoidal model |
| Binding of intercellular adhesion molecule 1 to beta(2)-integrin regulates distinct cell adhesion processes on hepatic and cerebral endothelium 期刊论文 AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY, 2018, 卷号: 315, 期号: 3, 页码: C409-C421 作者: Tong CF(佟春芳); Zhang Y(章燕); Lv SQ(吕守芹); Li N(李宁); Gong YX(龚一心); Yang H; Feng SL; Du Y; Huang DD; Long M(龙勉) 浏览  |  Adobe PDF(1593Kb)  |  收藏  |  浏览/下载:546/267  |  提交时间:2018/10/30 brain ICAM-1 integrin kinetics liver |
| Mechanical Strength and Structural Basis of beta(2) Integrin to Mediate Neutrophil Accumulation on Liver Sinusoidal Endothelial Cells: A Study Using Atomic Force Microscopy and Molecular Dynamics Simulations 期刊论文 CMES-COMPUTER MODELING IN ENGINEERING & SCIENCES, 2018, 卷号: 116, 期号: 2, 页码: 263-279 作者: Li N(李宁); Zhang X(张潇); Li PW; Yang H; Tong CF; Lv SQ(吕守芹); Zhang Y(章燕); Ye ZY; Pan J; Long M(龙勉) 浏览  |  Adobe PDF(865Kb)  |  收藏  |  浏览/下载:386/188  |  提交时间:2018/10/30 Liver sinusoidal endothelial cells neutrophils beta(2) integrin shear flow mechanical strength |