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Mechanical Strength and Structural Basis of beta(2) Integrin to Mediate Neutrophil Accumulation on Liver Sinusoidal Endothelial Cells: A Study Using Atomic Force Microscopy and Molecular Dynamics Simulations 期刊论文
CMES-COMPUTER MODELING IN ENGINEERING & SCIENCES, 2018, 卷号: 116, 期号: 2, 页码: 263-279
作者:  Li N(李宁);  Zhang X(张潇);  Li PW;  Yang H;  Tong CF;  Lv SQ(吕守芹);  Zhang Y(章燕);  Ye ZY;  Pan J;  Long M(龙勉)
浏览  |  Adobe PDF(865Kb)  |  收藏  |  浏览/下载：381/186  |  提交时间：2018/10/30
Liver sinusoidal endothelial cells  neutrophils  beta(2) integrin  shear flow  mechanical strength  
Neutrophil adhesion and crawling dynamics on liver sinusoidal endothelial cells under shear flow 期刊论文
EXPERIMENTAL CELL RESEARCH, 2017, 卷号: 351, 期号: 1, 页码: 91-99
作者:  Yang H(杨浩);  Li N(李宁);  Du Y(杜宇);  Tong CF(佟春芳);  Lv SQ(吕守芹);  Hu JR;  Zhang Y(章燕);  Long M(龙勉);  Long, M (reprint author), Chinese Acad Sci, Inst Mech, Beijing 100190, Peoples R China.
浏览  |  Adobe PDF(2025Kb)  |  收藏  |  浏览/下载：664/269  |  提交时间：2017/07/24
Neutrophils  Liver Sinusoids  Shear Flow  Adhesive Molecules  Kupffer Cells  
Conformational Stability Analyses of Alpha Subunit I Domain of LFA-1 and Mac-1 期刊论文
PLOS One, 2011, 卷号: 6, 期号: 8, 页码: e24188
作者:  Mao DB(毛德斌);  Lv SQ(吕守芹);  Li N(李宁);  Zhang Y(章燕);  Long M(龙勉);  Mao, DB (reprint author), Chinese Acad Sci, Inst Mech, Key Lab Micrograv, Beijing 100080, Peoples R China
Adobe PDF(818Kb)  |  收藏  |  浏览/下载：1267/285  |  提交时间：2012/04/01
A-domain  Molecular-dynamics  Structural Basis  Integrin Activation  Crystal-structure  Cell-adhesion  T-cell  Neutrophils  Affinity  Migration  
Determining beta(2)-Integrin and Intercellular Adhesion Molecule 1 Binding Kinetics in Tumor Cell Adhesion to Leukocytes and Endothelial Cells by a Gas-driven Micropipette Assay 期刊论文
Journal of Biological Chemistry, 2011, 卷号: 286, 期号: 40, 页码: 34777-34787
作者:  Fu ZL(傅长亮);  Tong CF(佟春芳);  Wang ML;  Gao YX(高宇欣);  Zhang Y(章燕);  Lv SQ(吕守芹);  Liang SL;  Dong C;  Long M(龙勉);  Long, MA (reprint author), Chinese Acad Sci, Inst Mech, Key Lab Micrograv, Beijing 100190, Peoples R China
Adobe PDF(1888Kb)  |  收藏  |  浏览/下载：1295/229  |  提交时间：2012/04/01
Mammary Adenocarcinoma Cells  Hydrodynamic Shear  Melanoma Adhesion  2-dimensional Kinetics  Human Neutrophils  P-selectin  Metastasis Development  Ligand Interactions  Concurrent Binding  Cancer Metastasis  
Surface-Bound Selectin-Ligand Binding Is Regulated By Carrier Diffusion 期刊论文
European Biophysics Journal With Biophysics Letters, 2009, 页码: 701-711
作者:  Sun GY(孙淦云);  Zhang Y(章燕);  Huo B(霍波);  Long M(龙勉);  Long M
Adobe PDF(559Kb)  |  收藏  |  浏览/下载：757/177  |  提交时间：2009/08/03
Association Kinetics  Regulating Factors  Carrier Diffusion  Optical Trap  Selectin  Ligand  Mediated Cell-adhesion  P-selectin  Glycoprotein Ligand-1  Optical Tweezers  Shear-flow  Human Neutrophils  Force Microscopy  Association Rate  Contact Area  Kinetics  
Two-Dimensional Kinetics Of Beta(2)-Integrin And Icam-1 Bindings Between Neutrophils And Melanoma Cells In A Shear Flow 期刊论文
American Journal of Physiology-Cell Physiology, 2008, 页码: C743-C753
作者:  Liang SL;  Fu ZL(傅长亮);  Wagner D;  Guo HG;  Zhan DY;  Dong C;  Long M(龙勉);  Dong, C (reprint author), Penn State Univ, Dept Bioengn, University Pk, PA 16802 USA.
Adobe PDF(727Kb)  |  收藏  |  浏览/下载：712/134  |  提交时间：2009/08/03
Heterotypic Cell Aggregation  Adhesion Molecule  Leukocyte  Tumor Cell  Reverse Rate  Binding Affinity  Probabilistic Model  Polymorpho-nuclear Neutrophils  Intercellular Adhesion Molecule-1  Intercellular-adhesion Molecule-1  Ligand-mediated Adhesion  Hydrodynamic Shear  L-selectin  Malignant-melanoma  Dynamic Regulation  Variant Isoforms  Stable Adhesion  Latex Spheres  P-selectin  
Impact of carrier stiffness and microtopology on two-dimensional kinetics of P-selectin and P-selectin glycoprotein ligand-1 (PSGL-1) interactions 期刊论文
Journal of Biological Chemistry, 2007, 卷号: 282, 期号: 13, 页码: 9846-9854
作者:  Wu L;  Xiao BT;  Jia XL(贾潇凌);  Zhang Y(章燕);  Lv SQ(吕守芹);  Chen J(陈娟);  Long M(龙勉);  Long, M (reprint author), Chinese Acad Sci, Inst Mech, Natl Micrograv Lab, Beijing 100080, Peoples R China.
Adobe PDF(457Kb)  |  收藏  |  浏览/下载：1063/175  |  提交时间：2009/08/03
Human Neutrophils  Binding-kinetics  Adhesion  Affinity  Rates  Flow