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Title:
Particle manipulations in non-Newtonian microfluidics: A review
Author: Lu, Xinyu; Liu, Chao; Hu GQ(胡国庆); Xuan, Xiangchun
Source: JOURNAL OF COLLOID AND INTERFACE SCIENCE
Issued Date: 2017-08-15
Volume: 500, Pages:182-201
Abstract: Microfluidic devices have been widely used since 1990s for diverse manipulations of particles (a general term of beads, cells, vesicles, drops, etc.) in a variety of applications. Compared to the active manipulation via an externally imposed force field, the passive manipulation of particles exploits the flow-induced intrinsic lift and/or drag to control particle motion with several advantages. Along this direction, inertial microfluidics has received tremendous interest in the past decade due to its capability to handle a large volume of samples at a high throughput. This inertial lift-based approach in Newtonian fluids, however, becomes ineffective and even fails for small particles and/or at low flow rates. Recent studies have demonstrated the potential of elastic lift in non-Newtonian fluids for manipulating particles with a much smaller size and over a much wider range of flow rates. The aim of this article is to provide an overview of the various passive manipulations, including focusing, separation, washing and stretching, of particles that have thus far been demonstrated in non-Newtonian microfluidics. (C) 2017 Elsevier Inc. All rights reserved.
Keyword: Elastic lift ; Inertial lift ; Particle focusing ; Particle separation ; Particle washing ; Particle stretching
Language: 英语
Indexed Type: SCI ; EI
Corresponding Author: Xuan, XC (reprint author), Clemson Univ, Dept Mech Engn, Clemson, SC 29634 USA.
Correspondent Email: xcxuan@clemson.edu
DOI: 10.1016/j.jcis.2017.04.019
DOC Type: Review
WOS Subject: Chemistry, Physical
WOS Subject Extended: Chemistry
WOS Keyword Plus: PINCHED FLOW FRACTIONATION ; NEUTRALLY BUOYANT PARTICLES ; DILUTE POLYMER-SOLUTIONS ; VISCOELASTIC FLUIDS ; LATERAL MIGRATION ; POISEUILLE FLOW ; CELL-SEPARATION ; SHEAR-FLOW ; RECTANGULAR MICROCHANNELS ; NUMERICAL SIMULATIONS
WOS ID: WOS:000401303000022
ISSN: 0021-9797
Rank: [Lu, Xinyu; Xuan, Xiangchun] Clemson Univ, Dept Mech Engn, Clemson, SC 29634 USA; [Liu, Chao; Hu, Guoqing] Chinese Acad Sci, Inst Mech, Beijing Key Lab Engineered Construct & Mechanobio, State Key Lab Nonlinear Mech, Beijing 100190, Peoples R China
Classification: 二类/Q1
Ranking: 3
Citation statistics:
Content Type: 期刊论文
URI: http://dspace.imech.ac.cn/handle/311007/72130
Appears in Collections:非线性力学国家重点实验室_期刊论文

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Recommended Citation:
Lu, Xinyu,Liu, Chao,Hu GQ,et al. Particle manipulations in non-Newtonian microfluidics: A review[J]. JOURNAL OF COLLOID AND INTERFACE SCIENCE,2017-08-15,500:182-201.
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